@AJOrgChem

Senior scientist II at Domainex. Formerly PhD Student in the Browne Research Group

 Cardiff, Wales
Joined October 2018
  • Tweets84
  • Following165
  • Followers108
8Media
Mechanochemistry 🤝 continuous synthesis Check out this tutorial review I co-wrote on continuous extrusion, including the benefits it can offer organic synthesis!🦾 ⚙️⚙️ pubs.rsc.org/en/content/arti…… @BrowneGroup @RRBolt97 @JamieLeitch165 @WillNicholson18 @DuncanLBrowne

Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis

Rapid and wide-ranging developments have established mechanochemistry as a powerful avenue in sustainable organic synthesis. This is primarily due to uniqu

pubs.rsc.org
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Publication cake to congratulate @AJOrgChem and @ChemMattChem for their work on mechanical activation of zero-valent metal reductants for nickel-catalyzed cross-electrophile coupling @ACSCatalysis with @DuncanLBrowne @School_Pharmacy @ChemistryCU pubs.acs.org/doi/10.1021/acs…
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We are thrilled to share a new HF-free technology that converts fluorspar to fluorochemicals. Enormous congratulations to the amazing team of chemists who made this recurring dream a reality! science.org/doi/10.1126/scie… @CalumPatel @ScienceMagazine @OxfordChemistry @Fluo_Rok
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Featured in our One year of Nature Synthesis collection nature.com/collections/jbiih… A Review by @AJOrgChem @JamieLeitch165 @Science_Hag @DuncanLBrowne @BrowneGroup Mechanochemical techniques for the activation and use of zero-valent metals in synthesis nature.com/articles/s44160-0…
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Mechanochemists Want to Shake up Industrial Chemistry dx.doi.org/10.1021/acscentsc…

Mechanochemists Want to Shake up Industrial Chemistry

Grinding stuff is probably one of the oldest ways to run a chemical reaction.

pubs.acs.org
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Congrats to @alexseastram for passing his PhD viva today @ChemistryCU - 7th from the group! Thanks to Dr Alastair Lennox and @rebecca_melen for examining!
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Our paper on the mechanochemical cross-electrophile coupling of twisted amides OR heteroaryl halides with alkyl halides is out now. Congrats to @AJOrgChem and @ChemMattChem for all their hard work! pubs.acs.org/doi/10.1021/acs…
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WE ARE HIRING Postdoc/research fellow position working on enabling tech in collaboration with @rebecca_melen and Ade Porch @cardiffuni Closing date 29th Aug Please share ⭐⭐⭐⭐ atsv7.wcn.co.uk/search_engin…
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Now online: Review by @AJOrgChem @JamieLeitch165 @Science_Hag @DuncanLBrowne @BrowneGroup at @School_Pharmacy @UCL @ChemistryCU Mechanochemical techniques for the activation and use of zero-valent metals in synthesis nature.com/articles/s44160-0… ($)
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Excited to share that Rob and Sarah's work on using PID-controlled jar heaters for #ballmilling - and application to #extrusion - enabling mechanochemical cross coupling is now available on @ChemRxiv! collab with @Syngenta 🦾♨️@ucl @School_Pharmacy chemrxiv.org/engage/chemrxiv…
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This one is open access 🔓 Don't miss 'Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis' by @DuncanLBrowne, @JamieLeitch165, @RRBolt97, @AJOrgChem, and @WillNicholson18 Read the Tutorial Review here 🔗 rsc.li/3wM5ow3

Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis

Rapid and wide-ranging developments have established mechanochemistry as a powerful avenue in sustainable organic synthesis. This is primarily due to uniqu

pubs.rsc.org
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Just out in #OL, Morrill and coworkers report the electrochemical deconstructive functionalization of cycloalkanols via alkoxy radicals enabled by PCET. Please have a look: pubs.acs.org/doi/10.1021/acs… @MorrillGroup @ChemistryCU @BrownGroup @School_Pharmacy
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My contract at Cardiff comes to an end in July. Does anyone have a job for me? 😊 #chemtwitter
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Andy Jones retweeted
Domainex@Domainex_UK28 Apr 2022
In our latest "Synthesis in Review" blog, we have featured some useful new synthetic transformations. We hope you find it interesting. domainex.co.uk/news/synthesi… #Domainex #DrugDiscovery #SyntheticChemistry #MedChem
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Andy Jones retweeted
Domainex@Domainex_UK28 Mar 2022
#Domainex is delighted to welcome Andrew Jones to our #chemistry team. Andy has recently completed his PhD in synthetic organic chemistry at Cardiff University focussing on the development of mechanochemical techniques. #DrugDiscovery #ScientificCareers #SyntheticChemistry
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PhD students: Each time you sit down to craft a figure, write a sentence, or work on a paragraph, you make a small deliberate step towards advancing the frontier of human knowledge. Your time is valued, and your effort will compound over time. #PhDchat #AcademicTwitter
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Andy Jones retweeted
Koji Kubota@k0j1chem18 Nov 2021
Our paper on mechanochemically prepared Grignard reagents is finally out now in @NatureComms!! Congrats @rina_chemistry, @haj19932469 and the team! Great collaboration with Prof. Maeda @SatoshiMaeda15, Prof. Jiang and Prof. Takaya! nature.com/articles/s41467-0…
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Congratulations to James and @DeepMishr, whose work on the electrochemical oxidative Z-selective C(sp2)–H chlorination of acrylamides has been published in @ChemCommun as part of the 2021 Emerging Investigators themed issue pubs.rsc.org/en/content/arti…

Electrochemical oxidative Z-selective C(sp2)–H chlorination of acrylamides†‡

An electrochemical method for the oxidative Z-selective C(sp2)–H chlorination of acrylamides has been developed. This catalyst and organic oxidant free met

pubs.rsc.org
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My work looking into mechanochemical cross-electrophile coupling with @WillNicholson18, @JamieLeitch165 and @DuncanLBrowne is now online at #OL @JOC_OL. #mechanochemistry pubs.acs.org/doi/pdf/10.1021…
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New Publication: Really happy about my new paper working with fluoroiodane for synthesis of novel heterocycles, and a huge thanks to Dr. Alison Stuart and Dr. Will Riley for an enjoyable collaboration. Online now at @ChemCommun pubs.rsc.org/en/content/arti… #mechanochemistry

Accessing novel fluorinated heterocycles with the hypervalent fluoroiodane reagent by solution and...

A new and efficient strategy for the rapid formation of novel fluorinated tetrahydropyridazines and dihydrooxazines has been developed by fluorocyclisation

pubs.rsc.org
Browne Group UCL@BrowneGroup14 Jun 2021
A big day for Andy (@AJOrgChem) as his work on fluorocyclisations is also online at @ChemCommun. This work was in collaboration with Dr. Alison Stuart and Dr. William Riley at Leicester University. @Leicesterchem. #mechanochemistry pubs.rsc.org/en/content/arti…
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