@GPBees

A prestigious journal for omics and bioinformatics areas. 20 years of excellence since 2003.

 Beijing
academic.oup.com/gpb
Joined January 2020
  • Tweets1.4K
  • Following2.7K
  • Followers555
169Media
1/5: New in GPB! How to efficiently build the tree of life for prokaryotes? Zuo introduces WebCVTree4, an alignment-free web server for whole-genome phylogeny and taxonomy, integrating 220k+ genomes. Read: doi.org/10.1093/gpbjnl/qzag0… #Phylogeny #Bioinformatics
1
1
2
66
more replies
4/5: The platform features an interactive front-end. Users can configure projects, upload genomes, dynamically adjust tree layouts, and export publication-ready figures or distance matrices for further analysis. #DataScience
1
9
5/5: WebCVTree4 provides a comprehensive, user-friendly platform for microbial evolution and taxonomy in the big-data era. It is freely accessible at: cvtree.online/ Read: doi.org/10.1093/gpbjnl/qzag0… #Phylogenetics #WebServer
8
1/5: New in GPB! How to decode long-range gene regulation at single-cell resolution? Wen et al. introduce scReGAT, a deep learning framework integrating prior knowledge to reconstruct cell-specific networks. Read: doi.org/10.1093/gpbjnl/qzag0… #scRNAseq #DeepLearning
1
1
2
53
more replies
4/5: scReGAT uncovers dynamic regulatory rewiring in neuroblastoma and osteogenic differentiation. Its scores can anticipate transcriptional transitions, revealing early upstream events guiding cell fate. #CancerResearch
1
11
5/5: scReGAT offers a robust framework for decoding gene regulation and complex disease genetics. Code: github.com/TianLab-Bioinfo/s… Read: doi.org/10.1093/gpbjnl/qzag0… #Bioinformatics
10
1/5: New in GPB! How does DNA methylation drive sexual size dimorphism (SSD)? Wang et al. reveal the spatiotemporal methylome of Chinese tongue sole, showing how methylation regulates growth and evolution. Read: doi.org/10.1093/gpbjnl/qzag0… #DNAMethylation #Genomics #evolution
1
1
1
68
more replies
4/5: Evolutionarily, rapidly evolving genes in this species show lower methylation levels than background genes. This suggests DNA methylation plays a key role in natural selection, helping organisms allocate resources between growth and reproduction. #EvolutionaryBiology
1
10
5/5: This study provides the first comprehensive multi-tissue, multi-stage methylome atlas for vertebrate SSD, offering new insights into phenotypic evolution and resource allocation.
12
1/5: New in GPB! He et al. explore integrating genomics into large birth cohorts to uncover early-life environmental and genetic impacts on maternal and child health. Read: doi.org/10.1093/gpbjnl/qzag0… #Genomics #BirthCohort

Integrating Genomic Studies into Large Birth Cohorts

Abstract. Adverse exposures during early life, including environmental and genetic factors, can have profound and long-lasting effects on health in later l

academic.oup.com
1
2
50
more replies
4/5: Challenges remain: ethical/privacy concerns, complex data integration, delayed clinical translation, loss to follow-up, and scarce multigenerational sampling. Global collaboration is needed. #Genomics #DOHaD
1
10
5/5: Large birth cohorts are key to decoding DOHaD. Integrating genomics, multi-omics, and AI will advance maternal and child health and precision prevention.
9
Load more