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CooperGroup

@CooperMassSpec

Our research focuses on the development of novel methods for in situ analysis of biomolecules by mass spectrometry. https://teapawt.org/t.co/BeWNPVSZpQ

 Birmingham, United Kingdom.
biosciences-labs.bham.ac.uk/cooper/
Joined March 2013
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  • Following71
  • Followers426
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Congratulations to Oli on his paper published today in JASMS! Infrared Photoactivation Enables nano-DESI MS of Protein Complexes in Tissue on a Linear Ion Trap Mass Spectrometer | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas…

Infrared Photoactivation Enables nano-DESI MS of Protein Complexes in Tissue on a Linear Ion Trap...

Abstract. Native mass spectrometry analysis of proteins directly from tissues can be performed by using nanospray-desorption electrospray ionization (nano-

pubs.acs.org
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Congratulations to Oli on his paper published today in Nature Communications! nature.com/articles/s41467-0…
Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates...

Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates...

Nature Communications - In this work, protein-metal complexes implicated in the pathogenesis of amyotrophic lateral sclerosis were mapped by mass spectrometry imaging. Metal-deficient hSOD1G93A...

nature.com
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Looking forward to #ASMS2024 and presenting our latest work analysing proteoforms directly from tissue. Helen will also present in Thermo’s breakfast seminar, Wednesday morning.
Presentations: TOG am 08:50, TOA am 10:10 and ThP 755

ALT Presentations: TOG am 08:50, TOA am 10:10 and ThP 755

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Congratulations to James, Emma and Oli on their paper in Chemical Science: Chemical Science, 2024, DOI: 10.1039/D3SC04933G @ChemicalScience #MyFirstChemSci
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Come and join the Cooper group! We are recruiting for PhD studentships. Details below: 1) Midlands Integrative Biosciences Training Partnership: findaphd.com/phds/project/ne… More details at: warwick.ac.uk/fac/cross_fac/… 2) Midlands Mental Health & Neuroscience DTP midlandsmhndtp.ac.uk/project…
New tools for structural biology: Native ambient mass spectrometry at University of Birmingham on...

New tools for structural biology: Native ambient mass spectrometry at University of Birmingham on...

PhD Project - New tools for structural biology: Native ambient mass spectrometry at University of Birmingham, listed on FindAPhD.com

findaphd.com
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Come and join us in Birmingham in November for BMS SIG! Great line-up of speakers and training/workshops. Abstract deadline 16th October!
British Mass Spectrometry Society (@bmss_official) profile pictureBritish Mass Spectrometry Society@bmss_official9 Oct 2023
Time is ticking! ⏰ The deadline for abstract submissions and registration for the British Mass Spectrometry Society - BMSS Biomacromolecular Structure SIG Meeting 2023 is approaching fast! Don't miss out ...submit here: bmss.org.uk/bmss-biomacromol…
Image from British Mass Spectrometry Society (@bmss_official)
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Congratulations to Emma on her paper in JACS! Tissue Washing Improves Native Ambient Mass Spectrometry Detection of Membrane Proteins Directly from Tissue | Journal of the American Chemical Society pubs.acs.org/doi/full/10.102…
Tissue Washing Improves Native Ambient Mass Spectrometry Detection of Membrane Proteins Directly...

Tissue Washing Improves Native Ambient Mass Spectrometry Detection of Membrane Proteins Directly...

abstract. Native ambient mass spectrometry enables the in situ analysis of proteins and their complexes directly from tissue, providing both structural and

pubs.acs.org
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Excited to see this preprint out with Oli Hale and @CooperMassSpec on using UniDec for Imaging Mass Spec. Using the new workflow, you can deconvolve imaging data sets to produce mass images of proteins and proteoforms! go.shr.lc/3NqOUCZ
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Catch members of the Cooper group at #ASMS2023 next week to discuss mass spectrometry imaging of protein complexes, membrane proteins and in-situ proteomics!
Image from CooperGroup (@CooperMassSpec)
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Congratulations to Jana Havlikova on graduating!
Image from CooperGroup (@CooperMassSpec)
Image from CooperGroup (@CooperMassSpec)
Image from CooperGroup (@CooperMassSpec)
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Congratulations to Kish on winning the Barber prize at #BMSS42!
Kish Adoni (@AdoniKish) profile pictureKish Adoni@AdoniKish14 Sep 2022
Very pleased to present my work on novel S-Glutathionylation of the Cyanobacterial Phycobilisome at BMSS42. Thanks to all who attended, and watch this space on the progress of this project! 🦠🧑🏾‍🔬@Leney_MassSpec
Image from Kish Adoni (@AdoniKish)
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The Cooper group and @Leney_MassSpec group get the TIMS experience courtesy of @BrukerMassSpec #IMSC2022
A group of mass spectrometrists get a taste of their own medicine

ALT A group of mass spectrometrists get a taste of their own medicine

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Helen Cooper presents native ambient mass spectrometry at #IMSC2022 Membrane protein complexes and protein-drug complexes analysed directly from bulk tissue!
Image from CooperGroup (@CooperMassSpec)
Image from CooperGroup (@CooperMassSpec)
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Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex in Tissue from Orally Dosed Rats onlinelibrary.wiley.com/doi/…
Inside Back Cover: Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex...

Inside Back Cover: Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex...

Flying elephants and delicate cargo. Electrospray ionization of proteins has been likened to making molecular elephants fly. In their Communication (e202202075), Helen J. Cooper and co-workers...

onlinelibrary.wiley.com
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Congratulations to Eva, Oli, James and team on their paper in Angewandte Chemie! Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex in Tissue from Orally Dosed Rats onlinelibrary.wiley.com/doi/…
Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex in Tissue from...

Mass Spectrometry Detection and Imaging of a Non‐Covalent Protein–Drug Complex in Tissue from...

The intact protein–drug complex formed in vivo between endogenous liver fatty acid binding protein (FABP1) and the small molecule therapeutic bezafibrate was detected in ex vivo liver tissue from...

onlinelibrary.wiley.com
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Delighted that our publication in Angew. Chem. Int. Ed. has been designated a "Hot Paper"! Native Ambient Mass Spectrometry of an Intact Membrane Protein Assembly and Soluble Protein Assemblies Directly from Lens Tissue onlinelibrary.wiley.com/doi/…

Native Ambient Mass Spectrometry of an Intact Membrane Protein Assembly and Soluble Protein...

The integral membrane protein assembly Aquaporin-0 was analysed by native ambient mass spectrometry of eye lens tissue. Membrane protein assemblies were solubilised by detergent micelles. Spatially...

onlinelibrary.wiley.com
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New from Helen Cooper and first author Yuying Du from @CooperMassSpec: 'Native ambient mass spectrometry of intact protein assemblies directly from Escherichia coli colonies' 🔓 From our collection celebrating 10 years of Emerging Investigator issues. rsc.li/3aTQKf5
Native ambient mass spectrometry of intact protein assemblies directly from Escherichia coli...

Native ambient mass spectrometry of intact protein assemblies directly from Escherichia coli...

Here, we demonstrate that by combining electroporation with native ambient mass spectrometry, it is possible to detect intact non-covalent protein complexe

pubs.rsc.org
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Congratulations to Eva and team on their paper in JASMS! Quantitative Characterization of Three Carbonic Anhydrase Inhibitors by LESA Mass Spectrometry pubs.acs.org/doi/10.1021/jas…
Quantitative Characterization of Three Carbonic Anhydrase Inhibitors by LESA Mass Spectrometry

Quantitative Characterization of Three Carbonic Anhydrase Inhibitors by LESA Mass Spectrometry

Abstract. Liquid extraction surface analysis (LESA) coupled to native mass spectrometry (MS) presents unique analytical opportunities due to its sensitivit

pubs.acs.org
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Congratulations to Helen on winning the @RoySocChem 2022 Theophilus Redwood Award! #RSCPrizes Professor Helen Cooper - 2022 Analytical Division open Award: Theophilus Redwood Award winner rsc.org/prizes-funding/prize… via @RoySocChem
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Congratulations to Oli on his paper in Angewandte Chemie! Native Ambient Mass Spectrometry of an Intact Membrane Protein Assembly and Soluble Protein Assemblies Directly from Lens Tissue onlinelibrary.wiley.com/doi/…
Native Ambient Mass Spectrometry of an Intact Membrane Protein Assembly and Soluble Protein...

Native Ambient Mass Spectrometry of an Intact Membrane Protein Assembly and Soluble Protein...

The integral membrane protein assembly Aquaporin-0 was analysed by native ambient mass spectrometry of eye lens tissue. Membrane protein assemblies were solubilised by detergent micelles. Spatially...

onlinelibrary.wiley.com
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