Research group @IMBA_Vienna and the @viennabiocenter.
Vienna, Austria
Joined March 2019
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The Knoblich Lab retweeted
[1/6] Excited to share our work on bioRxiv! bit.ly/47CryUl at @Knoblich_lab. This project has been a huge part of my life, through some hard years, so seeing it come together feels special. I’ve long been fascinated by networks—especially the brain.
🎉 As the year winds down, we are filled with gratitude for an inspiring year of science, collaboration, and discovery. Wishing you all a joyful festive season and a bright, groundbreaking 2025 ahead! 🧬🔬🌟
The Knoblich Lab retweeted
Increased stress through #DNAbreaks with simultaneous inhibition of #DNArepair in the #tumourcell. ️A team from #MedUniVienna and #UniversityHospitalVienna identified a new therapeutic approach for diffuse hemispheric #glioma. ➡ bit.ly/49iFC5q
@gojojohannes @NeuroOnc
The Knoblich Lab retweeted
A new preprint from the @Knoblich_lab and colleagues from @MaxPerutzLabs and @CeMM_News characterizes how different protocols and starting cell lines affect the variety of cell types in brain organoids. The team also proposes improved protocols for producing brain organoids.
Excited to share our latest preprint (@biorxivpreprint) on brain organoid development. Lead by Julia Naas and Meritxell Balmaña (@txellbalmana) with Arndt von Haeseler, Christopher Esk (@christopher_esk) and colleagues across Vienna. @MaxPerutzLabs, @IMBA_Vienna, @CeMM_News.
Excited to share our latest preprint (@biorxivpreprint) on brain organoid development. Lead by Julia Naas and Meritxell Balmaña (@txellbalmana) with Arndt von Haeseler, Christopher Esk (@christopher_esk) and colleagues across Vienna. @MaxPerutzLabs, @IMBA_Vienna, @CeMM_News.
We also provide RNA-seq data for cell lines in all protocols across organoid development. We quantify sources of variability (1. organoid developmental stage, 2. protocol, 3. cell line) and provide early signatures consistent with protocol-driven organoid derivation.
All data is easily accessible in our Vienna brain organoid data explorer. You can look for your favorite gene or search for entire biological processes based on GO Terms. Check it out: vienna-brain-organoid-explor…
The Knoblich Lab retweeted
Save the date for the Athens International Symposium on 3-4 April 2025! Join scientists as they share their latest research on neural stem cells. Registration & abstract submission will open in October 👉 bit.ly/4diDKtK
@VanderhaeghenP2 @studerl @BrunetLab @Knoblich_lab
The Knoblich Lab retweeted
New paper alert! The @Knoblich_Lab partnered with researchers at the @humantechnopole and @unimib to develop new brain organoids with distinct cortical areas and front-to-back patterning and study human-specific brain development and disorders. Read more: bit.ly/3ZK5wMX
The Knoblich Lab retweeted
Excited to share this work now published @naturemethods and to have contributed to develop this interesting model of cortical patterning. A fantastic collaborative work with another @Knoblich_Lab alumnus @BosoneCamilla , @castaldi_davide @CarloEmanueleV1 @humantechnopole
New paper alert! The @Knoblich_Lab partnered with researchers at the @humantechnopole and @unimib to develop new brain organoids with distinct cortical areas and front-to-back patterning and study human-specific brain development and disorders. Read more: bit.ly/3ZK5wMX
The Knoblich Lab retweeted
I am beyond happy to share that our polarized cortical assembloid (polCA) paper is out today in Nature Methods! nature.com/articles/s41592-0…
The Knoblich Lab retweeted
The @Knoblich_lab has developed polarized cortical assembloids with the help of a localized FGF8 source. This technology allows mimicking patterning events during brain development.
@krenn_veronica @BosoneCamilla @castaldi_davide @gtesta72
nature.com/articles/s41592-0…
The Knoblich Lab retweeted
Chong Li, postdoc at the #Knoblich_Lab, will soon leave IMBA to take a new position as group leader at the Chinese Institute for Brain Research (@chinese_brain). Learn more about Chong’s journey at IMBA and his future position here: bit.ly/ChongLiExit
The Knoblich Lab retweeted
Extremely grateful for the support of the @Knoblich_lab and @IMBA_Vienna during this postdoc journey, where I met amazing scientists from around the world! Excited to start my own group soon at CIBR to continue exploring some of the most fascinating areas of human brain research!
Chong Li, postdoc at the #Knoblich_Lab, will soon leave IMBA to take a new position as group leader at the Chinese Institute for Brain Research (@chinese_brain). Learn more about Chong’s journey at IMBA and his future position here: bit.ly/ChongLiExit
The Knoblich Lab retweeted
I m happy to present our latest preprint, and the main work of my PhD-project:
"GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator"
In this manuscript we introduce a new normalization method for scRNA-seq data.
GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator biorxiv.org/cgi/content/shor… #biorxiv_bioinfo