@eLife

The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity

 Cambridge, UK
elifesciences.org
Joined September 2011
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A real-time, multi-animal model for automatic face detection and identification of freely moving common marmosets based on YOLOv8 algorithms elifesciences.org/articles/1…

A real-time, multi-animal model for automatic face detection and identification of freely moving...

A generalizable computational approach automatically identifies individual common marmosets to serve as support for presenting and analyzing behavioral tasks without relying on extensive manual work.

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Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons elifesciences.org/articles/1…

Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle...

Single-molecule motility assays and live-cell imaging in neurons reveal that tau hyperphosphorylation disrupts the formation of cooperative tau envelopes along microtubules and lysosomal transport.

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Selective lifelong suppression of an odor processing channel in response to critical period experience elifesciences.org/articles/1…

Selective lifelong suppression of an odor processing channel in response to critical period...

Utilizing the olfactory system of Drosophila, a critical period paradigm has provided new insight into the selectivity and longevity of the impact of early life experiences on sensory system circui...

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Bifunctional architecture enables substrate catalysis and channeling in Paracoccus TMAO demethylase elifesciences.org/articles/1…

Bifunctional architecture enables substrate catalysis and channeling in Paracoccus TMAO demethylase

Trimethylamine N-oxide demethylase uses substrate channeling to couple trimethylamine N-oxide demethylation with one-carbon metabolism, safely detoxifying formaldehyde while enhancing metabolic...

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Opening the black box toward a modular approach to spike sorting elifesciences.org/articles/1…

Opening the black box toward a modular approach to spike sorting

Modularized spike sorting pipelines can identify performance bottlenecks, lower contribution barriers, and enable the development of highly accurate algorithms to turn extracellular recordings into...

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Two Glu/Asp residues cooperatively mediate an early step of ATP hydrolysis in GHKL ATPases MutL and GyrB elifesciences.org/articles/1…

Two Glu/Asp residues cooperatively mediate an early step of ATP hydrolysis in GHKL ATPases MutL and...

A cooperative catalytic mechanism provides a revised framework for understanding ATP hydrolysis in a broad subset of GHKL ATPases.

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Retinal curl as a functional signal for heading estimation beyond the focus of expansion elifesciences.org/articles/1…

Retinal curl as a functional signal for heading estimation beyond the focus of expansion

The rotational retinal flow generated by natural gaze stabilization is not merely visual noise to be subtracted but actively shapes human heading perception.

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Integrated respirometry and metabolomics unveil circadian metabolic dynamics in Drosophila elifesciences.org/articles/1…

Integrated respirometry and metabolomics unveil circadian metabolic dynamics in Drosophila

Wild-type flies anticipate daily respiratory demands by coordinating substrate use, whereas short-sleep and clock-deficient mutants shift toward reactive fuel use and altered redox metabolism.

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Developmental synchrony of retinal waves, apoptosis, and angiogenesis in postnatal retina elifesciences.org/articles/1…

Developmental synchrony of retinal waves, apoptosis, and angiogenesis in postnatal retina

An interdisciplinary approach uncovers a never-before-seen multifaceted synchrony of developmental processes in the rodent retina which are driven by purinergic signalling from apoptotic retinal...

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What's it like publishing in the eLife Model? In this collection, authors share their thoughts on the eLife Model, tell us about their research and offer advice to researchers who are thinking about publishing with eLife. elifesciences.org/highlights…

Publishing in the eLife Model: An author’s perspective

Hear from some of our authors about their experience of publishing with us.

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Cellular basis of accelerated whole-tooth regeneration elifesciences.org/articles/1…

Cellular basis of accelerated whole-tooth regeneration

Tooth plucking triggers a rapid, coordinated regeneration program in cichlids, accelerating replacement more than threefold through temporally organized epithelial, mesenchymal, immune, vascular, and...

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Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control elifesciences.org/articles/1…

Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control

The open-source closed-loop system enables mice to learn modulation of cortical activity or movement by providing a platform for testing brain-behavior relationships in motor learning and neuroreha...

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Staph’s fast track into cells elifesciences.org/digests/10…

Staph’s fast track into cells

The route Staphylococcus aureus takes into host cells determines how quickly it reaches the cell interior, multiplies and kills the cells, revealing a potential new target for tackling chronic...

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We're looking for an experienced publishing professional with a strong technical background in digital workflows, XML infrastructure, and open science practices to join us as Head of Content Operations. Find out more and apply by November 20, 2026: elifesciences.org/jobs/e684f…
eLife Jobs listing: Head of Content Operations — apply by November 20, 2026; bold white text on a dark green background with diagonal light- and dark-green capsule and dot graphic accents.

ALT eLife Jobs listing: Head of Content Operations — apply by November 20, 2026; bold white text on a dark green background with diagonal light- and dark-green capsule and dot graphic accents.

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Region-specific mechanosensation modulates Drosophila postural control behaviour elifesciences.org/articles/1…

Region-specific mechanosensation modulates Drosophila postural control behaviour

Behavioural, optogenetic, and gene expression analyses demonstrate that regional mechanosensory processes instructed by Hox gene inputs are essential for postural control in Drosophila larvae linking...

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Episode 105: September 2026 elifesciences.org/podcast/ep…

Episode 105: September 2026

In this episode, we hear about the origins of our individuality, how synaesthetes' pupil size changes just by thinking of a colour, female chickadees expanding the spectrum of cognitive abilities...

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Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep elifesciences.org/articles/1…

Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs...

A state-dependent inhibitory dopaminergic microcircuit co-regulates sleep and long-term memory via distinct signaling cascades.

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We're delighted to hear that our Deputy Editor Diane Harper and Reviewing Editor Shimon Sakaguchi have been elected to the National Academy of Medicine: buff.ly/sqsCHY2

NAM Elects 100 New Members for 2026 - NAM

Meet the National Academy of Medicine’s Class of 2026. Explore the new members recognized for their contributions to health, medicine, and science.

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4/ Shimon for his groundbreaking discovery of regulatory T cells that confer dominant suppression of potentially inflammatory immune responses, elucidation of these cell properties, including their dependence on Foxp3 expression, and development of novel therapeutic strategies.
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5/ Many congratulations to both of them on this latest acheivement!
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