@AndrewNChang
Joined March 2022
  • Tweets7
  • Following22
  • Followers8
Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs @ColumbiaBiochem reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online @CellCellPress! sciencedirect.com/science/ar…
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Andrew Chang retweeted
Structure@Structure_CP8 May 2025
Online now! Structural basis of human uromodulin filament networks in uropathogen capture dlvr.it/TKdsLM

Structural basis of human uromodulin filament networks in uropathogen capture

Uromodulin filaments can self-assemble into filament lattices to facilitate uropathogen capture and elimination. Chang et al. determine the cryo-EM structures of uromodulin filament lattices,...

cell.com
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Andrew Chang retweeted
Cell@CellCellPress7 May 2025
Now online! The structure of human sweetness dlvr.it/TKd5XK

The structure of human sweetness

A single taste receptor initiates our reactions to both sugars and artificial sweeteners, triggering a signaling process that drives our intense attraction to sweet foods. Single-particle cryo-EM...

cell.com
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Many congratulations @andrewnchang on being co-awarded the ('23) prize for most outstanding biological research by a graduating senior: tinyurl.com/e2k33bs8 He joins @FitzpatrickLab alums @tamtaarakhamia ('22) & @christinalee587 ('21) as recipients of this prestigious award.
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Andrew Chang retweeted
Cell@CellCellPress8 Mar 2022
Now online! Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases dlvr.it/SLJFTF

Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases

Cryo-EM and mass spectrometry-based proteomics of insoluble amyloid fibrils derived from postmortem human brains afflicted with diverse neurodegenerative diseases reveals widespread fibrillization of...

cell.com
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A protein normally involved in clearing cells of molecular debris can clump into fibrils, potentially hobbling cells, says a new study by @ZuckermanBrain's @FitpatrickLab. @CellCellPress bit.ly/3hEqUvF
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Many congratulations to our three undergraduate co-first authors @andrewnchang @m_simjanoska @tamtaarakhamia @CC_Columbia @allhailkylin @StanfordBiosci @JingWang0610 @carolynlinlee on the latest paper from @FitzpatrickLab, online now @CellCellPress! See: tinyurl.com/2wn5cwt6
Marija Simjanoska, Andrew Chang, and Carolyn Lee in the Fitzpatrick lab at the Zuckerman Institute, Columbia University, New York City, New York and former Fitzpatrick lab member Xinyu Xiang now at Stanford University, Stanford, California.

ALT Marija Simjanoska, Andrew Chang, and Carolyn Lee in the Fitzpatrick lab at the Zuckerman Institute, Columbia University, New York City, New York and former Fitzpatrick lab member Xinyu Xiang now at Stanford University, Stanford, California.

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