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トンヌラ

@37phoenix

へっぽこ内科医。なんちゃって感染症専門医。論文メモ。

 Japan
Joined November 2011
  • Tweets4.9K
  • Following160
  • Followers2.2K
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砂糖入り飲料やフルーツジュースの摂取は高血圧のリスクを上昇させる。Circulation. 2026;154:912. PMID: 42324999. pubmed.ncbi.nlm.nih.gov/4232…
Consumption of Fructose-Containing Food and Beverage Sources in Childhood Through to Adulthood and...

Consumption of Fructose-Containing Food and Beverage Sources in Childhood Through to Adulthood and...

SSB and fruit juice intakes were positively associated with a higher risk of hypertension independently of overall diet quality, physical activity, and other factors. Our findings support public...

pubmed.ncbi.nlm.nih.gov
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高齢者の膵嚢胞病変や肝細胞癌のサーベイランス。Expert review. Clin Gastroenterol Hepatol. PMID; 42820904. pubmed.ncbi.nlm.nih.gov/4282…
AGA Clinical Practice Update on Surveillance of Pancreatic Cystic Lesions and Hepatocellular...

AGA Clinical Practice Update on Surveillance of Pancreatic Cystic Lesions and Hepatocellular...

This expert review was commissioned and approved by the AGA Institute Clinical Practice Updates Committee and the AGA Governing Board to provide timely guidance on a topic of high clinical importance...

pubmed.ncbi.nlm.nih.gov
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腎細胞がんのreview. BMJ. 2026;395:e100785. PMID: 42933810. pubmed.ncbi.nlm.nih.gov/4293…
Advances in the management of renal cell carcinoma - PubMed

Advances in the management of renal cell carcinoma - PubMed

Renal cell carcinoma (RCC) is the most common form of kidney cancer, with 435 000 patients newly diagnosed worldwide each year. In addition to morphology and histology, molecular subtyping has...

pubmed.ncbi.nlm.nih.gov
165
多剤耐性グラム陰性菌血流感染に対して早期の最適な治療は死亡率の減少と関連した。第３世代セファロスポリン耐性菌で効果は観察され、カルバペネム耐性菌での効果は不確実だった。Luca Mezzadri. eClinicalMedicine. sciencedirect.com/science/ar…
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ICUでの肺炎。Review. Nat Commun.2026;17:10875. PMID; 42888246. pubmed.ncbi.nlm.nih.gov/4288…
ICU-acquired pneumonia beyond pathogen detection - PubMed

ICU-acquired pneumonia beyond pathogen detection - PubMed

Intensive care unit-acquired pneumonia is often treated as a binary diagnosis, although clinical deterioration, imaging and microbial detection describe different aspects of disease. This Perspective...

pubmed.ncbi.nlm.nih.gov
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E fafecalis菌血症と心内膜炎。SR&MA. 心内膜炎の有病率は粗有病率で11.8％、系統的な心エコーが行われた研究では24.2％。DENOVAの感度88.7％、特異度84％。NOVAは感度95.6％、特異度30.7％.EClicalMedicine. PMID: 42923940. pubmed.ncbi.nlm.nih.gov/4292…
Enterococcus faecalis bacteraemia and infective endocarditis: a systematic review and meta-analysis...

Enterococcus faecalis bacteraemia and infective endocarditis: a systematic review and meta-analysis...

Cassa di Risparmio di Trento e Rovereto (GRAM+ TN project).

pubmed.ncbi.nlm.nih.gov
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化膿性関節炎のreview. Clin Infect Dis. 2026;83:499. PMID: 42950136. pubmed.ncbi.nlm.nih.gov/4295…
State-of-the-Art Review: Native Joint Septic Arthritis Epidemiology, Pathogenesis, Microbiology,...

State-of-the-Art Review: Native Joint Septic Arthritis Epidemiology, Pathogenesis, Microbiology,...

Native joint septic arthritis (NJSA) is a time-sensitive orthopedic and infectious diseases emergency associated with substantial morbidity, mortality, and long-term functional impairment. This...

pubmed.ncbi.nlm.nih.gov
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心臓植え込みデバイス感染症の治療期間。抜去からの治療中央値は28日、血液培養陰性化から31.5日。90日死亡3.8％。再燃は3.8％。Bennett Collis. CMI Commun. cmi-comms.org/article/S2950-…
Duration of Therapy for Bacteremic Cardiac Implantable Electronic Device Infections

Duration of Therapy for Bacteremic Cardiac Implantable Electronic Device Infections

Infection of a cardiac implantable electronic device (CIED) is a Class I indication for device removal.1-4 While there is substantial evidence demonstrating the clinical benefits of extracting an...

cmi-comms.org
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急性副鼻腔炎のガイドライン要約。JAMA. PMID: 42949730. pubmed.ncbi.nlm.nih.gov/4294…
Diagnosis and Management of Acute Rhinosinusitis in Adults - PubMed

Diagnosis and Management of Acute Rhinosinusitis in Adults - PubMed

Diagnosis and Management of Acute Rhinosinusitis in Adults

pubmed.ncbi.nlm.nih.gov
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血液悪性腫瘍で導入化学療法を行う患者に対して週2回のムーコル症の血漿PCRスクリーニングを行ったところ、6％で陽性となった。ムーコル症に対する血症PCRは感度83.3％、特異度99.6％、陽性的中率52.6％、陰性的中率99.9％だった。 Open Forum Infect Dis.2026;ofag696. academic.oup.com/ofid/articl…
A multicenter interventional trial using blood Mucorales PCR as a screening tool in high-risk...

A multicenter interventional trial using blood Mucorales PCR as a screening tool in high-risk...

AbstractBackground. Mucormycosis (MCM) is a life-threatening invasive mould infection. Patients with prolonged neutropenia or undergoing allogeneic hematop

academic.oup.com
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骨関節感染に対するリネゾリドとテジゾリドの効果と血液安全性の比較。治療失敗や再発、死亡においてテジゾリドはリネゾリドに非劣勢。血液安全性はテジゾリドのほうが好ましい。Infect Dis Ther. PMID: 42944841. pubmed.ncbi.nlm.nih.gov/4294…
Comparative Effectiveness and Hematological Safety of Linezolid and Tedizolid in Bone and Joint...

Comparative Effectiveness and Hematological Safety of Linezolid and Tedizolid in Bone and Joint...

Tedizolid was non-inferior to linezolid for the treatment of BJIs and was associated with improved hematological safety. These findings support the use of tedizolid as a valuable alternative in...

pubmed.ncbi.nlm.nih.gov
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グラム陰性菌の耐性。Review. N Engl J Med. 2026;395:1728. PMID: 42950203. pubmed.ncbi.nlm.nih.gov/4295…
Gram-Negative Bacterial Resistance - PubMed

Gram-Negative Bacterial Resistance - PubMed

The rapid worldwide spread of antimicrobial resistance among gram-negative bacteria is driven by a complex interplay of human, environmental, and health care-associated factors and accelerated by...

pubmed.ncbi.nlm.nih.gov
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GLP1RAと比較するとSGLT2阻害薬は尿中の酵母陽性やグラム陽性菌の陽性率が高かったが、グラム陰性菌は増えなかった。糖尿病患者より非糖尿病患者で培養要請が多かった。UTI関連の入院は稀であった。Oren Biham. Clin Microbiol Infect. clinicalmicrobiologyandinfec…
SGLT2 Inhibitors and risk of bacteriuria, candiduria, and UTI-related hospitalization: A Nationwide...

SGLT2 Inhibitors and risk of bacteriuria, candiduria, and UTI-related hospitalization: A Nationwide...

SGLT2 inhibitors induce glycosuria; however, pathogen-specific real-world data on UTI risk are scarce, particularly in individuals without diabetes. We compared positive urine cultures, UTI-related...

clinicalmicrobiologyandinfection.org
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血流感染患者における経口スイッチ。7日目までに32.3％、退院までに44.6％が経口スイッチされた。シプロ31.3％、スルタミシリン23.3％、セフロキシム11.3％。Lea A Nikolai. Open Forum Infect Dis. 2026:ofag666. academic.oup.com/ofid/articl…
Prevalence, determinants and outcomes of intravenous to oral switch of antibiotic therapy in...

Prevalence, determinants and outcomes of intravenous to oral switch of antibiotic therapy in...

In a tertiary care setting, intravenous to oral antibiotic switch was underused in clinically stable patients with bloodstream infection. Implementation ba

academic.oup.com
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非複雑性UTIに対するニトロフラントインとホスホマイシンの比較。SR&MA. Int Urogynecol J. PMID: 42850453. pubmed.ncbi.nlm.nih.gov/4285…
Comparative Efficacy and Safety of Nitrofurantoin Versus Fosfomycin for Acute Uncomplicated Lower...

Comparative Efficacy and Safety of Nitrofurantoin Versus Fosfomycin for Acute Uncomplicated Lower...

Nitrofurantoin and single-dose fosfomycin are both effective treatment options for uncomplicated cystitis. Treatment choice may be influenced by pregnancy, dosing regimen, and adherence considerati...

pubmed.ncbi.nlm.nih.gov
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心血管ケアとしての成人予防接種。Review. J Am Coll Cardiol. PMID: 42554529. pubmed.ncbi.nlm.nih.gov/4255…
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持続Enterococcus faecium菌血症におけるダプトマイシン耐性の出現。ケースレポート。Int J Infect Dis. 2026:109208. PMID: 42933528. pubmed.ncbi.nlm.nih.gov/4293…
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抗菌薬の選択は物語のごく一部。耐性から持続性へ。Comment. Lancet Microbe.2026. PMID: 42925879.　pubmed.ncbi.nlm.nih.gov/4292…
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重症市中肺炎に対してプロカルシトニンの使用は抗菌薬使用日数の減少と関連した(0.5日短縮)。特に安定例で差が顕著であった。Infect Control Hosp Epidemiol. PMID: 42894885. pubmed.ncbi.nlm.nih.gov/4289…
Real-world use of procalcitonin for antimicrobial stewardship in severe community-acquired pneumo...

Real-world use of procalcitonin for antimicrobial stewardship in severe community-acquired pneumo...

PCT testing was associated with shorter antibiotic duration, especially among stable patients, but was performed without regard to clinical stability. Reserving PCT testing for stable patients may...

pubmed.ncbi.nlm.nih.gov
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骨関節に対する短期治療と長期治療の比較。メタ解析。ITT解析では短期と長期で治療失敗に差はない。短期では抗菌薬関連有害事象が少ない。perprotocol解析では短期治療は治療失敗と関連。Infection. PMID: 42895606. pubmed.ncbi.nlm.nih.gov/4289…
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