@EmmaScienceLady

PhD student #CornellPPPMB in the Pawlowska lab studying fungal-bacterial interactions and endosymbiosis 🍄‍🟫🧫🫂💖 Follow me on BlueSky!!! @emmascales

Joined July 2024
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No joke! Pseudomonas viridiflava naturally infects wild Marchantia. Now published in @CurrentBiology. Led by Kayla Robinson with @LuciaBuric, Kris Grenz, @Khongsam_Chia from our group @JohnInnesCentre, and @michhulin & @wenboEffector from @TheSainsburyLab -sciencedirect.com/science/ar…
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Had a great time presenting last week at #CornellSIPS Decennial Symposium, and was glad to see #CornellPPPMB out in full force. Some of the lab made it out, too! Also lucky to check out the functional genomics work of @moldymicrobe and the rad entomopathogen work of @alexlando_
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Um, ya, so clearly my photos didn't come out very good, but look at this absolutely freaky fungus! Credit to @chasemayers who co-teaches the fabulous mycology class I'm in this semester = ) #mycology #penicillium #FungiFriday #CornellPPPMB
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Excellent @cornellASAP event last week with Nancy Jacobson from @citizensclimate NY Southern Tier and Finger Lakes Chapter, explaining their ongoing bipartisan climate advocacy work, and ways for members and others from the @CornellGrad community to get involved!
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Chapter 2: “Mapping the uncharted territories of human brain malignancies” This chapter includes the preview @LeilaAkkari1 and I wrote on two papers that extensively analysed the immune landscape of various brain malignancies cell.com/cell/fulltext/S0092…
How do different brain malignancies (represented here as a distant temple on brain tissue) uniquely impact the recruitment of immune cells? This previously uncharted territory was extensively mapped in two papers published in Cell (Friebel et al. and Klemm et al., 2020), for which Leila Akkari and I wrote a preview back in 2020. The vines represent myelinated neurons, emphasizing the unique “flora” of the brain. A macrophage is holding a map, often the first cell type recruited by the tumor, followed by T-cells (green) and dendritic cells (yellow). The erythrocytes at the campfire symbolize the recruitment of immune cells from the blood through inflammation.

ALT How do different brain malignancies (represented here as a distant temple on brain tissue) uniquely impact the recruitment of immune cells? This previously uncharted territory was extensively mapped in two papers published in Cell (Friebel et al. and Klemm et al., 2020), for which Leila Akkari and I wrote a preview back in 2020. The vines represent myelinated neurons, emphasizing the unique “flora” of the brain. A macrophage is holding a map, often the first cell type recruited by the tumor, followed by T-cells (green) and dendritic cells (yellow). The erythrocytes at the campfire symbolize the recruitment of immune cells from the blood through inflammation.

Daan J. Kloosterman@djkloosterman1 Oct 2024
After designing the cover submission for our Cell paper, I got inspired to make illustrations for each chapter of my #PhD thesis. Chapter 1: “An introduction to #macrophage education and #targeting in brain cancer” Thinking of sharing each illustration for my 9 chapters🤔
Macrophages partake a central role in tumor progression. Understanding the inter- and intra-tumoral heterogeneity of macrophages will be important for the rational design of tailored therapeutic strategies to target pro-tumorigenic macrophages. The phenotype of macrophages is highly plastic and influenced by its ontogeny (top left panel), the organ in which it resides (top right panel), the tumor (bottom left panel), local niche and cellular interactions (bottom right panel).

ALT Macrophages partake a central role in tumor progression. Understanding the inter- and intra-tumoral heterogeneity of macrophages will be important for the rational design of tailored therapeutic strategies to target pro-tumorigenic macrophages. The phenotype of macrophages is highly plastic and influenced by its ontogeny (top left panel), the organ in which it resides (top right panel), the tumor (bottom left panel), local niche and cellular interactions (bottom right panel).

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It had to be done
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Emma Scales retweeted
Cornell Advancing Science and Policy Club (ASAP)@cornellASAP22 Jul 2024
How to Make Science a Priority for Candidates secure.ucsusa.org/a/2024-7-2… Join us for this webinar on Thursday @ 3 p.m. ET
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Supplemental video from our @PLOSBiology paper showing the MMB exhibiting #magnetotaxis in a hanging water droplet. @environmicrobio
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I'm not gonna lie, I love the idea that bright blue crayfish are that hue just because. Or, as one researcher put it, a "happy evolutionary accident." That story and more of the best from @ScienceMagazine and science in this edition of #ScienceAdviser: science.org/content/article/…
This blue beauty spends most of its time underground. So why the hue? ZACK GRAHAM

ALT This blue beauty spends most of its time underground. So why the hue? ZACK GRAHAM

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Check out our latest @biorxivpreprint! Over the last years, we have identified and characterised several effector proteins of fungal pathogens that display antimicrobial activity. How many such antimicrobials do fungi encode? Fantastic work by @f_mesny 👇
Fantin Mesny@f_mesny5 Jan 2024
NEW PREPRINT, NEW SOFTWARE We (@Team_Thomma) are delighted to announce the release of AMAPEC, an accurate antimicrobial activity predictor for fungal effector proteins. 📰: biorxiv.org/content/10.1101/… 💻: github.com/fantin-mesny/amap… 👇🏼
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It was great seeing colleagues Emma Scales and Alex Lando present at CIHMID Research Symposium 2024 today! @cihmid #CornellPPPMB
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