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Latest from the Clostridium difficile research community. Edited by @nataszahain

Perth, Western Australia
Joined August 2016
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A new antimicrobial peptide designed based on Clostridioides difficile IF1 shows broad-spectrum inhibitory activities against C. difficile and other bacterial strains. journals.asm.org/doi/10.1128…
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In @CIDJournal, Pablo Okhuysen, MD, FACP, FIDSA, and colleagues aim to confirm the superiority of ridinilazole over vancomycin on Sustained Clinical Response and recurrent CDI as reported in a Phase II Study. Read: idsajournals.link/2OufYh
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Friday Celebrations! Chenlin Hu, PhD and @GareyKgarey published a review of microscopy methods for C. difficile in Anaerobe! 🔬🦠 Check it out ⬇️⬇️ doi.org/10.1016/j.anaerobe.2… @AnaerobeSociety @UH_Pharmacy
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🌟And the publications keep coming!🌟 Check out our labs most recent work on ibezapolstat activity against MDR C. difficile strains ⬇️⬇️ doi.org/10.1128/aac.01621-23 TLDR: IBZ bactericidal activity was similar to the MIC and maintained in wild-type and non-susceptible strains. – at Houston, TX
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🆕️🔥Multicenter cohort study included adults with C. difficile infection @CIDJournal Vancomycin MIC >2 μg/mL in Clostridioides difficile was associated with decreased odds of 30-day sustained clinical response & lower 14-day initial cure rates #IDXposts academic.oup.com/cid/article…
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It's not just about age anymore. #Clostridioidesdifficile infection is reaching beyond traditional risk groups. #guthealth #Cdiff
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Clindamycin attacking the normal flora 🥊 teapawt.org/Yoda4ever/status/17430…
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Have you seen this new @AmCollegeGastro monograph on microbiome therapeutics? ✅ Essential aspects of methods for analyzing the microbiome ✅ Present and future therapeutics for C. difficile ✅ Non-prescription therapeutics 👉 journals.lww.com/ajg/toc/202…
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New findings shed light on the key #microbes that protect against recurrent #Clostridiodes difficile infection and #MultipleSclerosis, pointing to future treatment opportunities with live #biotherapeutics. Read more: mshs.co/3Q9ZZdH #Immunology
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Happy to share the latest preprint from the @StadtmuellerLab - an incredible effort by recent PhD student @Sonya31397350! Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile biorxiv.org/content/10.1101/…
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C. Diff: Professors Suggest Inflammation, Not Bacteria Should be Targeted bit.ly/4akb9UH #CDiff #ClostridioidesDifficile
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The role of gut fungi in #Clostridioides difficile infection sciencedirect.com/science/ar… #OpenAccess #mycology #Cdiff
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🏥 Chlorine-based bleach may not kill #Cdiff despite its role as a primary disinfectant, Tina Joshi, MD, of the @PlymUni, told Healio. Based on a study, NaOCl may not kill all spores on surfaces and fabric, leading to #HAIs. Click 👇 for more bit.ly/3SWK0kw
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.@CrestonePharma is currently enrolling patients for the 19-0021 Phase 2 clinical study, a randomized, double-blind evaluation of its novel antibiotic CRS3123 versus oral vancomycin to treat adults with #CDiff infection (CDI). For more info, visit: bit.ly/3XQZ1Us
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@ellermeierlab reports a new TCS mediating resistance to daptomycin & bacitracin in Cdiff. journals.asm.org/doi/10.1128… Check our the Commentary by @ErinBPurcell journals.asm.org/doi/10.1128… @ASMicrobiology @JBacteriology
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Recent trends and risk factors associated w/ #Cdiff infections in hospitalized patients with #IBD 🔖Alimentary Pharmacology and Therapeutics 👥E Spartz @drdedeck @KushFansiwalaMD @ShayaNoorian A Roney @Hakimian_MD J Sauk @pohungVChen @berkeleydoc 👉onlinelibrary.wiley.com/doi/…
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