@DTollervey
Joined December 2013
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Happy to share our latest pre-print on RNA polymerase I termination! biorxiv.org/content/10.1101/… #RNAPITermination Fantastic collaboration with @EPetfalski @DTollervey @MarieWinz @EdinburghUni @IBBPAS #Research #RNA

Transcription termination by RNA polymerase I

Transcription elongation is stochastic and driven by a Brownian ratchet mechanism, making it subject to changes in velocity. However, on regions occupied by multiple polymerases, notably the rDNA,...

biorxiv.org
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David Tollervey retweeted
bioRxiv@biorxivpreprint21 Jul 2020
Integrative Vectors for Regulated Expression of SARS-CoV-2 Proteins Implicated in RNA Metabolism biorxiv.org/cgi/content/shor… #bioRxiv
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Stress-induced translation inhibition through rapid displacement of scanning initiation factors biorxiv.org/content/10.1101/…

Stress-induced translation inhibition through rapid displacement of scanning initiation factors

Cellular responses to environmental stress are frequently mediated by RNA-binding proteins (RBPs). Here, we examined global RBP dynamics in Saccharomyces cerevisiae in response to glucose starvation...

biorxiv.org
David Tollervey retweeted
bioRxiv@biorxivpreprint6 Mar 2020
Nascent transcript folding plays a major role in determining RNA polymerase elongation rates biorxiv.org/cgi/content/shor… #bioRxiv
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Substrate Specificity of the TRAMP Nuclear Surveillance Complexes biorxiv.org/content/10.1101/…

Substrate Specificity of the TRAMP Nuclear Surveillance Complexes

During nuclear surveillance in yeast, the RNA exosome functions together with the TRAMP complexes. These include the DEAH-box RNA helicase Mtr4 together with an RNA-binding protein (Air1 or Air2) and...

biorxiv.org
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