@DPicketts

Epigeneticist studying neurodevelopment and intellectual disability. Senior scientist at the OHRI and Professor @uOttawaMed.Tweets my own.

Joined August 2014
  • Tweets418
  • Following388
  • Followers301
41Media
Excited to share our paper with Ghayda Mirzaa describing the novel SMARCA1-related NDD. Out today in Nature Communications. rdcu.be/ePaDp
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David Picketts retweeted
Lynn Megeney@MegeneyLab25 Sep 2024
Our commentary on a recent publication in Cell Reports highlighting a very exciting set of observations Destruction as a creative process: CAD-induced DNA strand breaks promote macrophage differentiation: Cell Reports cell.com/cell-reports/fullte…

Destruction as a creative process: CAD-induced DNA strand breaks promote macrophage differentiation

In a recent issue of Cell Reports, Maurya et al. demonstrated that Drep4, the Drosophila homolog of caspase-activated DNase (CAD), drives DNA strand breaks during myeloid-like/macrophage cell...

cell.com
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🎉 Huge congratulations to Dr. Katey Rayner of @uOttawaMed on being appointed as chief scientific and vice-president of #Research at @HeartInstitute! 👏
Heart Institute@HeartInstitute10 Apr 2024
Following a rigorous international recruitment process, the University of Ottawa Heart Institute has named Dr. Katey Rayner as its next chief scientific officer and vice-president of research. Congratulations! ow.ly/vue050Rcg9g @KateyRayner #ottnews
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The Ottawa Hospital is delighted to announce the appointment of Dr. Rebecca Auer as Executive Vice-President of Research and Innovation at The Ottawa Hospital and CEO and Scientific Director of the hospital’s research institute. ohri.ca/newsroom/story/view/…
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Maxime Rousseaux@maximewc28 Mar 2024
Happy to share the latest from the lab. A fun collaboration with @Russell_BioLab looking at stress-specific regulators of #autophagy using tandem pooled kinome screens. Feedback most welcome. biorxiv.org/content/10.1101/…

Identification of stress specific autophagy regulators from tandem CRISPR screens

Autophagy is a conserved degradative process that promotes cellular homeostasis under stress conditions. Under nutrient starvation autophagy is largely non-selective, promoting the indiscriminate...

biorxiv.org
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Pleased to share our new paper out @emboreports on the role of Ephrin receptors (EphR) as direct transcriptional targets of PHF6 in regulation of NSCs and impairment of this pathway in the rare intellectual disability syndrome, BFLS. Great teamwork (1) embopress.org/doi/full/10.10…

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual...

EMBO Reports - The plant homeodomain zinc-finger protein, PHF6, is a transcriptional regulator, and PHF6 germline mutations cause the X-linked intellectual disability (XLID)...

link.springer.com
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Great story by Pierre Mattar and his group! Happy to be involved.
This Post is from an account that no longer exists. Learn more
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Congrats Dilan! It’s a great story!!
Arezu Jahani-Asl@JahaniArezu25 Jan 2024
Congratulations @dilanras1 on the official acceptance of your beautiful paper! Well deserved! 🎉👏
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We’ve aged since our first discussions but the passion for science still burns strong!
Lynn Megeney@MegeneyLab24 Dec 2023
Three scientists discussing science🤓😊
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David Picketts retweeted
Blair K. Gage@blairkgage5 Dec 2023
I'm excited to announce the start of the Gage Lab in Ottawa at the Ottawa Hospital Research Institute in the Regenerative Medicine Program @OttawaHospital
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“My research aims to understand why the immune system doesn’t work after #surgery and find therapies to boost it.” Dr. Rebecca Auer is receiving our Chrétien Researcher of the Year Award for her research on #cancer surgery and immunotherapies. ohri.ca/newsroom/story/view/… #ottnews
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Congratulations Dawn!
Ian D Graham@IanDGraham118 Nov 2023
Dawn Stacey's induction as a Fellow of the Royal Society of Canada. Congratulations Dawn! @IKTR_Network @uOttawa_SEPH @TOH_CIR
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David Cook@DavidPCook18 Nov 2023
Excited to announce the Cook Lab will be opening at the Ottawa Hospital Research Institute Jan 2024. We'll be focusing on intratumoural heterogeneity and therapy resistance in ovarian cancer Eager to work more with the ovarian cancer research community! cooklab.ca

Cook Lab — Decoding Gynecologic Disease

Cook Lab — Decoding Gynecologic Disease. Single-cell and spatial genomics of ovarian cancer and endometriosis at OHRI / University of Ottawa.

cooklab.ca
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At the OHRI for 25 years…..dream job. Thanks to my mentors @DavidLillicrap & Doug Higgs; to Ron Worton for taking a chance on me; and the friendship & support of my fantastic lab neighbors: @KotharyLab @RobinJParks @MegeneyLab @Pierre_Mattar_ @Bulman_Genetics & Valerie Wallace.
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Most importantly to all the students, PDFs and technicians who make coming to work everyday an exciting and stimulating experience. Without you I would have never done this well!!!
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And a fantastic dinner it was!! Always great to learn more about wine pairings from @SChenlab
S.ChenLab uOttawa@SChenlab4 Oct 2023
Replying to @BassellLab
Topping up with some homemade roasted leg of lamb paired with a 2011 brunello!
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Canadian health research has been chronically underfunded for the past two decades. As a result, the research ecosystem in this country is in serious trouble! Get more facts and find out what you can do at ow.ly/SZO450PNvOo #ResearchInTrouble #cdnpoli #CDNhealth
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David Picketts retweeted
Lynn Megeney@MegeneyLab14 Sep 2023
Our latest review on Caspase/CAD control of DNA strand breaks made the Cover of TiCB!!! Thanks to my co-authors and collaborators Jan Benada, Dalal Alsowaida and Claus Sorensen. And thanks to Lawrence Marvit and Anita Brozkova for the very cool artwork!!!! 🙂
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David Picketts retweeted
Phil Lallier
@plal2 Sep 2023
A Sens Fan, a Habs fan, and a Leafs fan are climbing a mountain & arguing about who loves their team the most. The Habs fan insists that he is the most loyal & he yells "this is for Montreal!” and jumps off the mountain. Not to be out done, the Sens fan next professes his love for his team. He screams "this is for Ottawa!!" & pushes the Leafs fan off the mountain. #GoSensGo – at Fredericton, New Brunswick
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A well deserved break, if I do say so myself.
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