Molecular virologist | Deep-sequencer | Institute Investigator @scrippsresearch | Co-founder and CSO @clickseqtech | 🇬🇧 in 🇺🇸 | He/him | Dad
Davis, CA
Joined May 2011
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Andrew Routh retweeted
1st preprint of 2025: doi.org/10.1101/2025.01.09.6…. Now you can use "PT-ClickSeq" to sequence viral particles directly without RNA extraction! We demonstrate that FHV genome release in a programed step-wise fashion! @clickseqtech @AndrewRouth
Andrew Routh retweeted
A new preprint from our collaboration with @AndrewRouth on #sarscov2 recombination.
Led by @TommyGottaGO & Yani, we found that SARS2 is more recombinogenic than other human CoV. We also find a key role for NSP15 EndoU activity in shaping recombination.
tinyurl.com/23a9vwvb
Andrew Routh retweeted
My department is hiring a tenure-track faculty focusing on RNA biology!
@UCIrvine has a large, vibrant and super supportive RNA community! Come join us!
recruit.ap.uci.edu/JPF09320
Andrew Routh retweeted
ClickSeq, Poly(A)-ClickSeq and X-ClickSeq kits are now available!
At @clickseqtech, we are delighted to be working with baseclick (baseclick.eu/) to bring #ClickSeq kits to the broader market!
clickseqtechnologies.com/kit…
ClickSeq: random-primed, fragmentation-free RNAseq or DNAseq
Poly(A)-ClickSeq: 3'-end focused RNAseq for gene expression and polyadenylation analysis
X-ClickSeq: for customized, targeted NGS with user-provided primers
Simple, affordable Next-Generation Sequencing, powered by Click-Chemistry!
Perfect for researchers looking to streamline their next-generation sequencing workflows, these kits ensure reduced artifacts and enhanced precision.
ClickSeq and Poly(A)-ClickSeq kits are now available!
At @clickseqtech, we are delighted to be working with baseclick (baseclick.eu/) to bring #ClickSeq kits to the broader market!
clickseqtechnologies.com/kit…
The expertise and distribution capabilities of baseclick (baseclick.eu/) are crucial in making these technologies accessible to researchers worldwide.
Andrew Routh retweeted
Excited to share our latest manuscript on virus maturation!
We've successfully solved the structures of five intermediates in the NωV maturation process and unraveled the intricate structural reorganization required for infection.
biorxiv.org/content/10.1101/…
Andrew Routh retweeted
A new manuscript from the lab by graduate student @LVSoles ! 🧵
A nuclear RNA degradation code for eukaryotic transcriptome surveillance biorxiv.org/content/10.1101/…
Andrew Routh retweeted
New study just out in @MolecularCell by @Wagnerlab_RNA and Liang Tong using #ClickSeq for RNAseq/gene expression analysis:
"Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function"
cell.com/molecular-cell/full…
Andrew Routh retweeted
JOB: Advance our understanding of the epidemiology and evolutionary dynamics of foot-and-mouth disease virus (FMDV) at regional and global scales.
Apply for the role of Postdoctoral Scientist ➡️ow.ly/wWrJ50SvsbN
ALT Darkened image of cattle sits behind pink hexagon containing white text that reads "Postdoctoral scientist; analyse fmdv sequences and outbreaks; location Woking; salary range £38,500 to £40,000; closing date 18 July 2024." In the bottom right corner is a white version of the pirbright institute.
Andrew Routh retweeted
Ecstatic to share the peer-reviewed version of our manuscript revealing how the human coronavirus HKU1 recognizes the TMPRSS2 host receptor!
Led by @Dr_MattMcCallum & @YoungjunPark11
@HHMINEWS
@UWBiochemistry
cell.com/cell/fulltext/S0092…
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Andrew Routh retweeted
Job Posting:
Bioinformatics Core Manager at the UC Davis Genome Center
recruit.ucdavis.edu/JPF06481
Andrew Routh retweeted
Examining the evolution of the RNAi/piRNA pathways in vectors and different #virus infections is important. A small paper in @InsectMolecBio examines the siRNA response in sandfly cells against the flock house virus. resjournals.onlinelibrary.wi…
Andrew Routh retweeted
We're starting to recruit postdocs to work on this exciting ERC (now UKRI) project. Please get in touch if you would like to join us, or spread the word. #phosphatases #redox #Tcells @SFRR_Europe @ListerInstitute @EMBO_YIP
NEWS | Congratulations to Dr Hayley Sharpe @Sharpe_Lab @EMBO_YIP on the award of her @ERC_Research Consolidator grant to study the unsolved mystery of T cell signalling.
ALT Inset image of Dr Hayley Sharpe, set over a false-coloured image of phagocytic primary macrophages expressing a fluorescent reporter to detect cellular hydrogen peroxide production (shown by yellow/orange colouring). Text reads: News - Dr Hayley Sharpe receives an ERC Consolidator Grant
What a wonderful conference! #SocialViruses here in Puerto Rico.
Awesome science.
Awesome location.
Awesome people.
So many thanks to @AsherLeeks and @sociovirology for another success!
Andrew Routh retweeted
Yesterday ironing out some last minute details with @AsherLeeks over frituras and drinks. Today we kicked off with a fun mixer. Excited for the next couple of science-packed days! #PuertoRico #SocialViruses #LoveVirology
Andrew Routh retweeted
The Social Lives of Viruses Meeting, tropical edition, is starting in just a few days! #PuertoRico #SocialViruses #LoveVirology
Announcing the Social Lives of Viruses 2024!
Do you study social evolution in viruses? Do you want to?
Join us in Puerto Rico this June for a 50-person meeting dedicated to viral sociality. All costs covered.
Apply here: forms.gle/sHTEcHJjryDhHqZu9
#LoveVirology
#SocialViruses
Andrew Routh retweeted
The Research Scholars Program in Insect Biology aims to provide undergraduates with mentored research experience. The program offers undergraduates research experience that cultivates students’ skills for careers in biological research. Learn more: ucdav.is/4bYNFEv