Associate Professor @universitelaval PI of the EdeLab, CoFounder @prideinmicro, Leader @LeafHopeCan #CRC in Insect Vectors Invasions and Emerging Plant Diseases
Québec, Canada
Joined July 2013
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How does the clubroot pathogen evolve to overcome crop resistance? A global question needed a global collaboration 🌍🧬
Four years ago, this project started with a simple question: Could we bring isolates from other countries into our lab? Luckily, many colleagues from over 20 countries around the world said yes!
Together with Stephen Strelkov and Maxim Prokchorchik, we combined three datasets: 192 isolates from 24 countries and 53 chromosome-level genome assemblies, forming the most comprehensive Plasmodiophora brassicae pangenome to date.
This work, led and central to @asimjaved777 (Bravo 🥳! #ProudPI), with major contributions from Florent, Sandra Gomez, @SohamBio, and many more, reveals:
🧬 Clonal expansion alongside genomic evidence of recombination, consistent with sexual reproduction.
🧬 A hotspot of structural variation and ankyrin-repeat effector diversification on chromosome 17.
🧬 Differences in predicted effector structures and host interactions associated with CRa resistance breakdown.
And chaperones are back in the spotlight! The identification of co-chaperone DJC31 as a candidate effector target builds on our earlier work highlighting ankyrins as a dominant effector family, targeting host translation machinery (See: elifesciences.org/articles/1…).
The main message: even a compact, highly conserved pathogen genome can hold considerable potential for adaptation, with consequences for resistance durability.
This effort received essential support through the CARP program by @canolacouncil funded by @AlbertaCanola , @ManitobaCanola, @SaskOilseeds, and @westerngrains. By @RDARAlberta , @NSERC_CRSNG Discovery and Alliance Programs, Génome Québec Programme d’intégration de la génomique, and by @BioplatformsAus / NCRIS.
Thank you to everyone who made it possible! The final database and sequences will be publicly available upon manuscript acceptance.
Now begin The Hunger Games, a.k.a. The Submission and Revisions Game. 😅 We don’t know where this paper will land, but we are incredibly proud of what we built together.
Link to preprint 🔗 : biorxiv.org/content/10.64898…
ALT overview of main findings
Edel Pérez-López retweeted
Super happy our collaborative research is out on BioRxiv. We looked at the global diversity of the clubroot pathogen and found how it adapts to resistant crop deployment. As usual, Australian isolates are unique in their own ways. We will dig into their phylogenomics further soon
How does the clubroot pathogen evolve to overcome crop resistance? A global question needed a global collaboration 🌍🧬
Four years ago, this project started with a simple question: Could we bring isolates from other countries into our lab? Luckily, many colleagues from over 20 countries around the world said yes!
Together with Stephen Strelkov and Maxim Prokchorchik, we combined three datasets: 192 isolates from 24 countries and 53 chromosome-level genome assemblies, forming the most comprehensive Plasmodiophora brassicae pangenome to date.
This work, led and central to @asimjaved777 (Bravo 🥳! #ProudPI), with major contributions from Florent, Sandra Gomez, @SohamBio, and many more, reveals:
🧬 Clonal expansion alongside genomic evidence of recombination, consistent with sexual reproduction.
🧬 A hotspot of structural variation and ankyrin-repeat effector diversification on chromosome 17.
🧬 Differences in predicted effector structures and host interactions associated with CRa resistance breakdown.
And chaperones are back in the spotlight! The identification of co-chaperone DJC31 as a candidate effector target builds on our earlier work highlighting ankyrins as a dominant effector family, targeting host translation machinery (See: elifesciences.org/articles/1…).
The main message: even a compact, highly conserved pathogen genome can hold considerable potential for adaptation, with consequences for resistance durability.
This effort received essential support through the CARP program by @canolacouncil funded by @AlbertaCanola , @ManitobaCanola, @SaskOilseeds, and @westerngrains. By @RDARAlberta , @NSERC_CRSNG Discovery and Alliance Programs, Génome Québec Programme d’intégration de la génomique, and by @BioplatformsAus / NCRIS.
Thank you to everyone who made it possible! The final database and sequences will be publicly available upon manuscript acceptance.
Now begin The Hunger Games, a.k.a. The Submission and Revisions Game. 😅 We don’t know where this paper will land, but we are incredibly proud of what we built together.
Link to preprint 🔗 : biorxiv.org/content/10.64898…
ALT overview of main findings
Edel Pérez-López retweeted
It is a pleasure to work together with Edel Perez-Lopez (@Edel_PLopez) and Stephen Strelkov. I am grateful to all the collaborators, the support from SIA (@SiaSydney), SOLES (@SydneySOLES ), Bioplatforms (@BioplatformsAus ) and the Australian growers who shared diseased plants
On top of the $10 400? 🫠
Cell Press investigating editor-in-chief accused of soliciting bribes from authors.
scmp.com/news/china/science/…
Edel Pérez-López retweeted
Great to see this work finally out! This study should serve as a helpful resource in better understanding the clubroot virulence. Cheers to @asimjaved777 and @Edel_PLopez for leading this global effort.
How does the clubroot pathogen evolve to overcome crop resistance? A global question needed a global collaboration 🌍🧬
Four years ago, this project started with a simple question: Could we bring isolates from other countries into our lab? Luckily, many colleagues from over 20 countries around the world said yes!
Together with Stephen Strelkov and Maxim Prokchorchik, we combined three datasets: 192 isolates from 24 countries and 53 chromosome-level genome assemblies, forming the most comprehensive Plasmodiophora brassicae pangenome to date.
This work, led and central to @asimjaved777 (Bravo 🥳! #ProudPI), with major contributions from Florent, Sandra Gomez, @SohamBio, and many more, reveals:
🧬 Clonal expansion alongside genomic evidence of recombination, consistent with sexual reproduction.
🧬 A hotspot of structural variation and ankyrin-repeat effector diversification on chromosome 17.
🧬 Differences in predicted effector structures and host interactions associated with CRa resistance breakdown.
And chaperones are back in the spotlight! The identification of co-chaperone DJC31 as a candidate effector target builds on our earlier work highlighting ankyrins as a dominant effector family, targeting host translation machinery (See: elifesciences.org/articles/1…).
The main message: even a compact, highly conserved pathogen genome can hold considerable potential for adaptation, with consequences for resistance durability.
This effort received essential support through the CARP program by @canolacouncil funded by @AlbertaCanola , @ManitobaCanola, @SaskOilseeds, and @westerngrains. By @RDARAlberta , @NSERC_CRSNG Discovery and Alliance Programs, Génome Québec Programme d’intégration de la génomique, and by @BioplatformsAus / NCRIS.
Thank you to everyone who made it possible! The final database and sequences will be publicly available upon manuscript acceptance.
Now begin The Hunger Games, a.k.a. The Submission and Revisions Game. 😅 We don’t know where this paper will land, but we are incredibly proud of what we built together.
Link to preprint 🔗 : biorxiv.org/content/10.64898…
ALT overview of main findings
Edel Pérez-López retweeted
When farmers come together, they grow more than just grain-they grow hope! Thank you to all the local growers and ag businesses that participated in the #VegrevilleGrowingProject to produce 10,375 bu of barley on 115 acres of land for the @Foodgrains. This is #CdnAg at its best!
Had a great time sharing ideas (but mostly learning!) about how we can move innovation from the lab to the table! 🌱🔬🍽️
A real challenge for those of us up in the ivory tower (just kidding, I haven’t made it up there yet! 😅).
A huge thank you to @CamiDRyan for being such an awesome moderator, and to @CropLifeCanada for organizing this fantastic panel and inviting me to be part of the conversation!
Already looking forward to #AmericasAgForum27! 🚀
#AmericasAgForum26
New preprint alert ! 🚨
Our collaboration with the Nunavik Sentinels program keeps delivering fascinating discoveries!
In our latest preprint, led by Florent Sylvestre, we reconstructed 8 complete mitochondrial genomes from insects collected across the Eastern Canadian Arctic, including 7 leafhopper lineages and one (very unexpected) parasitoid fly.
These discoveries remind us how much remains unknown about northern ecosystems, and why documenting biodiversity is essential as climate change reshapes the Arctic ❄️
📖 Read our new preprint: biorxiv.org/content/10.64898…
ALT Parasitoids fly
Edel Pérez-López retweeted
A great first day at the Spanish Society of Plant Pathology Congress @SEFitopatologia in Palma de Mallorca! Happy to reconnect with colleagues and friends, meet new people and share our enthusiasm for plant pathology and mycology!
#PlantPathology #Mycology
Edel Pérez-López retweeted
We're receiving corn into the clinic with ear and stalk rots. This week we speak with Tamra Jackson-Ziems and Kyle Broderick of Nebraska Extension. youtube.com/watch?v=drONbou0…
Edel Pérez-López retweeted
Root-associated bacteria alleviate iron deficiency across diverse soil pH conditions through interactions with plant-derived coumarins that promote iron mobilization via siderophore-mediated chelation or reduction-based pathways.
cell.com/cell/fulltext/S0092…
Edel Pérez-López retweeted
A beautiful example of what happens when farmers and ag businesses offer their time, resources and generosity to help feed the hungry. @Foodgrains #VegrevilleGrowingProject
Edel Pérez-López retweeted
“Farmers *can* adapt and adopt but they have to see a return on that investment.” Keith Currie, @curb1961 #AmericasAgForum26
Edel Pérez-López retweeted
📣 JOB ALERT 🎯
The Department of Entomology at Cornell University has an open position for an Assistant Professor specializing in Applied Insect Chemistry at Cornell AgriTech.
Here is the the link for the full job description and for applying
academicjobsonline.org/ajo/j…
Edel Pérez-López retweeted
Honoured to share the stage with you, Edel, and to learn from your insights!
Edel Pérez-López retweeted
Our very own Ian Affleck, vice-president, plant biotechnology & sustainability, joins @Edel_PLopez and @CamiDRyan tomorrow on a food security and innovation panel as part of #AmericasAgForum26.
Food security is national security! 🌱🇨🇦
This has been one of the central messages of this year’s #AmericasAgForum26, taking place at our beautiful @universitelaval! 👏
Tomorrow, I’m excited to join @CropLifeCanada, @Bayer, and @CamiDRyan for a panel discussion on how innovation can help shape the future of agriculture, strengthen food security, and address the challenges facing our food systems.
Looking forward to an engaging conversation! 🌎🌾
Food security is national security! 🌱🇨🇦
This has been one of the central messages of this year’s #AmericasAgForum26, taking place at our beautiful @universitelaval! 👏
Tomorrow, I’m excited to join @CropLifeCanada, @Bayer, and @CamiDRyan for a panel discussion on how innovation can help shape the future of agriculture, strengthen food security, and address the challenges facing our food systems.
Looking forward to an engaging conversation! 🌎🌾