Researcher in neuroimaging and brain connectivity @EdinUniLBC
Edinburgh, Scotland
Joined December 2015
- Tweets124
- Following871
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New preprint: In ~38k people, general cognitive function ('g') is supported by a widely distributed white matter network, spanning all cortical lobes + key subcortical structures, with long-range inter-lobar connections playing a key role. Effects strengthen with age.
ALT Edge-level associations between g and white matter connections.
Colin Buchanan retweeted
Living in deprived areas is associated with structural differences in the brains of older people, as our study has shown using the @EdinUniLBC
🆕 publication in @molpsychiatry
🧠🧠🧠🧠🧠🧠
nature.com/articles/s41380-0…
🧵
Colin Buchanan retweeted
Wave 7 of #LBC1936 began on 21 March:
Ten participants have come back for #cognitive appointments so far and the first #participant joined the radiographers @EdinUniImaging for an MRI scan on 18 April!
@EdinburghUni
@SchoolofPPLS
@EdinUniNeuro
@age_uk
@agescotland
Colin Buchanan retweeted
The latest issue of the Disconnected Mind Newsletter is now out on our website: edin.ac/4aW2Y0Z
@EdinburghUni
@SchoolofPPLS
@EdinUniNeuro
@agescotland
@age_uk
Colin Buchanan retweeted
Had an AMAZING time at the Doors Open Day!
Thanks to all who dropped by & participated in the activities🥳
We loved reading your feedback! 😇
Huge thanks to @EdinUniLBC @lyons_lab @ColinRBuchanan & others who made #EdinburghOpenDay possible😊
#neuroscience #scicomm #science
ALT Researchers looking into microscopes kept at a table
ALT 4 people standing behind a long table with multiple objects kept on it
ALT People wearing Augmented Reality glasses looking at something
ALT Exhibitor talking to a visitor with objects kept on the table
Colin Buchanan retweeted
Mapping connectomes with tractography?
Check out this thread on our work evaluating tractogram filters: SIFT, LiFE, COMMIT
Filters improve connectome accuracy, but improvement is modest for complex fiber architectures
Tabinda Sarwar @ADaducci @simonaschiavi24 @Lestropie
1/5 Working with whole brain tractograms is challenging. Don't miss this new paper to learn more about why 👉 sciencedirect.com/science/ar… Another difficult thing is to compare different #tractography algorithms 👇
Colin Buchanan retweeted
Lessons from Complex Trait Genetics may help us overcome the Neuroimaging replication crisis
doi.org/10.1016/j.cortex.202…
My Viewpoint identifies striking parallels between the fields of Complex Trait Genetics and Neuroimaging research 🧵🧠🧬
ALT Population genetics (AFurtjes)
Colin Buchanan retweeted
I have a new preprint! psyarxiv.com/62txs
If a brain structure is associated with a cognitive task, how much of this is related to a specific cognitive domain, and how much of this is complicated by the existence of 'general intelligence' or g?🧐
Colin Buchanan retweeted
In the next session, Anna Fürtjes (@Anna_Furtjes) provides systematic and quantitative evidence on the extent to which atlas choice affects findings and likely contributes to to lack of reproducibility in atlas-based research. Poster 2411
Colin Buchanan retweeted
Colin Buchanan (@siliconsoup) presents the largest-ever meta-analysis of nearly 10,000 healthy adult brains to robustly map the relationship between structural brain connectomes and general cognitive function.
Colin Buchanan retweeted
Jo Moodie (@JoannMoodie) has been looking at spatial correlations between fundamental profiles of cortical organisation (incl gene expression components and neurotransmitter receptor densities) and regions of the cortex associated with general cognitive functioning. Poster 54.
Ever wondered what distinct information is really provided by different graph-theory metrics in the brain's structural connectome?
doi.org/10.1016/j.neuroimage…
Colin Buchanan retweeted
We are celebrating the successful completion of Wave 6 with the #LBC #participants and collaborators this Saturday!
Lothian Birth Cohorts #reunion
@NtlMuseumsScot
@EdinUniNeuro
@EdinUniImaging
@UoE_Psychology
@EdinburghUni
@SchoolofPPLS
@age_uk
@SimonRCox
@DaniellePageUoE
Colin Buchanan retweeted
🆕preprint: living in disadvantaged areas during later life is associated with smaller total #brain and grey matter volume, thinner cortex and white matter disconnectivity among @EdinUniLBC participants. @CRESHnews @SimonRCox @jamie0pearce @siliconsoup
medrxiv.org/content/10.1101/…
Colin Buchanan retweeted
We absolutely loved the coverage of the LBC studies on #WhoLivesInScotland last night. What a great show and with so many interesting stats, great stories and positive messages!
If you missed it, it's well worth catching up here!
edin.ac/3NbYvvW
Colin Buchanan retweeted
LBC1936 study in the Guardian!
Read about Dr Judy Okely’s study now published in Psychological Science on the benefits of playing a musical instrument in childhood for cognitive ageing:
theguardian.com/education/20…
@JudyOkely @SchoolofPPLS @ESRC @age_uk @EdinUniCAHSSres
Colin Buchanan retweeted
The LBC is contributing to a new #BBC #documentary series called 'Who Lives in #Scotland'.
Filming today at Wellcome Trust Clinical Research Facility @EdinburghCRF
Presenter Martin Geissler talks about the study with Ian Deary, Judy Okely and #LBC1936 participants
Colin Buchanan retweeted
Some of the LBC1921s have #brain imaging data at age ~92 years, which is very rare, especially with their #cognitive data at age 11.
Here's a paper which brought both LBC cohorts together to look at brain and cognitive #ageing:
edin.ac/3mt7i04
@EdinUniImaging
Colin Buchanan retweeted
"Median connectivity is estimated as ~6200 axons between cortical areas within-hemisphere"
Human cortical areas are sparsely connected: Combining histology with diffusion MRI to estimate the absolute number of axons | #bioRxiv biorxiv.org/content/10.1101/…
