Postdoc at Genome Instability and mammalian physiology, @George_Garinis lab, @IMBB_FORTH.
Heraklion, Greece
Joined November 2023
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Reverse transcriptases challenge the central dogma of biology, again: Cell cell.com/cell/fulltext/S0092…
Callina Stratigi retweeted
🧬🧬🧬It’s all in your DNA: damage in the DNA accumulates and drives aging. Could mending damaged DNA prolong life? News featuring the DREAM master regulator of DNA repair today in @Nature nature.com/articles/d41586-0…
Callina Stratigi retweeted
Online now!✨RESEARCH: Niotis, Arvanitaki et al identify DNA damage induced autophagy in macrophages as a link from aging to autoimmunity nature.com/articles/s43587-0…
Callina Stratigi retweeted
Telomeres are transcribed into TERRA. We showed that iTERRA is transcribed from interstitial telomeric repeats (ITSs) and that CpG island subtelomeric promoters are also present at interstitial sites bit.ly/4oD0UBH
Callina Stratigi retweeted
Attenuation of ATM signaling by ROS delays replicative senescence at physiological oxygen dlvr.it/TPyXzf
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Defective RNA processing and ELOA-mediated transcriptional elongation in reversible cellular senescence suggest aging by transcription dlvr.it/TPvv56
Callina Stratigi retweeted
Glycolytic diversity drives immune complexity in cancer dlvr.it/TPZJVd #immunology
Callina Stratigi retweeted
Online Now: Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress dlvr.it/TPSsD7
Callina Stratigi retweeted
Online Now: A role for human senataxin in contending with pausing and backtracking during transcript elongation dlvr.it/TPDN4H
Callina Stratigi retweeted
In the latest issue! Regulation of inflammatory responses by pH-dependent transcriptional condensates dlvr.it/TNSQwp
Callina Stratigi retweeted
And now for something completely different in co-translational targeting dlvr.it/TNTx4Z
Callina Stratigi retweeted
A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation dlvr.it/TMv8rD
Callina Stratigi retweeted
Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex dlvr.it/TMcnHP
Callina Stratigi retweeted
Check out our latest review, published in BioEssays, on how DNA damage triggers secretory responses that drive aging across tissues and the potential ways to delay systemic decline.
Read it here: onlinelibrary.wiley.com/doi/…
A big thank you to @EMBO and @embl for this great opportunity to meet and collaborate with amazing scientists in the ageing field #EESAgeing So proud of Sakis for presenting his work! @athsmt @George_Garinis
Callina Stratigi retweeted
Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵:
Callina Stratigi retweeted
Excited to share our findings in @NatureComms. We have expanded our understanding of telomere maintenance and genome stability through the RECQ4-MUS81 interaction, shedding light on its potential role in disease development. #GenomeStability
muni.cz/go/186ece
Callina Stratigi retweeted
Our next GiiN webinar will feature Lumír Krejčí from @muni_cz and Giulia Bastianello from @IFOMresearch. Join us on Tuesday, February 4th from 5-6 PM Rome Time for a lively discussion on genome integrity maintenance here: uniroma1.zoom.us/j/951499844…
Callina Stratigi retweeted
🔔 Our Special Issue, Transcription: Friend or foe of genome stability, is now online! 🧬
🖊️ Guest edited by Emmanuel Compe and Donata Orioli
➡️febs.onlinelibrary.wiley.com…
Ten reviews explore the dual role of #Transcription on #Genome stability.
