Thoracic oncologist at UT Southwestern Medical Center (@utswcancer), studying small cell lung cancer. Tweets are my own.
Joined January 2013
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1/ Excited to share our new paper with @SihanSean @utswcancer @CRI_UTSW and Michael Lawrence @MGH_RI, now online @CD_AACR. Led by Shreoshi Pal Choudhuri, we found that ecDNAs with MYC paralogs drive acquired cross-resistance in small cell lung cancer #SCLC
aacrjournals.org/cancerdisco…
7/ We conclude that ecMYC/L/N are recurrent drivers of cross-resistance in SCLC. Shreoshi led a team effort from @jillianmcwise Dr. Luc Girard @stanleylim93 @Hfarsibaf @MarcelloStanzi1 @cbmeador, and many others without twitter handles.
8/ We are grateful to the patients who participated in this research, to @MGHThoracicOnc, and to our funding. This project was launched with @AnnaFaragoMD, guided by Nick Dyson, and inspired by Bruce Johnson, Adi Gazdar and John Minna, who figured most of it out in the 1980's.
