We use genetics and genomics to understand neurodegenerative diseases. We also use modern approaches to develop more predictive models for Alzheimer's disease.

The Jackson Lab, Bar Harbor ME
Joined March 2016
Three is the magic number (for posters at #AAIC23)! Visit Stacey Rizzo from the @RizzoLab to learn more about animal models for late onset #Alzheimers disease being developed by the @IndianaUniv @jacksonlab @PittTweet @Model_ad_alz Consortium #EndAlz
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Phenomenal talk by @kateeeemily today at #AAIC23 exploring the glial influence on exacerbating ARIA in AD mouse models. Exciting findings and looking forward to seeing where this work goes!
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Stop by Posters 43 & 44 to chat with @MayoClinicNeuro’s Joseph Reddy and @jacksonlab’s Asli Uyar about their work using resources from the #Alzheimers Disease Knowledge Portal and @Model_ad_alz to help #EndAlz #AAIC23 @NIHAging
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Headed off for a long travel day to Amsterdam for #AAIC23! Excited to be presenting so very cool work (with new data 🥳) that I’ve been working on with @ErikBloss and @garethhowell10! Make sure to come by my poster on Tuesday P3-012 to learn more!
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It will be drop the mike time for @cowabunga314 and I!
To close out the #AAIC23 make sure to check out the Thursday Genetics, Biomarkers and Endophenotypes in AD mouse models session, co-chaired by the amazing @cowabunga314! Featuring talks by my mentor @garethhowell10 and @cowabunga314!
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Biggest contingent of @GHowell_Lab @jacksonlab at #AAIC23 ever! See presentations from @cowabunga314, @Heuerwego, Alaina Reagan, Olivia Marola and I. APOE, microglia and synapses, vascular health, toxic metals, the eye as a biomarker, and genetic diversity - something for all!
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Check out presentations by former @GHowell_Lab @jacksonlab members @kateeeemily and @Becca__Buchanan at #AAIC23. The Howell lab network spreads.
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Replying to @CarterLabJax
@CarterLabJax’s Catrina Spruce, @GMilinkeviciute, and @garethhowell10 of @Model_ad_alz fame with the biodomains board at the @NIH Pavilion. Check it out and learn more about the #FreeData, animal models, and experimental tools available at booth 212! #EndAlz #AAIC23
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Stop by Asli’s from ⁦@gwcarter⁩ lab and ⁦@cowabunga314⁩ ⁦@GHowell_Lab⁩ poster at P2-043 showing how mouse genetic diversity differentially regulates brain aging and response to amyloid.
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Check out AARF grant awardee Olivia Marola @GHowell_Lab @GHowell_Lab @jacksonlab poster (P2-029) on studying the role of the ANG/TIE2 in vascular health and ADRD using novel mouse models. #AAIC2023 #AAIC23 #EndAlz
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Introducing MODEL-EyeD at #AAIC2023 leveraging novel @Model_ad_alz and @GHowell_Lab mouse strains to evaluate the potential of the eye as and additional biomarker for AD. Poster P2-245.
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SUPER excited to share a preprint reporting some cool work I've been doing with @ErikBloss and @garethhowell10 at @jacksonlab! A 🧵...
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🎉 Celebrating #NPAW2022! Dr. Alaina Reagan is a postdoc in the @GHowell_Lab at @jacksonlab, researching how age and genomic factors influence cerebrovascular function in Alzheimer's Disease and dementia: jax.org/people/alaina-reagan #JAXTrainee
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Replying to @GHowell_Lab
@GHowell_Lab oh we did… most lab presentations included a Samuel l Jackson meme 😂
Ok, but does anyone NOT giggle when they read "MTHFR gene"?
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Stop by the @AMPADPortal @Model_ad_alz booth! We are recruiting post-docs, research scientists and graduate students! #AAIC2022 @NeurosciStark @Sagebio
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Howell Lab retweeted
Here is @RaviSPandey15 telling all your friends about AD-relevant metabolic signatures in @Model_ad_alz mouse models.
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👋 Hey #AAIC22! Did you know @jacksonlab has postbacc, Ph.D. and postdoc training opportunities in #dementia and #Alzheimers? Come chat with Meredith, Maya and Miriam to learn more! ➡️ Booth #112 ⬅️
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FINAL DAY to let the #Alzheimers research community know what you think about various hypotheses! Different colors for each day of the conference help examine the influence of #AAIC22. Visit booth 914 for today’s vote! #AAIC2022 #endalz @Model_ad_alz @alzassociation @FriendsofNIA
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