Former president of @FIEathletecom, ex fencer for @fencingireland Chairman of @difcricket, NK cell and dendritic cell biologist @KarolinskaInst

Joined October 2015
Congratulations to @karolinskainst biomedicine student Daniel Langdon who won poster prize at @ASP_GPO @AmgenFoundation symposium in @Cambridge_Uni
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Benedict Chambers retweeted
New work from our group and Kim Thrane's resolving the immune phenotype of sinonasal cancer with TCR/BCR profiling in tissue sections. SNC are sky-high for Treg cells and Treg clones colocalise with CD8 T and B cells in CXCL9+ niches. #spatialVDJ #scRNASeq biorxiv.org/content/10.64898…
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And this why boys and girls you need to know the reagents that you are using
Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a completely wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins 🧵
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Benedict Chambers retweeted
So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB
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Our paper on JAML and NK cells on bioRxiv now Thanks to @Cancerfonden for supporting this work
Intratumoral expression of JAML on NK cells is controlled by tumor microenvironment and MHC class I interaction biorxiv.org/content/10.64898… #biorxiv_immuno
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NK50 meeting @karolinskainst some of the greatest minds in #nkcells and me
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Opening of @ASP_GPO @AmgenFoundation first day at @Cambridge_Uni for the European symposium 2025….the Karolinska cohort will present their findings today
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Poster putting up time for 2025 @AmgenFoundation Karolinska scholars
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The MDV Lab is hiring! We have a Research Assistant position (part time) to characterize EBV virus-specific T cells in people with multiple sclerosis, funded by the @mssocietyuk. imperial.ac.uk/jobs/search-j… Come work with us! Please feel free to share.
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Benedict Chambers retweeted
There are now >550 inborn errors of immunity 🧬. Latest update from IUIS IEI c’tee is now available on IUIS website & will be formally published soon. Great to be part of this team providing an important resource for all. Well done @IsabelleMeyts @cecipolih & all ctee members!
The 2024 IUIS Inborn Errors of Immunity (IEI) Classification has arrived! Explore our latest insights now at iuis.org/committees/iei. Find the report under “Annual 2024 Report”!
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Benedict Chambers retweeted
For the first time in 5 years Covid is relatively quiet during the holiday season. The XEC variant marches on (latest CDC genomic surveillance below) slowly advancing as % of attributable cases. Fortunately, it's not one that poses a big challenge to our now conditioned immune response covid.cdc.gov/covid-data-tra…
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Is that the coward @Jeff_Mold going to face me?
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Time to prove two things 1) I am aging and 2) I am still a fencer! Hetting ready for veteran @FIE_fencing fencing champs @FIEAthleteCom
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Benedict Chambers retweeted
🚨🚨I’m excited to present our lab’s new paper where we tried to provide a mechanistic explanation for the link between antibiotic use and risk of developing inflammatory bowel diseases (#IBD). A 🧵/1 science.org/doi/10.1126/scia…
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I can confuse them in a far shorter time than a few weeks
This Post is from an account that no longer exists. Learn more
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Benedict Chambers retweeted
Sorry for maybe dumb question: you know how ppl differentiate iPSCs into all kinds of cells? Can they diff into cell types that don’t normally exist in nature?
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How much rent does Cambridge have to pay for this space in their lunch room? @karolinskainst @akademiskahus Time to reduce rents in academia in Sweden to better Swedish science
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Great night last night in Cambridge with @DrFran_Colucci, made better by randomly meeting an @karolinskainst Amgen scholar from 2014 as the 2024 cohort also randomly was walking by…..a 10 year generation gap but still the same excitement @ASP_GPO @AmgenFoundation
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Welcome to @Cambridge_Uni #AmgenScholars Prof. Alex Webb kicks off the day, reminding Scholars that contrary to how scientists are often depicted in films, with the lone scientist in a lab, science is a team endeavor
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Final day presentations for the @karolinskainst Amgen scholars after their 8 weeks @AmgenFoundation @ASP_GPO @AmgenScholarECC
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