Alison Forrester (@AlisonForreste3) header
Alison Forrester (@AlisonForreste3) profile picture

Alison Forrester

@AlisonForreste3

ER, trafficking & microscopy aficionado. Group leader @frsFNRS @WELRI_asbl @UNamur (Belgium)

 Namur, Belgium
Joined September 2019
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Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)Photo by Alison Forrester (@AlisonForreste3)
I'm excited to see our work online! EGF regulation of clathrin-independent endocytosis, via an elegant pH sensitive mechanism. Thank you to all for making it a great project to work on! #AcademicTwitter nature.com/articles/s41556-0… @institut_curie @EwanMac10292433 @CessVala @3i_inc
Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis

Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis

Nature Cell Biology - MacDonald et al. show that EGF triggers de-sialylation of plasma membrane glycoproteins like integrins in a mechanism that depends on the Na+/H+ antiporter NHE1 and the...

nature.com
Ewan MacDonald (@EwanMac10292433) profile pictureEwan MacDonald@EwanMac1029243322 Feb 2025
Thrilled to share our latest publication! We describe a novel acid-dependent mechanism regulating clathrin-independent endocytosis. This study was a fantastic collaborative effort with the labs of Ludger Johannes, Roberto Weigert, and Satyajit Mayor. nature.com/articles/s41556-0….
Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis

Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis

Nature Cell Biology - MacDonald et al. show that EGF triggers de-sialylation of plasma membrane glycoproteins like integrins in a mechanism that depends on the Na+/H+ antiporter NHE1 and the...

nature.com
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Cesar VALADES-CRUZ (@CessVala) profile picture
Cesar VALADES-CRUZ@CessVala22 Feb 2025
Happy to contribute to the analysis of β1integrin endocytosis using @3i_inc LLSM, now in @NatureCellBio rdcu.be/eaLM9 @LeconteLudovic C. Wunder @AlisonForreste3 @JeanSalamero @EwanMac10292433 Johannes team @institut_curie @Inria_Rennes @Fr_BioImaging #bioimageanalysis
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Going Green at the Dept Biology & Fac of Medicine @UNamur! We've worked on it for a year, now it's time to go big 😁💚🔬 It's great to see so much enthusiasm! @fsilvestrelab.bsky.social #sustainability #GreenLab
Image from Alison Forrester (@AlisonForreste3)
Image from Alison Forrester (@AlisonForreste3)
Image from Alison Forrester (@AlisonForreste3)
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Alison Forrester retweeted
maurizio molinari (@MolinariLab) profile picture
maurizio molinari@MolinariLab25 Oct 2024
Have a look at our latest review: Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes Including the Halo-GFP reporter and LysoQuant developed in our lab. onlinelibrary.wiley.com/doi/…
Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify...

Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify...

Our review reports on qualitative, quantitative, and chronological monitoring of lysosomal protein trafficking, and of autophagic and heterophagic fluxes to acidic, degradative endolysosomes. We...

onlinelibrary.wiley.com
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Gabriele Zaffagnini (@zaffagg3) profile picture
Gabriele Zaffagnini@zaffagg327 Sep 2024
🔊 #Job alert! We're #recruiting a #research #technician! We are looking for a reliable and motivated technician to support the lab operations, with the possibility to perform advanced experiments in autonomy and to collaborate to research projects. Your profile: - Biological Technical Assistant title (BTA, CTA, MTA) or equivalent. - Full working proficiency in German and English - Responsible, organized, and able to work independently. - Willing to work with mice. Experience in mice handling is desirable. DEADLINE: 13/10/2024 💼 Details: jobportal.uni-koeln.de/aussc… 📨 Apply: jobportal.uni-koeln.de/bewer… @CECAD_ @UniCologne
Image from Gabriele Zaffagnini (@zaffagg3)
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Had an awesome time at the Awesome Lysosome Meeting @Tigem_Telethon! Celebrating 30 years of TIGEM and Andrea Ballabio stepping down from role as director. Caught up with old friends and made lots of new (and VERY new!) friends! @franzappa2 @cristinasorr
Image from Alison Forrester (@AlisonForreste3)
Image from Alison Forrester (@AlisonForreste3)
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Gabriele Zaffagnini (@zaffagg3) profile picture
Gabriele Zaffagnini@zaffagg39 Sep 2024
📢 #Job Alert! #postdoc position available in my lab! You have experience in #cell #biology / #biochemistry and you wish to learn a novel way to organise the endolysosomal system? Then look no further! 👇🏼 We have a fully funded position for up to 5 years to study the regulation of endolysosomal super-organelles in mouse oocytes. Apply with a cover letter, CV and contacts of 2-3 academic references. Applications until 1.12.24 *only* through the following link: jobportal.uni-koeln.de/?max=… (ID: Wiss2409-06) Pls share and RT! @CECAD_ @UniCologne
Image from Gabriele Zaffagnini (@zaffagg3)
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Ishier Raote (@ishier_raote) profile picture
Ishier Raote@ishier_raote24 Jul 2024
Nice preprint from @sharontooze01! Lysosome damage triggers repair via ATG9A vesicles delivering PI4K2A, balancing lipid transfer and maintaining lysosome homeostasis after damage. ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair biorxiv.org/content/10.1101/…
Image from Ishier Raote (@ishier_raote)
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Reto Fiolka (@RetoPaul) profile picture
Reto Fiolka@RetoPaul17 Jul 2024
I still remember someone asking Ernst Stelzer if LSFM could image a whole mouse, and he said: "What a mouse?!" It was a rhetorical question in the early light-sheet days. But here we are.
Ali Max Erturk (@erturklab) profile pictureAli Max Erturk
@erturklab17 Jul 2024
What if we could map every cell in the body, revealing its location and molecular identity? In this @NatureMethods perspective, we discuss the new era of 3D-omics by tissue clearing and AI, called Deep 3D Histology: rdcu.be/dNBe8 PDF: bit.ly/3WaD0QU 🧵👇🏼
Image from Ali Max Erturk (@erturklab)
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As a proud Worcestershire-ite (? suggestions welcome) this one deserves a share. Available for pronunciation consultation.
No Context Brits (@NoContextBrits) profile pictureNo Context Brits
@NoContextBrits15 Jul 2024
Image from No Context Brits (@NoContextBrits)
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📊 Do you need to interpret complex and large-scale biomedical datasets? Our National Facility for Data Handling & Analysis is now available to the national scientific community! Find out how to access it here 👉 humantechnopole.it/en/facili… #datascience
National Facility for Data Handling & Analysis - Human Technopole

National Facility for Data Handling & Analysis - Human Technopole

The mission of the National Facility for Data Handling and Analysis is to support the national research community by providing state-of-the-art analysis of biological datasets generated by high-thr...

humantechnopole.it
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We are looking for an experienced light microscopy specialist to support the Advanced Light Microscopy Facility @embl Heidelberg: embl.org/jobs/position/HD026… - closing date 5 August 2024 @EuLiMI1 @EuroBioImaging @GerBI_GMB @Fr_BioImaging @GlobalBioImage @BioImagingUK
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Alison Forrester retweeted
maurizio molinari (@MolinariLab) profile picture
maurizio molinari@MolinariLab16 Jul 2024
Fellowship for PostDoc available
Image from maurizio molinari (@MolinariLab)
Image from maurizio molinari (@MolinariLab)
Image from maurizio molinari (@MolinariLab)
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Jonny Nixon-Abell (@AbellJonny) profile picture
Jonny Nixon-Abell@AbellJonny16 Jul 2024
🚨🔔🚨 We have another postdoc opening in our group to study lipid trafficking in neurons. If you have a background in mechanistic cell biology and lipids (lipidomics= bonus!) and are interested in employing your skills in neurons- Apply! Link below - closes 22nd July. please RT!
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Ishier Raote (@ishier_raote) profile picture
Ishier Raote@ishier_raote16 Jul 2024
Nice preprint! TANGO1 orthologues have been identified in all metazoans, except nematodes. Finally, the C. elegans TANGO1! Required for vitellogenin export from the ER. A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans. biorxiv.org/content/10.1101/…
A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans

A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans

Vitellogenin belongs to the Large Lipid Transfer Protein superfamily and is thought to share a common ancestor with human Apolipoprotein B (ApoB) for systemic lipid transport[1][1]–[5][2]. Vitellog...

biorxiv.org
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Sharon Tooze (@sharontooze01) profile picture
Sharon Tooze@sharontooze0116 Jul 2024
Last chance to register for an amazing double bill! Check out programs! events.faseb.org/event/phosp… and events.faseb.org/event/11b64… #Phospholipids #Lipiddroplets

Archived Event - Phospholipids in Aging and Disease

events.faseb.org
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Oliver Barnstedt (@obarnstedt) profile picture
Oliver Barnstedt@obarnstedt14 Jul 2024
🚨Pls retweet!🚨 Barnstedt Lab is going live at the University of Magdeburg! We have 2 fully-funded job openings to study the neural circuits of memory and action using in vivo optical tools. Come join us! 🔬🐭❇️🏃💭 Postdoc: ovgu.b-ite.careers/jobpostin… PhD: ovgu.b-ite.careers/jobpostin…
Image from Oliver Barnstedt (@obarnstedt)
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Cell Biology J-Club (@cell_club) profile picture
Cell Biology J-Club@cell_club11 Jul 2024
Short transmembrane domains target type II proteins to the Golgi apparatus and type I to the endoplasmic reticulum journals.biologists.com/jcs/…
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Amra Sarić (@SaricAmra) profile picture
Amra Sarić@SaricAmra12 Jul 2024
Cells sense high lysosomal membrane tension - as can happen in some lysosomal storage disorders - and activate transcriptional programs to help tissues deal with this stress. Huge congratulations to @RuiqiCai @spencerSK1 and others! rdcu.be/dNyYD
Image from Amra Sarić (@SaricAmra)
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We have updated our manuscript characterising the function of ARF1 compartments in human cells which we believe are the masters of Clathrin-dependent post-Golgi trafficking! 🧵 biorxiv.org/content/10.1101/…
ARF1 compartments direct cargo flow via maturation into recycling endosomes

ARF1 compartments direct cargo flow via maturation into recycling endosomes

Cellular membrane homeostasis is maintained via a tightly regulated membrane and cargo flow between organelles of the endocytic and secretory pathways. Adaptor protein complexes (APs), which are...

biorxiv.org
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