Computational Biologist @ Patch Bio. regulatory DNA, RNA | gene therapy | synthetic biology My ''professional'' twitter account. She/her.

New York
Joined October 2014
Excited to share our recent work at @Ginkgo . TLDR: high quality mRNA stability data -> performant ML models -> design 3’UTRs that increase stability -> in vivo validated ML 3’UTRs beat benchmark. biorxiv.org/content/10.1101/…
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Elise Flynn retweeted
🚨Our work on multi-modal, single-cell pooled CRISPR screens to study GWAS variant-to-function, STING-seq, is now out in @ScienceMagazine! Read on for 6⃣ of the main findings from our study, led by myself and co-advised by @nevillesanjana and @tuuliel! 🎉 science.org/doi/10.1126/scie…
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Elise Flynn retweeted
Our newest chapter is out @nature! - Bestrophin-2 and glutamine synthetase form a complex for glutamate release nature.com/articles/s41586-0…
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Great meeting of the @GeneticsSociety Program Committee! It was an intense 1.5 days but we have an exciting program coming up for you. See you all in Los Angeles in October. – at North Bethesda, MD
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Which transcription factors (TF) regulate which #genetic variants? Flynn et al analyze eQTL effect size as a function of TF level, & find candidate TF mechanisms for a large number of eQTLs @EliseScience @tuuliel_lab @Pejminister @nygenome doi.org/10.1371/journal.pgen…
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@nickgiangreco from the @nicktatonetti lab will have his #ThesisDefense at 9 AM!
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Congratulations to Dr. Manny Tamargo @MATamargo for successfully defending his Ph.D. thesis yesterday in front of a great hybrid crowd of lab mates, family, and friends!! We are so proud & wish you the best of luck in the future.
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Fed prosecutors in Brooklyn are inexplicably seeking a terrorism enhancement for two people w/no record that could mean 10 yrs in a case of property damage to an abandoned police vehicle that should have never been a federal case in the first place.
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Tell us your favorite Thanksgiving dish, and we’ll share some of what we know about the work behind the ingredients. #WeFeedYou #ThankAFarmworker
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Keep calm. Be patient. Allow local elections officials to do their jobs. What is most important isn’t the speed of the count; it’s that every eligible vote is counted. Americans made their voices heard in record numbers, and their votes must be counted. #Election2020
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Very happy and proud to present: The GTEx papers. This set of 15 papers published today describes the final phase of this 10-year effort, providing the genomics community an atlas of genetic regulatory variants and a deep dive into the biology behind it. sciencemag.org/collections/g…
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In addition to my main GTEx thread, I’d like to highlight some of the work & companion papers from my lab by these awesome folks: @skimhellmuth @silvakasela Margot Brandt, @EinsonJ, @EliseScience @stephanecastel. xitter.cf/tuuliel/status/1304121…
Very happy and proud to present: The GTEx papers. This set of 15 papers published today describes the final phase of this 10-year effort, providing the genomics community an atlas of genetic regulatory variants and a deep dive into the biology behind it. sciencemag.org/collections/g…
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Our lab is looking for an outstanding experimental postdoc to help develop the next generation of biomolecular profiling in a joint project with @NShahLab. See tinyurl.com/y8ulgwps for details. @Chemjobber #postdocpositions
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Must read by my amazing friend @phenomenonny. Her own traumatic experience of being mistakenly pulled over with her mother, at gunpoint, by police officers using The Stolen Car Excuse. Unacceptable, yet it happens far too often when Driving While Black. washingtonpost.com/lifestyle…
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In response to this tweet + article I tried something new: I posted a request for questions from my friends and family on Facebook. In less than 24 the post has 110 comments and 17 shares. People I’ve never met are asking questions and my colleagues are jumping in to help answer
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🗣🗣🗣 Colin Mattis & his co-defendant @UroojRahman_is are heading home until trial! The United States Court of Appeals for the Second Circuit affirmed the district court’s order that both defendants be released on bail! Thank you all for your thoughts, prayers, & support.
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Replying to @simplelogical
Science does not transcend any of these things. It is not some magical thing - science is a bunch of humans figuring stuff out. Some of them are wonderful, others not. We can all do with a day now and again to turn our critical thinking into ourselves.
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For academics (especially White academics, but this goes for everyone) reading #BlackintheIvory and wondering how you can support Black students and academics here is a thread of things to consider a number which have been especially supportive of my own professional development
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Elise Flynn retweeted
White people: We gotta talk about burn out. You aren’t conditioned to be thinking about race this much because of your privilege. We need you to do all you’re doing today, tomorrow, and until the end of time. Let’s talk about ways to focus on current & systemic change. 👇🏽
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