BeGenomics is a comprehensive platform for Bioinformatics, Genomics, Epigenomics and Metagenomics.
England, United Kingdom
Joined December 2016
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BeGenomics retweeted
NIH researchers have discovered a natural defense mechanism that may help the body prevent plaque from building up inside arteries, opening new possibilities for treating atherosclerotic cardiovascular disease, a leading cause of death in the U.S.
BeGenomics retweeted
New @Cell_Metabolism on benefit of intermittent fasting in overweight individuals with metabolic syndrome
A randomized trial showed that the Mediterranean diet, while reducing lipid abnormalities, did not suppress inflammation until intermittent fasting was added
cell.com/cell-metabolism/ful…
BeGenomics retweeted
In 100% agreement
Exercise should be a prescribed
New @JACCJournals @ACCinTouch scientific statement
jacc.org/doi/10.1016/j.jacc.…
BeGenomics retweeted
Diet-microbiome interactions enhance cancer immunotherapy in obesity dlvr.it/TVvPzS
BeGenomics retweeted
The personalized neonantigen vaccines to treat cancer, already shown to work in malignant melanoma, and in trials of pancreatic cancer, glioblastoma, renal cell cancer, and triple-negative breast cancer.....now ovarian cancer. Results from a Phase 1 trial
nature.com/articles/s41591-0…
BeGenomics retweeted
Glutamine metabolism keeps pathogenic hepatic CD4+ T cells in check dlvr.it/TVvtDs
BeGenomics retweeted
Lactate couples metabolic state to necroptosis across pathological and physiological conditions dlvr.it/TVv4qM
BeGenomics retweeted
The risk of developing Alzheimer's disease in APOE4 carriers (~20% of the population) is influenced by brain DNA methylation @NatureAging
nature.com/articles/s43587-0…
BeGenomics retweeted
Glutamine metabolism as a rheostat of CD4+ T cell pathogenic function in metabolic dysfunction-associated steatotic liver disease dlvr.it/TVtSz8
BeGenomics retweeted
Engineering T cells for immunotherapy vs cancer had already had marked success in certain types. But there's a next generation in the hopper, as reviewed today @Cancer_Cell, that ought to help take the field much further into solid tumors
cell.com/cancer-cell/fulltex…
BeGenomics retweeted
Not all apoB-containing particles tell the same story.
🔹 Non–Lp(a) apoB → greater coronary plaque burden
🔹 Greater relative Lp(a) contribution → more vulnerable plaque features
New in #EJPC: Balance between apoB and Lp(a) may add another layer to cardiovascular risk assessment and personalized prevention. ow.ly/uL2650ZWCIC
@EJPCEiC @AboyansV @SilCastelletti @PTBuketAkinci @PeroneFrancesco @SMosteoru @TimKambic
BeGenomics retweeted
A seminal paper on aging of our immune system was just published. From study of over 12 million single-cells in 8 cohorts, >2,600 individuals, ranging in age from 18 to 98. Yielding a practical blood test. And much more.
A Tale of Two T cells
In the new Ground Truths
BeGenomics retweeted
Immunometabolic endotypes define distinct clinical trajectories in type 2 diabetes dlvr.it/TVqljJ
BeGenomics retweeted
Why do small dogs live longer than large dog species, and what is the biologic basis of differences in lifespan and healthspan?
Epigenetics.
There's a lot in the methylation pattern of dogs to explain this @ScienceMagazine
science.org/doi/10.1126/scie…
BeGenomics retweeted
Unfortunately, the medical community has a singular view of the basis of coronary artery disease—lipids. But we keep seeing ways that heart attacks can occur independent of any lipid abnormality, like this one
New @CellCellPress
cell.com/cell/fulltext/S0092…
BeGenomics retweeted
Good summary statement and evidence review of optimal diet and nutrition
@JACCJournals
jacc.org/doi/epdf/10.1016/j.…
BeGenomics retweeted
Central adiposity and systemic inflammation partially mediate the association between ultra-processed food consumption and #CVD risk, according to a study published in #JACCAdvances.
Get full details ➡️ bit.ly/3UaG1DT #CardioX
