Post doc at the University of Calgary interested in neurovascular coupling. Musician. Family man.
Joined April 2020
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Adam Institoris retweeted
Pleased to share our new paper implicating #interleukin 10 in perturbed #brain #microcirculation and #cognitiveimpairment in mouse model of type 1 diabetes. Congrats to the team @uvic, @sharmasorabh88, @UVicMedSciences, @NatMetabolism, nature.com/articles/s42255-0…
Adam Institoris retweeted
🚨 Our work on neurovascular coupling and CO2 is online in @NatureComms 🥳
nature.com/articles/s41467-0…
Great work from the @JillStobart lab! They discovered a novel function of astrocyte NMDA-receptors. Congrats!
Big news!! Our paper about astrocyte NMDA receptors is out in Nature Communications! rdcu.be/dzcE9
This team effort was spearheaded by @NoushinAhmadpo1 @MeherKantroo
Thanks to the Reviewers for suggesting "mechanism" experiments that took this story to the next level!
Adam Institoris retweeted
Curious about how astrocytes regulate cerenbral blood flow? And all the perplexing findings, unanswered questions, and directions for future research?
Check out this new chapter, in collaboration with Grant Gordon, @brian_macvicar and Eric Newman.
tinyurl.com/yxxdzh4j
A thought provoking review on astrocytes in @NatureNeuro by @Ciaran_MR. A must read!!
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Such an important line of research!
It's out! The 1st paper of the lab on gut barrier led by the talented @elldonee in @BiologicalPsyc1 GOS 🥳🥂
Sex-specific impact of stress on the gut tight junctions, microbiota and we identified LBP as a gut/🩸 biomarker of stress 🐭 and depression 🙋🏻♀️
sciencedirect.com/science/ar…
Adam Institoris retweeted
Pharmacology and imaging of pericytes expressing GCaMP6f uncovers the basis of Ca2+ signaling in mid-capillary brain pericytes. @Rungtalab nature.com/articles/s42003-0…
Adam Institoris retweeted
Can’t wait to see you THIS THURSDAY 12PM PT/ 3PM ET for another great set of talks featuring @CDMorrone and @milene_vandal zoom link below 👇
ucalgary.zoom.us/j/963829061…
Adam Institoris retweeted
But wait! There's more! @milene_vandal of @UCalgary will be presenting her work. Don't miss out 🇨🇦ucalgary.zoom.us/j/963829061…
Adam Institoris retweeted
#Astrocytes are hard to image accurately using light microscopy due to their convoluted maze of fine branches.
Our paper was featured on the Editor's highlight page in Nature Communications. Check it out if you haven't already!
nature.com/collections/mjkks…
Adam Institoris retweeted
Did you know that astrocytes express NMDA receptors? In our latest work, we show how these receptors regulate astrocyte calcium events and optimize neuronal activity for sensory discrimination.
A brief summary of our preprint: biorxiv.org/content/10.1101/…
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Adam Institoris retweeted
We are hiring a postdoctoral fellow to study mechanisms of brain microvascular dysfunction in aging and Alzheimer’s disease, using state-of-the-art in vivo multiphoton microscopy and transgenic mouse models. careers-seattlechildrens.ici…. More about the lab: theshihlab.com/
Our paper is out!
nature.com/articles/s41467-0…
With genetic Ca2+ clamping and chemogenetic activation of astrocytes, we show that astrocytes enhance neurovascular coupling when neuronal activation is sustained but not when activation is brief.
A great team effort by Grant Gordon's lab, including @milene_vandal, @peringod and collaborators: @xinzhu_yu, @baljit_khakh, @neurophy and others.
Very exciting findings by @Ciaran_MR with @AdedipeIfe and @Holt_LewisRhys on how astrocytes mediate cognitive and behavioural defects in adolescence induced by early-life stress. The astrocyte GR-knockout experiments are awesome!
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Adam Institoris retweeted
Astrocyte Cafe is happy to announce that Chris Dulla @DullaChris and Christabel Tan @xbel_tan will be presenting on coming Thursday, the 15th of December! 🤩🤩
Adam Institoris retweeted
Come to the Cajal course on Neurovascular Function next year! Great speakers e.g. @AndyShih_Lab @NelsonLab1 @MartinMlauritz @SusanneVanVeluw @DalkaraLab! Learn amazing experiments with people like @AxL_Montagne @nvc_sheffield @bethsbrainbites! Experience Bordeaux 🍷!
Adam Institoris retweeted
Check out our new paper in @CellReports where we image pathological chloride microdomains and swelling in dendrites using FLIM.
cell.com/cell-reports/fullte…
