Plant development, small RNAs, plant-pathogen interactions, and Phytophthora. @ SJTU
Shanghai
Joined November 2015
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Great congrats to @wenboEffector! Super exciting to be a member of this growing sRNA-Defense research field. Expect more wonderful news from Ma lab 😊
We are thrilled to announce that @wenboEffector has been awarded a highly competitive @ERC_Research Advanced Grant for her new project sRNA-Defense, which will allow her and her team to uncover new roles for sRNAs in defending plants from pathogens 🧬🌱
tsl.ac.uk/news/srna-revoluti…
ALT Photo of Prof Wenbo Ma FRS to announce her ERC Advanced Grant. TSL and ERC logos are included.
Whether apoplastic small RNAs regulate plant immunity? Check our work in tomato identified their roles in priming plant defence to Phytophthora. Thanks for the wonderful suggestion from @wenboEffector and the professional processing of the editors at MP
An Extracellular miRNA Reshapes Cell Wall Integrity to Prime Systemic Immunity in Tomato #Research #MolecularPlant cell.com/molecular-plant/ful…
Yingnan Hou retweeted
Super excited to preprint this work and extremely proud of my team @TheSainsburyLab. Many thanks to fantastic collaborators @XiaoqiFeng_m @Tolga_Bzkrt and @Cerhou
This work is spearheaded by the amazing postdoc Min Wang @Min_Wang6
Below is a thread 👇👇👇
New Preprint: A specialized ARGONAUTE enables trans-species RNA interference in plant immunity (2026)
tsl.ac.uk/publications/16450…
Yingnan Hou retweeted
Rising Stars in Plant Sciences 2026 (RSPS2026) Award | Call for Applications | Deadline: March 31, 2026 | Detailed information about this event can be found at cell.com/cemps/rsps-awards
Yingnan Hou retweeted
TIR domain-containing proteins employ dual regulatory mechanisms to confer TaEDS1-dependent immunity in wheat #research #MolecularPlant cell.com/molecular-plant/ful…
Our collaborated research identified a two-layer epigenetic mechanism to silence Avr genes in Phytophthora sojae and enable host adaptation in soybean. Please check academic.oup.com/nar/article…
Yingnan Hou retweeted
Excited to preprint work mainly by former postdocs Li Feng, Yingnan Hou @Cerhou, and the phylogenomics genius @amiralito_ @TheSainsburyLab. We found a plant defense gene family enabling pathogen gene silencing & explored engineering this pathway to boost disease resistance!
A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity biorxiv.org/content/10.1101/… #biorxiv_plants
A brief summary about the dual role of plant metabolites in plant-microbe interactions and pathogen adaptive strategy
Candy or poison: Plant metabolites as swing factors against microbes #spotlight #MolecularPlant cell.com/molecular-plant/abs…
Great congrats to @wenboEffector and @Hui84282116 ! Super exciting to be involved in this inspiring research！Expect more wonderful news from Ma lab 😊
Super excited to see this paper out! Many thanks to wonderful colleagues @TheSainsburyLab and collaborators @Frank_Menke @danmaclean Yanli Wang (CAS)
open access article sciencedirect.com/science/ar…
Hui's @Hui84282116 excellent🧵 with the preprint
xitter.cf/Hui84282116/status/165…
A fantastic story from Ma lab, showing the functional diversity and conservation of oomycete effectors. Congratulations!
Pathogens are notorious for producing diverse effector proteins that manipulate host cellular processes. But how is functional diversity generated in an effector repertoire? Thrilled to share our fascinating story. biorxiv.org/cgi/content/shor…… #biorxiv_plants
We talked about the "small" players in plant immunity with robust function, and discussed their "shotgun" model in defeating parasites. For more details, pls check our paper @MPPjournal and highlight @BS_PP
What is RNA interference and why is it important for plant immunity?
@Cerhou 's team have investigated small interfering RNAs or "siRNAs" and their role in plant defence
Read more in a new @MPPjournal highlight #blog
ow.ly/OwXf50K9io4 @wileyplantsci
#siRNA #plantdefence
ALT Graphic representing a host plant cell (green box on a white background) defending against viruses, bacteria, filamentous pathogens (e.g. fungi and oomycetes) and parasitic plants using siRNAs. Each organism is shown as a labelled graphic outside of the host, except virus. siRNAs inside the box connect to the organisms with straight lines & flathead arrows. "siRNA sorting mechanisms" is written over the box boundary
Yingnan Hou retweeted
Plant extracellular RNA-protein complexes are located outside the EVs! #sRNA #circularRNA #extracellularvesicles
Arabidopsis apoplastic fluid contains sRNA- and circular RNA-protein complexes that are located outside extracellular vesicles @rogerinnes1 @HZK_Biology @PatBaldrich #PlantSci buff.ly/3oPrzOD
Incredible progress in gene editing pursuing the balance between enhanced resilience and high yield! Congratulations!
I'm thrilled to share our 8-year effort @Nature describing disease resistant wheat without yield penalties! We use multiplex genome editing to create a 304-kilobase pair deletion, which revealed a novel relationship between disease resistance and growth.
nature.com/articles/s41586-0…
Yingnan Hou retweeted
InterView with Dr. Wenbo Ma - Interactions shar.es/aW00sG #inspiring #WomenInScience #mpmi @wenboEffector @TheSainsburyLab @ISMPMI
Big congratulations @wenboEffector
We are thrilled that our senior group leader, Prof Wenbo Ma, received the Ruth Allen Award from the American Phytopathological Society for her outstanding contributions to plant pathology research.
apsnet.org/members/give-awar…
ALT A photo of Prof Wenbo Ma, Senior Group Leader, in the laboratory. Prof Nick Talbot FRS, Executive Director of The Sainsbury Laboratory, says "It is fantastic to see Wenbo's innovative research on effector biology, small RNAs in plant immunity, and so many contributions to plant-microbe interactions recognized in this way"
Yingnan Hou retweeted
It’s finally out! Plant cells are so smart to use these signaling molecules precisely~ BSL phosphatases jointly regulate both BIN2 and YDA to enable stomata asymmetric cell division. 🌱
New Article: "A spatiotemporal molecular switch governs plant asymmetric cell division"
rdcu.be/cjTR8
BASL is a crucial regulator of stomatal development. BSL phosphatases are BASL binding partners and reveal the molecular mechanism of cell-fate asymmetry in stomata.
Thanks for the invitation to share my experience in a tough transition that made me a better version of myself.
Starting a research lab is tough. But, what if you had to start a lab during a pandemic?
⬇️Here, we check in with 6 new faculty members who share their experiences , from the early stages of confusion and anxiety, to also the recovery and rebuilding.
cell.com/iscience/fulltext/S…
ALT A card depicting the headshots of six scientists who just started there research group in the last year. iScience and Cell Press branding around text: "Interdisciplinary Backstory"
Yingnan Hou retweeted
bioRxiv: The host exocyst complex is targeted by a conserved bacterial type III effector protein that promotes virulence (2020) | @scoopit sco.lt/4vSQDI
Yingnan Hou retweeted
Professor Wenbo Ma * How the molecular interactions between plants and microbes lead to either immunity or disease * Plant health discovery for a sustainable future
Watch @wenboEffector say more about her research & why she joined our research institute. tsl.ac.uk/?p=10039