@Crit_Care

Critical Care is an international open access journal that publishes articles in all areas of intensive care and emergency medicine.

 London, UK
ccforum.biomedcentral.com/
Joined July 2013
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馃尙锔廚ew in #CriticalCare: A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study doi.org/rt8q #CritCare #Weaning #PRiVENT

A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patien...

Critical Care - Effective strategies to prevent weaning failure and prolonged invasive mechanical ventilation (IMV) in patients at high risk of weaning failure are limited. We evaluated a...

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馃New in #CriticalCare: Comparison of two automated pupillometry indices in patients with acute brain injury: the prospective multicentre LYNX cohort study doi.org/rs59 #CritCare #BrainInjury #LYNXcohort

Comparison of two automated pupillometry indices in patients with acute brain injury: the prospec...

Critical Care - Automated pupillometry quantifies the pupillary light reflex in acute brain injury. The neurological pupil index (NPi) is the established composite index and carries prognostic...

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馃彞New in #CriticalCare: Increased ureagenesis revealing metabolic intolerance to enhanced nutrition in the PICU: a secondary analysis of the PEPaNIC RCT doi.org/rs58 #CritCare #PICU #Ureagenesis

Increased ureagenesis revealing metabolic intolerance to enhanced nutrition in the PICU: a second...

Critical Care - As compared with withholding parenteral nutrition (PN) for one week (late-PN), early supplementation of insufficient enteral nutrition with PN (early-PN) increased infection risk...

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馃New in #SepsisAndSevereInfection: Sepsis in the major burn patient doi.org/rs57 #CritCare #Sepsis #SevereInfection #Burns

Sepsis in the major burn patient

Critical Care: Sepsis and Severe Infection - Sepsis in the context of major burn injury presents a significant challenge to clinicians. It affects a substantial proportion of patients with major...

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馃└New in #CriticalCare: Beyond macrocirculatory targets: a multimodal framework for microcirculatory and organ perfusion monitoring in sepsis doi.org/rscs #CritCare #Macrocirculation #Microcirculation #Sepsis

Beyond macrocirculatory targets: a multimodal framework for microcirculatory and organ perfusion...

Critical Care - Microcirculatory dysfunction may persist despite restoration of conventional macrocirculatory targets in sepsis, reflecting loss of hemodynamic coherence. This review synthesizes...

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馃КNew in #CriticalCare: The NLRP3 inflammasome in physiological and dysfunctional host response in human sepsis and critical illness: a narrative review doi.org/rscr #CritCare #Sepsis #CriticalIllness

The NLRP3 inflammasome in physiological and dysfunctional host response in human sepsis and...

Critical Care - The NLRP3 inflammasome is a cytosolic multiprotein complex that serves as a key regulator of innate immunity by reacting to pathogen- and damage-associated signals and orchestrating...

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馃枼锔廚ew in #SepsisAndSevereInfection: Global trends and hotspots of the sepsis machine learning prediction model: a bibliometric analysis doi.org/rrqw #CritCare #Sepsis #SevereInfection #MachineLearning

Global trends and hotspots of the sepsis machine learning prediction model: a bibliometric analysis

Critical Care: Sepsis and Severe Infection - Sepsis is a systemic syndrome caused by infection-induced organ dysfunction, and machine learning prediction models have shown important value in the...

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馃└New in #CriticalCare: Personalised energy targeting during venovenous ECMO: serial assessment of resting energy expenditure reveals phase-dependent metabolic demand and systematic discordance with predictive equations doi.org/rrq2 #CritCare #ECMO #EnergyTargeting

Personalised energy targeting during venovenous ECMO: serial assessment of resting energy expendi...

Critical Care - In patients receiving extracorporeal membrane oxygenation (ECMO), metabolic demand varies dynamically across the disease course, while conventional indirect calorimetry in ECMO...

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馃New in #CriticalCare: Nurse-led respiratory care bundle and pneumonia prevention in critically ill patients with abdominal sepsis: a multicenter before-and-after controlled study doi.org/rrqz #CritCare #Pneumonia #Sepsis

Nurse-led respiratory care bundle and pneumonia prevention in critically ill patients with abdomi...

Critical Care - Patients with abdominal sepsis face an increased risk of pneumonia due to systemic inflammation, prolonged bed rest, impaired cough reflex, and respiratory muscle dysfunction....

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馃珌New in #CriticalCare: Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial) doi.org/rrqx #CritCare #COPD #Ventilation

Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical...

Critical Care - Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) requiring invasive mechanical ventilation (IMV) are associated with high mortality and long-term disability....

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馃└New in #CriticalCare: Physiological limits of capillary refill time: a human endotoxemia study doi.org/hcjtz2 #CritCare #Capillary #Endotoxemia

Physiological limits of capillary refill time: a human endotoxemia study

Critical Care - The capillary refill test is a widely used bedside marker of tissue perfusion, but its reliability during acute inflammation is not well characterised. The guiding 3-s threshold...

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馃珋New in #CriticalCare: Left ventricular unloading during VA-ECMO for refractory cardiogenic shock: a target trial emulation multicenter analysis doi.org/rqxg #CritCare #ECMO #CardiogenicShock

Left ventricular unloading during VA-ECMO for refractory cardiogenic shock: a target trial emulat...

Critical Care - Conflicting data exist regarding the survival benefit of mechanical left ventricular (LV) unloading in patients receiving peripheral venoarterial extracorporeal membrane oxygenation...

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馃New in #SepsisAndSevereInfection: Unraveling the mitochondrial鈥搇ysosomal crosstalk: a new frontier in sepsis-induced acute lung injury doi.org/rqxf #CritCare #Sepsis #SevereInfection #Mitochondria #Lysosome

Unraveling the mitochondrial鈥搇ysosomal crosstalk: a new frontier in sepsis-induced acute lung injury

Critical Care: Sepsis and Severe Infection - Sepsis-induced acute lung injury (S-ALI) and sepsis-associated acute respiratory distress syndrome (ARDS) remain major contributors to respiratory...

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馃珋New in #CriticalCare: AKI as a systemic syndrome and its impact on other organ systems doi.org/rpwb #CritCare #AKI #OrganSystems

AKI as a systemic syndrome and its impact on other organ systems

Critical Care - Acute kidney injury (AKI) affects approximately 15% of all hospitalized individuals and nearly half of those admitted to intensive care units and is increasingly recognized as a...

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馃尙锔廚ew in #CriticalCare: Physiological comparison of high-flow oxygen via endotracheal tube and T-piece strategies during spontaneous breathing trials: a randomized crossover study doi.org/rpv9 #CritCare #Oxygen #RandomizedCrossover

Physiological comparison of high-flow oxygen via endotracheal tube and T-piece strategies during...

Critical Care - The optimal spontaneous breathing trial (SBT) strategy remains uncertain because commonly used approaches involve distinct physiological trade-offs. Pressure support ventilation...

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馃拪New in #CriticalCare: Beta-lactam antibiotics have immunomodulatory effects in vitro, including changes consistent with sepsis-induced immunosuppression doi.org/rpv8 #CritCare #Antibiotics #Immunosuppression

Beta-lactam antibiotics have immunomodulatory effects in vitro, including changes consistent with...

Critical Care - Sepsis is associated with immunosuppression, predisposing patients to secondary infections. Many treatments routinely used for infections have immunomodulatory effects, including...

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馃應New in #CriticalCare: Conflict in intensive care units: a conceptual framework for patient, family, team, and inter-service disagreement doi.org/rn2w #CritCare #ICU #Conflict

Conflict in intensive care units: a conceptual framework for patient, family, team, and inter-ser...

Critical Care - For clinicians, conflict in the intensive care unit (ICU) is both common and expected owing to the nature of critical illness and its treatment. Examination of conflict in this...

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馃ゼNew in #SepsisAndSevereInfection: Overlap-weighted retrospective cohort study of early versus delayed renal replacement therapy in sepsis-associated AKI doi.org/rn2v #CritCare #Sepsis #SevereInfection #RRT

Overlap-weighted retrospective cohort study of early versus delayed renal replacement therapy in...

Critical Care: Sepsis and Severe Infection - The optimal timing of continuous renal replacement therapy (CRRT) initiation in sepsis-associated acute kidney injury (SA-AKI) remains controversial....

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馃New in #CriticalCare: The evolution of biocontainment unit care for high-consequence infectious diseases: progress, lessons learned, and future directions doi.org/rm89 #CritCare #Biocontainment #InfectiousDisease

The evolution of biocontainment unit care for high-consequence infectious diseases: progress,...

Critical Care - Biocontainment units (BCUs) are specialized facilities designed to treat patients with high-consequence infectious diseases (HCIDs) which are pathogens with high mortality rates,...

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馃彞New in #CriticalCare: Patient-level reclassification and discordance between SOFA and SOFA-2: a multicenter ICU study doi.org/rm88 #CritCare #SOFA #ICU

Patient-level reclassification and discordance between SOFA and SOFA-2: a multicenter ICU study

Critical Care - The Sequential Organ Failure Assessment (SOFA) score is widely used to quantify organ dysfunction in critically ill patients. A revised version, SOFA-2, was proposed to better...

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