@DuchenLab

Understanding the interrelationships between calcium signaling, mitochondria and free radicals in cell physiology and pathophysiology / @uclbiosciences / @UCL.

 London, United Kingdom
mitochondria.cs.ucl.ac.uk/the_duchen_lab/
Joined July 2020
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10Media
It’s World Mitochondrial Disease Week, and we’re bringing together relevant content across our journals to highlight the importance of this field. Read more from @michael_duchen in our news item, and discover our journal content below. biochemistry.org/about-us/ne…
Image of mitochondria

ALT Image of mitochondria

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@Michael_Duchen’s lab, with @RobPitceathly (@UCLIoN) and Claudio Raimondi (@QMULWHRI), has a grant from The British Heart Foundation focused on inter-relations between atypical #strokes, #mitochondrial #DNA mutations & vascular endothelial function. @thebhf @ucl #cardio
Photo of Dr Michael Duchen of the Department of Cell & Developmental Biology at UCL

ALT Photo of Dr Michael Duchen of the Department of Cell & Developmental Biology at UCL

Logo of the British Heart Foundation - three, concentric red, block-filled discs with the heart/pulse logo in white in the centre

ALT Logo of the British Heart Foundation - three, concentric red, block-filled discs with the heart/pulse logo in white in the centre

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🎓🥳 Huge congratulations to Dr. Rob Tidswell on earning his well-deserved PhD degree! 🎉👏 Wishing you continued success as you embark on this exciting new chapter in your career! 🚀
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Duchen and Szabadkai labs basking in the summer vibes while taking a well-deserved day off in beautiful London! ☀️🌸
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Wrapping up an engaging couple of days with a presentation by our final year PhD student @GabboV introducing his latest data on #mtDNA point mutations in human iPSC derived myofibers #iPSC #mitochondria Now on to the wine to celebrate🍷
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Great talk by @ChiHaoyu on his #PhD project modelling Down syndrome associated Alzheimer’s Disease using patient derived NPCs #mitochondria #iPSCs @uclcdb
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Our PhD student @ChackoAnitta opening today’s Postgraduate Research Symposium @uclcdb presenting her work on “Investigating the impact of mtDNA point mutations using patient fibroblasts and hiPSC derived neuronal models”
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Inspiring talk from @DuchenLab in #keynote seminars @IPMC_sophia @cnrs
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Thank you to everyone who attended our @uclcdb social yesterday and made it a great one! Here are some pictures of the event @DuchenLab & @SzabadkaiLab
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Congratulations @ChackoAnitta for this well-deserved recognition!
Anitta R Chacko@ChackoAnitta23 May 2023
Thank you to all the board members of the @BFWGraduates for organising such a great RPD event. I thoroughly enjoyed the day listening to all the great presentations and the discussions that followed. I'm also delighted to have been awarded the 1st prize for my presentation 😀
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We are delighted to present The Keilin Memorial Lecture to Professor Michael Duchen in 2024! @michael_duchen’s work currently focuses on the dialogue between cell signalling pathways in mitochondria, and the roles of mitochondrial dysfunction in disease.
The Biochemical Society 2024 Awards. The Keilin Memorial Lecture. Professor Michael Duchen University College London, UK.

ALT The Biochemical Society 2024 Awards. The Keilin Memorial Lecture. Professor Michael Duchen University College London, UK.

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IoN UCL PubMed: PolyQ length-dependent metabolic alterations and DNA damage drive human astrocyte dysfunction in Huntington's disease dlvr.it/Sm8l9X

PolyQ length-dependent metabolic alterations and DNA damage drive human astrocyte dysfunction in...

Huntington's Disease (HD) is a neurodegenerative disease caused by a polyglutamine (polyQ) expansion in the Huntingtin gene. Astrocyte dysfunction is known to contribute to HD pathology, however our...

pubmed.ncbi.nlm.nih.gov
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Thanks for the invite @MitOtalks, really looking forward to it! @LondonMito @MRCMitoCluster @UCL_QS_CNMD @UCLIoN @ICGNMD
MITOtalks@MitOtalks31 Mar 2023
Our next MITOtalk is approaching, and Robert Pitceathly will tell us about mitochondrial diseases and how to diagnose them. Thursday, 17h00 CET.
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Our #BogueFellowship recipient, @GabboV, had an unforgettable experience taking part in an exchange at @Harvard. Read more about his experiences here. ucl.ac.uk/lifesciences-facul…
Gardens at Harvard.

ALT Gardens at Harvard.

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Really excited to have been awarded the Bogue fellowship allowing me to spend 3months in @DrWilliamHwang ’s lab at Harvard. The Bogue fellowship generously funds PhD students/post docs to travel to the US for research or courses. @SzabadkaiLab @UmberCheema @michael_duchen
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Fantastic to be joined by #mito researchers from across @ucl to celebrate word mitochondrial disease week. #WMDW #lightupformito @UCLBrainScience @DuchenLab @UCLchildhealth @4Lilyfoundation ucl.ac.uk/ion/news/2022/sep/…
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It’s over 34 years since the first cause of mitochondrial myopathy was identified @LondonMito by Holt, Morgan-Hughes, and the late Prof Anita Harding. Since then 100s of causes have been identified but we still lack a cure. #mitoawarenessweek #WMDW @4Lilyfoundation @MitoAware
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