PhD, Ghent University (@TeamDerave) • Football analytics 📊 Skeletal muscle fiber type composition research 🔬
Gent, België
Joined November 2019
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Does one biopsy cut it? Short answer: no. Find out the longer answer below 🧵👇
This thread is based on our new @japplphysiol paper, where we investigated human muscle fiber type composition variability by analyzing repeated biopsies. Lots of them.
journals.physiology.org/doi/…
Freek Van de Casteele retweeted
Proud to have our paper featured on the cover of the April issue of @Cell_Metabolism. It shows an exercise-induced degranulating mast cell releasing histamine. Thanks a lot for the design Emma @DrawImpacts.
Read the full story here: cell.com/cell-metabolism/ful…
@TeamDerave
Freek Van de Casteele retweeted
From @ugent @karolinskainst @uni_copenhagen @CasteeleFreek et al.: Does one biopsy cut it? Revisiting human muscle fiber type composition variability using repeated biopsies in the vastus lateralis and gastrocnemius medialis 💪
🔗ow.ly/WZAQ50UfizT
Freek Van de Casteele retweeted
Inter‐Individual Variability in Muscle Fiber–Type Distribution Affects Running Economy but Not Running Gait at Submaximal Running Speeds | dx.doi.org/10.1111/sms.14748
Freek Van de Casteele retweeted
-Does one biopsy cut it? Revisiting human muscle fiber type composition variability using repeated biopsies in the vastus lateralis and gastrocnemius medialis-
New in @japplphysiol by @TeamDerave - nice work!
journals.physiology.org/doi/…
Freek Van de Casteele retweeted
Glad this stuff keeps coming out.
The variability in 'fiber type' from each biopsy is quite large, so results should be interpreted with caution - probably explains much of the 'mixed results' that plagued the field for decades.
journals.physiology.org/doi/…
👏@WiApro et al.
Sidenote: although type I % is not considered a direct determinant of V02peak, a significant positive relationship is expected as type I fibers generally have a higher capillary density and greater oxidative capacity than type II fibers
It was a pleasure working on this with @TeamDerave, @eline_lievens, @ThibauxV, our Swedish 🇸🇪 collaborators @MobergPhD, @WiApro, @HorwathOscar, and biopsy master @RuudVanThienen. Many thanks to all of you🙏
Freek Van de Casteele retweeted
We used our single-fiber transcriptomics workflow to profile how individual human muscle fibers respond to exercise. Our results are out now in @AJPCellPhys, with thanks to @TeamDerave, @FWOVlaanderen and @ugent_fge (1/5)
journals.physiology.org/doi/…
