Cutting-edge research, news, commentary, and visuals from the Science family of journals. Follow @NewsfromScience for stories from our News team.
Washington, DC & Cambridge, UK
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Researchers have developed an AI-based approach to help physicians with real-life clinical workups, starting with the patient’s chief complaint, systematically asking questions and deciding what laboratory and imaging tests to order, and then continuing the evaluation on the basis of the answers received.
Learn more this week in Science: scim.ag/3U8xn94
ALT This image depicts a patient and a physician working together with artificial intelligence (AI) to reach a diagnosis.
By applying a unique polyene scaffold, researchers engineer a next-generation, broad-spectrum antifungal that selectively targets ergosterol without binding to cholesterol, avoiding severe toxicity linked to drugs like amphotericin B.
Find out more in @ScienceTM: scim.ag/3UycT9T
Animals and plants use conceptually similar immune systems to detect microbes and activate defenses. In both lineages, pattern recognition receptors (PRRs) perceive pathogen- or microbe-associated molecular patterns (PAMPs or MAMPs) and host-derived damage-associated molecular patterns (DAMPs).
Whereas animals rely on specialized immune cells, plants harness individual cells expressing diverse PRRs. In the apoplast, which lies outside the plasma membrane and includes the cell wall, PRRs detect immunogenic fragments released from microbial proteins by plant hydrolytic enzymes. Conversely, pathogen-secreted enzymes can degrade constituents of the apoplast, generating DAMPs that activate immunity.
In three new Science papers, researchers report expansions of this surveillance, revealing receptor architectures and mechanisms that enable plants to discriminate immunogenic carbohydrates. The findings illustrate how ligand specificity and receptor assembly confine immune activation to the context of microbial challenge.
Learn more in a new #SciencePerspective: scim.ag/4ib9BRC
Last call: Apply for the BioInnovation Institute & Science Prize for Innovation
This prize recognizes bold researchers who are asking fundamental questions at the intersection of the life sciences and entrepreneurship.
The Grand Prize winner will receive a cash prize of USD 25,000 and have their winning essay published in Science, in print and online.
Apply by 1 November 2026: bit.ly/3TuI19S
ALT The image features a logo with the words "BII Science Prize for Innovation" written in dark lettering.
Researchers in @ScienceAdvances have developed a multiplexed and implantable fiber sensor that monitors the bloodstream for real-time levels of sodium and potassium, two electrolytes that regulate important bodily functions like heart rhythm and fluid balance. scim.ag/4yyM9UE
ALT This image illustrates the process of a blood glucose analysis (BGA) system. It shows an ex vivo BGA setup with labeled steps: blood extraction, sample delivery, analysis, and result reporting. A diagram of in vivo real-time monitoring is displayed, with MIFS technology highlighted and immediate display on a digital device. Another section shows a detailed process sequence involving LM injection, hole punching, and sensor electrode placement. There are microscopic images of electrodes and detailed views of components labeled as Na+, K+, WE, and RE. Components like TPU and various materials are highlighted in different steps.
Japan’s MMX mission aims to retrieve samples from Mars’s mysterious moon. They could reveal how it formed—and hold pieces of Mars itself.
Learn more: scim.ag/4sgWWRI @NewsfromScience
A @ScienceTM analysis of trial data from stem cell transplant recipients shows how immune suppression with either cyclophosphamide or tacrolimus shapes T cell reconstitution—and has opposing effects on the risk of graft-versus-host disease or infection post-transplant. scim.ag/47xj5BT
"For years, I worked hard to hide my history of homelessness. Now, I am more neutral—it was a challenging and sometimes unpleasant chapter, like puberty, or, more recently, learning Bayesian statistics. I am committed to not letting my history define me. But I also don’t want my colleagues to assume no scientist could have a past like mine." #ScienceWorkingLife scim.ag/4jAvtZd
ALT An illustration of a person behind a tree looking at a coyote. The hedline reads: I used to be homeless. That experience shapes my science
New in @SciRobotics: The Ultra Mobility Vehicle bicycle robot leverages its own inertia and momentum to perform jumps, track stands, wheelies and other athletic moves. scim.ag/4yyunAT
Science is publishing an Erratum to replace the July 2026 Editorial Expression of Concern for the February 2026 Research Article “Hafnium oxide interface stabilization for efficient, photothermally stable perovskite solar cells.” scim.ag/4z1WcT5
How does the #glycome of gamma-delta T cells affect their activation toward an autoimmune state?
Learn more in Science #Immunology about these important sugar molecules and their impact on inflammatory disease. scim.ag/47UlTJn
Does generative AI dilute markets for human-created work?
In a new #SciencePolicyForum, researchers discuss how market dilution theory, which could affect AI use in science, requires conceptual clarity and empirical evidence: scim.ag/4eDnln9
ALT A black background displays a quote: "... this theory lacks a conceptually meaningful definition." Attributed to Samuelson et al. in white text.
Wolves have made a spectacular comeback in Europe. But attacks on livestock and humans have caused a heated debate about the limits of coexistence.
Learn more: scim.ag/4oNnWa4
ALT Map of wolf populations in Europe, with 9 distinct populations color-coded and labeled: Scandinavian, Karelian, Baltic, Central European, Carpathian, Dinaric-Balkan, Italian Peninsula, Alpine, and Iberian.
People who lived 5500 years ago on the shores of Siberia’s Lake Baikal survived by hunting deer and game and catching fish. At times, marmots were on the menu, too—a decision with deadly consequences.
Learn more: scim.ag/4sdUV9f
ALT The earliest plague epidemics may have been caused by marmots
In the 1950s, scientists tried to define "normal" humans. The problem? They couldn't find any.
The Normals, a #SciencePodcast🎙️ series that explores this story, has won Silver in the Science & Education: Limited Series and Specials category at the @signalawards!
Check out the award-winning series: scim.ag/4bWMKr9
Researchers in Science report that many birds use vertical winds or gradual changes in wind speed or direction (wind shear) to soar, thereby reducing their cost of transport by switching from costly flapping flight to gliding flight.
📄: scim.ag/4dJr0Qc
#SciencePerspective: scim.ag/4yVNzth
Science Magazine retweeted
🐟 How many times have fish evolved suction cups? Research led by Scripps PhD student Emily McFarland found that suction cups evolved at least 3 times independently in nearly 1,000 fish species! Dive into the study featured in @ScienceMagazine. ⤵️
science.org/content/article/…
Science Magazine retweeted
We didn't know about the role of alternative RNA splicing for response to cancer immunotherapy. Discovery of STAT2 introns that influence non-small cell lung cancer response and survival (PSI=percent spliced in) @ScienceMagazine
science.org/doi/10.1126/scie…
Using genome editing to trace cell lineages, researchers have captured the early history of the mouse embryo in unprecedented detail.
Learn more: scim.ag/4z5PhIP @NewsfromScience
A new device can detect scents and transmit them between people across distances, with the potential for long-range transmission.
It marks another stage in the development of human-machine interfaces: enabling the sharing of smell.
Learn more in @ScienceAdvances: scim.ag/47z6fTL
Researchers in Science have developed an AI-based approach to help physicians with real-life clinical workups. The system shows promise in supplementing a physician’s workflow.
Learn more: scim.ag/4sfzsfP
