Doug Lewandowski retweeted
In the failing heart, short chain fatty acids (SCFA) are more readily oxidized than ketones & represent an unexplored source of energy production. Read more: ow.ly/moXN50EEwPH #AHAJournals @DougLewandowski
News from our lab and the result of great collaborations with the folks at Columbia in NY and the Schulze lab at U. Jena in Germany
Lewandowski's lab show that long-chain acyl coenzyme A is depleted in failing hearts. Restoring it via #ASCL1 activation and mechanical unloading attenuates cardiac remodeling and failure. @CircAHA. #NatMetabPicks
ahajournals.org/doi/10.1161/…
