
Posting from Colin Nichols' electrophysiology lab at @WUSTL. Focused on ion channels biophysics & role in physiology and pathology.
Saint Louis, Missouri
Joined March 2023
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Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Mitochondrial Ca2+-coupled generation of reactive oxygen species, peroxynitrite formation, and endothelial dysfunction in Cantú syndrome
@vesselman @ColinNicholsLab @JCI_insight insight.jci.org/articles/vie…
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Congratulations to Drs. Irfan Lodhi, Jeffrey Millman, Maria Remedi, and Julie Silverstein on achieving full professorship in their careers! Learn about each of their journeys: bit.ly/3Xs4FyM. @JeffreyRMillman @LodhiLab @WUDeptMedicine
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
And that’s a wrap! From all of us at @physoc & @scandPhys, thanks for joining us in Newcastle. It’s been a fantastic 3 days of inspiring science & unmissable networking. @NorthumbriaUni have been fantastic hosts. Safe journeys home! #PhysiologyinFocus2024
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
The annual Cantu clinic and symposium took place from 6/19/24 to 6/21/24. Natural history was collected for new and returning patients while collaborating with WashU research, the medical team, and patient advocacy. continuing to build a very special community.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Pleased to share our latest work in final form!
Modulation of TMEM16B channel activity by the calcium-activated chloride channel regulator 4 (CLCA4) in human cells - JBC jbc.org/article/S0021-9258%2…
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Our latest publication identifying the CLCA family as potentiators of the TMEM16 Cl Channel family:
Modulation of TMEM16B Channel Activity by the Calcium-Activated Chloride Channel Regulator 4 (CLCA4) in Human Cells - Journal of Biological Chemistry jbc.org/article/S0021-9258%2…
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Fantastic dinner with @ColinNicholsLab @ChandaLab06 Maria Remedi to celebrate a fantastic talk by Nancy Carrasco @VanderbiltMPB for CIMED research day. An amazing scientific story spanning basic research to public health! @WUSTLPCCM @BBSBwustl
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Ecstatic to report the NOA for our new Co-PI R01 with @JABLab3 ! So excited to embark on this pioneering collaborative work in Cystic Fibrosis! Thanks to collaborators @ColinNicholsLab & Mark Miller! @WUSTLmed @WUSTLPCCM @BBSBwustl @WashUDPS
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Congrats to Sumit Patel in the Remedi lab at Washington University for his new publication in Metabolism "Intermittent fasting protects β-cell identity and function in a type-2 diabetes"
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
The Rare Disease Day Symposium hosted by WashU on Leap Day had a phenomenal mix of Keynote speakers, posters, short abstract oral presentations, and well attended Patient and Family Meet and Greet.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Don't forget to wear stripes on 2/29/2024 in support of those affected by rare diseases.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
We are one month away! The zebra is the symbol adopted for Rare Disease Day as noted for its unique black and white stripes. Will you show your stripes on 2/29/2024?
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Please join us tomorrow morning for Cardiology #GrandRounds with Dr. Colin Nichols @ColinNicholsLab !
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
So much more than a competition 📸
We caught up with some of our past entrants to discuss their stories, their hopes for the future and what being part of the EURORDIS Photo Award means to them!
📰 go.eurordis.org/7QLYnW

ALT Collage of three photos. The first depicts two young girls in wheelchairs smiling, laughing ad holding hands. In the second, a young girl lies on her front with her chin in her hands smiling down at the camera. The third shows a girl in a wheelchair being carried up a mountain as part of a trekking group.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
We are accepting abstracts until noon on 12/8/2024 @ rarediseasesday.wustl.edu/. Click on proposals and submit your abstract ASAP.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Exciting days at the MCB/CBP retreat! Outstanding presentations and stimulating discussions highlighting cutting-edge research from various labs. A big cheer for our new graduate students whose enthusiasm and inquisitive spirits are truly energising @WUSTLCellBio @WUSTLdbbs
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Congratulations to Sumit Patel on receiving the Best Poster Award at the Midwest Islet Conference earlier this year: bit.ly/3Sg5ad1.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Impressive work by Dr. Maria Remedi and colleagues on the critical importance of understanding insulin secretion disruption associated with KATP loss: bit.ly/46SvaPN.
Colin Nichols Lab @colinnicholslab.bsky.social retweeted
Maksaev et al. @ColinNicholsLab report the discovery of voltage-dependent inhibition of TRPV #ionchannels by intracellular polyamines and develop a kinetic model of this process bit.ly/3yA3v6V
In our collection on the Physiology of Pain bit.ly/48mq9R7
#SGP2023

























