@Dr_BillyWN

Post-doctoral #ComputationalChemistry #Researcher working in #DrugDesign and #MaterialsModelling - bridging the gap between chemical theory and application.

Joined February 2021
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  • Following1.5K
  • Followers515
97Media
"Lipid trapping slows ball-and-chain inactivation in a calcium-activated potassium channel" 👇 nature.com/articles/s41467-0…
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Worth the read: linkedin.com/posts/paul-youn…

Research funding in Australia falters - ABC listen | Paul Young

Thanks to the Australian Broadcasting Corporation (ABC) and the Science Show for airing the appalling state of science research funding in Australia. And thank you Gina Ravenscroft and Dr Shane...

linkedin.com
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New paper! 👇 🎉🎉 nature.com/articles/s41467-0… #chronicpain #opioids #MolecularDynamics
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🚨NEW PAPER🚨 Well done to everyone involved - was a privilege to contribute to this work. "Computational Lipidomics Reveals Environment-Specific Membrane Remodeling in Prostate Cancer" 👇 pubs.acs.org/doi/10.1021/acs…

Computational Lipidomics Reveals Environment-Specific Membrane Remodeling in Prostate Cancer

Abstract. Metabolic changes during cancer progression produce key differences in phospholipid distributions among normal (RWPE-1), benign hyperplasia (BPH-

pubs.acs.org
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I recently contributed an article to the @EurekaStreet 👇 eurekastreet.com.au/the-phd-… Of 25% of PhD graduates who get work in their field in Australia, they must eventually compete for grants with an 85-95% rejection rate. We need better public and private R&D funding/incentives.

The PhD paradox: Why Australia produces scholars it won’t employ

Australia trains more PhDs than ever before—10,000 a year—but offers few places for them to work. A system built on perverse incentives rewards universities for producing scholars it won’t employ,...

eurekastreet.com.au
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Presenting a poster at the Asia Pacific Conference of Theoretical and Computational Chemists (APATCC-11) 🤓
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Great talk on PolyConstruct @MeganOMara ! – at Kobe City Chuo Ward, Hyogo
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pubs.acs.org/doi/10.1021/acs…

PolyConstruct: Adapting Biomolecular Simulation Pipelines for Polymers with PolyBuild, PolyConf,...

Abstract. Molecular dynamics simulations are invaluable tools that provide both a molecular understanding and a means for the rational design of polymers.

pubs.acs.org
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Himeji Castle, prior to the Asia Pacific Association of Theoretical and Computational Chemists conference in Japan. Thank you @MeganOMara for funding most of this trip! #APATCC11
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Volume 4 of J. Immat. Sci. is here! 88 pages of beer-reviewed bullshit, free to read and guaranteed to please. Massive thanks to the folks at @sciencebrush for preparing our cover art! PDF (180 MB): jabde.com/wp-content/uploads…
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That's a rap! Great time at North Stradbroke Island for the SCMB Retreat!
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Thank you @MeganLOMara for organising. Looking forward to #EnhancedSampling #MolecularDynamics publications soon!
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Off to North Stradbroke Island for a UQ Structural Biology retreat! @Patrick__Sutton & Ada Quinn
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Great work everyone - especially Alexa, @PatrickCharchar, Prof Irene Yarovsky and @dr_neve
Nanoscale journal family@nanoscale_rsc26 Sep 2024
MD simulations reveal how graphitic nanoflake size & surface functionalisation affect amylin adsorption and fibril formation. Such insights could aid in managing amyloid diseases. Read the article by @dr_neve, @Dr_BillyWN, @PatrickCharchar et al. here: pubs.rsc.org/en/content/arti…
Hexagonal array on a blue background of 0s and 1s.

ALT Hexagonal array on a blue background of 0s and 1s.

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🚨New Paper🚨 #MolecularDynamics enhanced by bias exchange #metadynamics to study the #adsorption of #Amylin on #graphene surfaces. Years of work by Alexa Kamboukas and the MMS group; @PatrickCharchar Prof Irene Yarovsky and @dr_neve pubs.rsc.org/en/content/arti…

Graphitic nanoflakes modulate the structure and binding of human amylin†

Human amylin is an inherently disordered protein whose ability to form amyloid fibrils is linked to the onset of type II diabetes. Graphitic nanomaterials

pubs.rsc.org
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Excited to announce I will be starting work with Prof @MeganLOMara at @AIBNatUQ Starting September 16th. Hard at work finalising papers in my current role
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Years of effort from the @VictorChangInst team @VandenbergJamie @ChaiAnn_Ng Mark Hunter, and our collaborators @tobywilliamall1 @EmelieJFlood @Dr_BillyWN Karen Corbett, @alastairstewart @eperozo_
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🚨 New Paper 🚨 "Potassium dependent structural changes in the selectivity filter of #HERG potassium channels" 👇 nature.com/articles/s41467-0… Well done @tobywilliamall1, @VandenbergJamie @EmelieJFlood @alastairstewart and everyone! #EnhancedSampling #MolecularDynamics #HerG #CryoEM

Potassium dependent structural changes in the selectivity filter of HERG potassium channels

Nature Communications - HERG channel inactivation is critical for normal heart rhythm. Authors determine structures of open and non-conducting states of HERG and identify a key role for S620 on the...

nature.com
Chai Ng@ChaiAnn_Ng29 Aug 2024
A significant effort to understand the rapid inactivation of hERG channels lead by @VandenbergJamie @CarusL Mark Hunter and our collaborators @tobywilliamall1 @EmelieJFlood @Dr_BillyWN Karen Corbett, @alastairstewart Eduardo Perozo. Exciting times ahead! rdcu.be/dSl0r
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Well done to everyone involved, and for the years of work invested by everyone!
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More papers to come soon! Thank you @NatureComms for hosting this one
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