@CichowskiLab

Karen Cichowski Lab @BrighamWomens. We study how deregulated cell signaling drives cancer, particularly #RAS-driven tumors. Posts by lab members.

 Boston, MA
Joined September 2021
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Newest work from our group led by Amy Schade shows that EZH2 and AKT inhibitors combine to induce shrinkage of TNBC tumors by hijacking mechanisms of involution, now published in @Nature nature.com/articles/s41586-0…

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

Nature - AKT inhibitors synergize with agents that suppress the histone methyltransferase EZH2 and promote robust tumour regression in multiple triple-negative breast cancer models in vivo by...

nature.com
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