@Equipe_lenne

@pflenne@mas.to Physical approaches to cell dynamics and tissue morphogenesis

 Marseille, Luminy Campus
morphotiss.org/
Joined November 2013
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How do cell-cell contacts remodel in vivo? Together with the team of JF Rupprecht @JFRupprecht_OM, we address this question here: doi.org/10.1073/pnas.2212389…
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See you under another sky... @pflenne.bsky.social
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🥳 Exciting news! Thrilled to announce my new lab at @IBDMmarseille @cnrs. 🎉 We use #LiveImaging to study how the dynamic #ovary makes healthy #eggs. 🔬🥚 Please RT & follow as we push the boundaries of #Fertility research! 🔗 bit.ly/3zQPEh7 #AcademicTwitter #NewPI
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🚨📢Our paper on imaging, segmenting, visualising and measuring patterns in gastruloids across spatial scales w/ @napari_imaging is out‼️ An project led by @_AliceGros, @JVanaret, @DunsingValentin et al.🤓 A collab. between @Equipe_lenne, @PhilippeRoudot's and our lab. ⬇️Link⬇️
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New preprint: We have developed an integrated pipeline to i) image gastruloids in toto with dual-view 2-photon🔬, ii) quantitatify cell and tissue-scale patterns of gene expression and morphometric features, iii) interact with the data in @napari_imaging. biorxiv.org/content/10.1101/…
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📢 Join us and present your work at the 2024 Condensed Matter Days in Marseille, France, Oct 28-31, for a mini-colloquium: "Phase transitions in biology: Liquid-liquid phase separation in the nucleus and tissue remodeling" organized by J-M Victor and myself.
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More details: jmc2024.sciencesconf.org/dat… Deadline: Oral talks - June 21, Posters - Sept 15 jmc2024.sciencesconf.org/res…
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Insightful perspectives on the role of mechanics in embryogenesis. Glad to contribute to this collective scientific endeavor. nature.com/articles/d41586-0…

Push and pull: how to measure the forces that sculpt embryos

Nature - A steadily growing toolbox is giving researchers the ability to monitor and measure the physical forces that shape embryonic development.

nature.com
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The registration deadline for PLM has been extended to this Friday, May 31st. This is your last chance to decide to join us at the beautiful Palais du Pharo in Marseille in September!
CENTURI - Turing Centre for Living Systems@centuri_ls27 Feb 2024
🏹 #PLM18 Registrations are open for the 18th edition of the Physics of Living Matter #conference ! 📍 Where: Palais du Pharo, Marseille 📆When: September 16-17, 2024 🖊️Registration deadline: May 16, 2024 More info: centuri-livingsystems.org/pl… @univamu
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3 days left to register for the "Physics of Living Matter" conference to be held in Marseille in September! Don't miss the deadline!
CENTURI - Turing Centre for Living Systems@centuri_ls27 Feb 2024
🏹 #PLM18 Registrations are open for the 18th edition of the Physics of Living Matter #conference ! 📍 Where: Palais du Pharo, Marseille 📆When: September 16-17, 2024 🖊️Registration deadline: May 16, 2024 More info: centuri-livingsystems.org/pl… @univamu
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1/n We are very pleased to see our study on Wnt spreading in C. elegans embryos published in @CurrentBiology cell.com/current-biology/ful… . The outcome of an exciting collaboration between Vincent Bertrand's team and our team. A short thread on our main results!
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8/n Our study shows how freely diffusing Wnt ligands can quickly convey long-range polarity signals during embryonic development solely through extracellular diffusion. Excited to share!
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9/9 Big thanks to all! 🌟 @PRecouvreux, Pritha Pai, @DunsingValentin, Remy Torro, Mónika Ludányi, Pauline Mélénec, Mariem Boughzala, Vincent Bertrand and @Equipe_lenne. @IBDMmarseille, @centuri_ls, @univamu
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a 100X accelerated project!
Valentin Dunsing-Eichenauer@DunsingValentin28 Mar 2024
Just presented at #FOM2024 and now available to read: We accelerate FLIM by a factor of 10-100 using single objective light-sheet microscopy and SPAD array detection. This allows us to do 3D (time-lapse) FLIM on organoids and lifetime unmixed imaging. biorxiv.org/content/10.1101/…

Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective...

Fluorescence lifetime imaging (FLIM) is widely used for functional and multiplexed bioimaging, but is limited in speed, volumetric sampling of multicellular specimen, and live cell compatibility. To...

biorxiv.org
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We revisited the zonula adherens in intestinal epithelia using superresolution microscopy. Great work of Pierre Mangeol (@PierreMangeol) in a fruitful collaboration with André Le Bivic's team! Check it out: pnas.org/doi/10.1073/pnas.23…

The zonula adherens matura redefines the apical junction of intestinal epithelia | PNAS

Cell–cell apical junctions of epithelia consist of multiprotein complexes that organize as belts regulating cell–cell adhesion, permeability, and m...

pnas.org
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