Enhancer papers manually picked by @IvKrivega. Views are my own. #chromatin #enhancer #synteticbiology #geneediting
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Joined July 2020
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loop_enhancer retweeted
@Kaepernick7 didn’t kill anyone with his stance and he got blackballed. Aaron Rodgers acted recklessly with no penalty. How is this fair??
loop_enhancer retweeted
6.) We also identified large contiguous H3K27ac domains reminiscent of but distinct from super-enhancers that appear to seed intra-TAD interactions and A-compartmens in early developmental stages. (8/n) (​​@EnhancerLoop, @generegulation 👀)
ALT Schematic for the proposed regulation. Top: a long H3K27ac signal. Middle: bystander genes and HCNEs interacting with a target gene indicated through arrows. Bottom: Hi-C based TAD triangle enclosing the regulatory block.
ALT Schematics of the proposed model how the GRB TADS work during development. only weak TADs pre-mzt (top). strong transcription mainly of genes in TADs with an enhancer ensembl close-by (middle). At late post-mzt, single enhancer have formed as well as strong TADs (bottom).
loop_enhancer retweeted
HiC maps and wine. What can be better? Some weird structures in Napa valley though
loop_enhancer retweeted
Troubles with calling A/B-compartments from Hi-C data due to telomere-centromere clustering (Rabl-configuration), mis-assemblies, polymorphic inversions or large heterochromatin blocks? Check our latest release of the ABCE algorithm solving these problems: github.com/NuriddinovMA/ABCE
