Vice Chair Faculty Affairs at Penn Cardiothoracic Anesthesiologist and Intensivist

Philadelphia, PA
Joined September 2018
Milrinone versus Epinephrine After Cardiac Surgery: Does the Choice Matter? An interesting retrospective, entropy-balanced cohort study published in JCVA compared postoperative outcomes in 1,310 cardiac surgery patients receiving milrinone (n = 312) or epinephrine (n = 998) as the initial inotrope. Key findings: No statistically significant difference in 90-day mortality (7.1% vs 6.6%). Milrinone was associated with higher rates of acute kidney injury (73% vs 61%) and renal replacement therapy (13% vs 7.6%). ICU and hospital stays and time in postoperative organ dysfunction were longer with milrinone. However, these findings warrant cautious interpretation. The retrospective design, potential confounding by indication, unavailable intraoperative variables, and differences in treatment duration limit causal interpretation. The findings raise important questions but do not establish the superiority of either inotrope. Randomized trials are needed. Peiris et al. J Cardiothorac Vasc Anesth. 2026. doi.org/10.1053/j.jvca.2026.… @JCVAonline @BJAJournals @JournalofClinAn @SCVA1997 @SRAnesthesiaICU @IARS_Journals @escardio @ASA_Australia @scahq @scahq_tas @ITACTAtwits @actacc @sedar_es @Siaarti_online @EACTS @ESAICTraineeN @ESAIC_org @EACTAIC @MattersoftheH14 @Assoc_Anaes @ASALifeline @STS_CTsurgery @Mansoura_un @AugoustidesJohn @JkaplanJoel @jiapenghuang @IAU_KFHU @Med_iau
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Cut it out! In obstructive HCM, adding surgical cutting of thickened, retracted secondary chordae of the anterior mitral leaflet to septal myectomy delivered excellent long-term clinical & hemodynamic results. #JACC @A_sorropago More: bit.ly/4zjCAKF
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#JACCCEP study: A combination of atrial #Cardiomyopathy markers was linked to high #AFib prevalence in endurance athletes. A resulting quantitative AFib risk ID tool gives promise for interventions aimed at preventing AFib & thromboembolic complications. bit.ly/4siJWeu
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#Vasoplegia30 Vasoplegic Syndrome After Cardiopulmonary Bypass: Refining Recognition... sciencedirect.com/science/ar…
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#ASA26Panel We highlighted a multimodal therapeutic approach Thanks to all
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#JACCCardioOnc review: 🫀 Anthracycline cardiotoxicity: more than cardiomyocyte damage! 🔬 Emerging evidence reveals a key role for immune activation, inflammation, & fibrosis. 🎯 Could immune recalibration reshape cardioprotection? @Massimi78530343 bit.ly/47rbc0S
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The 2026 Multisociety Acute Pulmonary Embolism Guidelines: An Expert Perspective 🫁 Acute pulmonary embolism assessment gains a five-category severity framework, including normotensive shock and a respiratory modifier. DOI: doi.org/10.1053/j.jvca.2026.…
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Excellent #ANES26 panel “You Gave What?!? New Drugs in #OBAnes” including @PennAnesthesia Dave Berman. Fun fact- who knew sugammadex and Febreze share a cyclodextrin core structure??
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2026 AHA/ACC/ESC/WHF Second Universal Definition of #HeartFailure is here! What’s changed in how we define and classify HF? Read here: bit.ly/4vEE7Ji #JACC #CardioX @ACCinTouch @AHAScience @escardio @worldheartfed
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Cardiogenic shock might be caused by multiple etiologies potentially deserving tailored management. A new clinical consensus paper focuses on the use of temporary mechanical circulatory support in acute myocardial infarction complicated by shock. doi.org/10.1093/eurheartj/eh… #EAPCI #ACVC #cardiotwitter, @ESC_Journals @escardio
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Engaging #OBAnes Fireside Chat discussion. Awesome to see @PennAnesthesia visiting professors opine about handling difficult conversations on labor & delivery! #ANES26
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Check out this #ANES26 session at 12:30 PM. Awesome meeting these energetic young panelists from across the country discussing #LanguageAccess
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Transseptal #TMVR with the SAPIEN M3 system among patients with symptomatic MAC-related MVD was associated with sustained #vhdMR reduction and improved symptoms and quality of life at 1️⃣ year, according to a new study in #JACC. Learn more: bit.ly/4zxKyPI
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The 2026 ACC Expert Consensus Decision Pathway on Management of Heart Failure With Preserved Ejection Fraction is here! What’s new in #HFpEF management? Read here: bit.ly/4hu2fdb #JACC #CardioX
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John Augoustides retweeted
The 2026 ACC Expert Consensus Decision Pathway on Management of Heart Failure With Preserved Ejection Fraction is here! What’s new in #HFpEF management? Read here: bit.ly/4hu2fdb #JACC #CardioX
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