Neurosurgeon, neuroscientist, human and dog mom, social media account manager for my dog. @NeurosurgUCSF
San Francisco, CA
Joined October 2019
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🚨 New in Nature Medicine 🚨
Difficulty walking is one of the most disabling symptoms of Parkinson's disease—and one of the hardest to treat.
Today we're excited to share our new study showing that deep brain stimulation (DBS) can be synchronized to each step a person takes.
New publication!!! Fantastic work by @PoojanShuk90434 on brain activities that underlie turning and how meds and DBS work differently on turns! Check it out
🚶🔄 What does the brain do when we turn and what changes in Parkinson’s disease?
Excited to share our work in npj Parkinson’s Disease! @Nature_NPJ
🧠We recorded from the motor cortex and basal ganglia during walking and turning in 5 people with Parkinson’s.
📉 Better turning was associated with reduced beta activity.
💊⚡ Improvements with medication and DBS were linked to distinct neural signatures, pointing toward more personalized stimulation for gait.
Grateful to @DorisWangLab, our collaborators, and especially our research participants!📖
nature.com/articles/s41531-0…
@NeurosurgUCSF
Doris Wang retweeted
🚶🔄 What does the brain do when we turn and what changes in Parkinson’s disease?
Excited to share our work in npj Parkinson’s Disease! @Nature_NPJ
🧠We recorded from the motor cortex and basal ganglia during walking and turning in 5 people with Parkinson’s.
📉 Better turning was associated with reduced beta activity.
💊⚡ Improvements with medication and DBS were linked to distinct neural signatures, pointing toward more personalized stimulation for gait.
Grateful to @DorisWangLab, our collaborators, and especially our research participants!📖
nature.com/articles/s41531-0…
@NeurosurgUCSF
We are hiring! The Wang Lab is looking for a postdoctoral fellow with strong computational neuroscience/neural engineering background who is interested in working on human translational neuroscience projects on closed loop neuromodulation! Pleas email me if interested!
Doris Wang retweeted
Dr. @DorisWangLab (@NeurosurgUCSF ) on focused ultrasound, incisionless treatment reshaping care for tremor and Parkinson's disease.
Register: sfneurological.member365.com…
#SFNS #ParkinsonsDisease #Neurosurgery
#82: Doris Wang – Adaptive DBS, the Rhythm of Walking, and Restoring Human Movement stimulatingbrains.org/?p=414…
Doris Wang retweeted
Thrilled to share our latest work in @NatureNeuro, showing a reproducible brain signature to predict and prevent attention lapses in children before they happen. A work only made possible by @GMI_Canada mentorship and collaborators @SickKidsNews.
nature.com/articles/s41593-0…
Doris Wang retweeted
An automated #intracortical brain-computer interface, used at home with no researcher intervention, provides long-term and accurate restoration of #speech-based #communication and cursor-based computer usage in a person with severe dysarthria due to ALS. #BCI @NS_Card @SergeyStavisky @DrDavidBrandman
nature.com/articles/s41591-0…
Doris Wang retweeted
.@NeurosurgUCSF researchers developed a “smart” brain implant for patients with Parkinson’s that adjusts stimulation in real time, improving gait. "This is an important step toward a new generation of brain therapies," @DorisWangLab tells @nbcbayarea. ucsfh.org/4vcIwTD
Doris Wang retweeted
A randomized crossover study shows that gait-phase synchronized #adaptive deep brain stimulation is feasible, safe, and reduces falls compared to continuous #stimulation in #ParkinsonsDisease. #DBS #PD.
nature.com/articles/s41591-0…
Great work from @DorisWangLab, @UCSFneurosurg, @kennethlouiephd.
Doris Wang retweeted
New in @NatureMedicine, @DorisWangLab shows that distinct left- and right-leg swing biomarkers can drive DBS that changes on a sub-second timescale with each step. A major advance toward movement-driven, precision-timed neuromodulation for #Parkinsons. nature.com/articles/s41591-0…
This study would not have been possible without an incredible multidisciplinary team led by Dr. Ken Louie!
Thank you to everyone, especially our patients, who made this work possible!
We're excited about what comes next as we continue developing therapies that are personalized, adaptive, and responsive to real-world behavior.
Paper:
nature.com/articles/s41591-0…
Doris Wang retweeted
🚶🏽♂️🔄 Turns are one of the biggest challenges for people with Parkinson's disease. But what does brain activity actually do during a turn in the real world? 🧠🏠
📖 Check out our new preprint to find out!
medrxiv.org/content/10.64898…
