Lastly, our sponsor @mithrilcompute made this workshop possible!
Some of us use their platform for high-performance computing and we love the experience!
Mithril is offering compute credits (1x $10,000 org, 2x$1,000 indiv)
Apply here by May 1st: forms.gle/BhtKsWRUcQiL3o856
#ICLR2026
This wraps up the 1st Workshop on Generative AI in Genomics (Gen²) @iclr_conf.
We had so many speakers we wanted to invite, yet couldn't fit into our schedule.
We'd like to acknowledge our organizers, advisors, and colleague, @SandeepKambham2, who helped us run the workshop!
This wraps up the 1st Workshop on Generative AI in Genomics (Gen²) @iclr_conf.
We had so many speakers we wanted to invite, yet couldn't fit into our schedule.
We'd like to acknowledge our organizers, advisors, and colleague, @SandeepKambham2, who helped us run the workshop!
We’ve had 57 submissions presented in our sessions, spanning:
🧬 Diffusion models for regulatory element design
🧪 Single-cell, epi- & metagenomic foundation models
🤖 AI agents & perturbation prediction
📍 Generative spatial transcriptomics
A huge thanks to all our presenters!
Check out the accepted submissions here:
openreview.net/group?id=ICLR…
#ICLR2026, #AI4Bio, #AI4Science, #Genomics, #ComputationalBiology, #GenAI @iclr_conf
Our last talk was by
@arkosiorek
on #AlphaGenome. They noted it's not a generative model :) Yet, as a SOTA model for unified regulatory variant effect prediction, it represented the most popular application area of our submissions: regulatory genomics.
We knew this would surely be of interest to the community, and it was!
Here is a their Substack on #AlphaGenome, focusing on the biological aspects:
xitter.cf/arkosiorek/status/2020…
Publication: nature.com/articles/s41586-0…
Want to understand AlphaGenome but don't have a PhD in Biology? 📉
I joined the team without a bio background, and we just published in @Nature. Here's a breakdown for CS/ML community I wish I had: akosiorek.substack.com/p/alp…
#AlphaGenome #AI #Bioinformatics #DeepMind
Also, check out alphagenome-pytorch, an accessible and hackable port from the @pkoo562 and @anshulkundaje labs for integrating the model into native PyTorch pipelines and fine-tuning on custom datasets:
genomicsxai.github.io/blogs/…
and the thread: xitter.cf/abuen_dia/status/20318…"
Thrilled to announce alphagenome-pytorch, an accurate, readable, and careful port of AlphaGenome's architecture and weights to PyTorch. Work with @gtcaa @m_kjellberg @chriswzou @tuxinming as part of the GenomicsxAI initiative between @anshulkundaje and @pkoo562 labs.
We heard from @gokcen, who presented Nona, a masked modeling framework for functional genomics that unifies multiple modalities. Their talk was just as accessible and comprehensive as the model itself! Check our their preprint here: biorxiv.org/content/10.1101/…
Next, we had @njwfish present "Generative Distribution Embeddings" presenting his work from:
(GDE): arxiv.org/abs/2505.18150
(Distribution-Conditioned Transport; DCT): arxiv.org/abs/2603.04736
@iclr_conf #ICLR2026 #AI4Bio #Genomics #Gen2Workshop
We've kicked off our workshop with two stellar field-grounding talks with forward-looking vision from Sarah Teichmann @teichlab and Maria Brbic @mariabrbic. If you missed it, check out the recording on iclr.cc @iclr_conf #ICLR2026 #AI4Bio
Our panel discussion with Smita Krishnaswamy, Adam Kosiorek @arkosiorek, Alex Tong @AlexanderTong7, Gabriele Corso @GabriCorso and Nic Fishman @njwfish, moderated by Arnaud Doucet @ArnaudDoucet1 is now starting!
Our panel discussion with Smita Krishnaswamy, Adam Kosiorek @arkosiorek, Alex Tong @AlexanderTong7, Gabriele Corso @GabriCorso and Nic Fishman @njwfish, moderated by Arnaud Doucet @ArnaudDoucet1 is now starting!
1 week to go until our inaugural Gen² workshop at #ICLR2026 on April 27! We’re excited to share our updated schedule: genai-in-genomics.github.io/…
We’ll open with a plenary talk by Sarah Teichmann @teichlab, followed by invited keynotes from @mariabrbic, @njwfish, @gokcen, and @arkosiorek.
A big thank you to sponsor @mlfoundry for the support. The compute credits deadline has been extended to May 1, 2026, AoE: forms.gle/UGCY16ub61fpgxnG6. Looking forward to seeing many of you at the workshop!
We’re excited to highlight oral spotlight presentations by Prateek Anand, Prin Phunyaphibarn, and Qiyuan Liu, along with many exciting poster presentations. (4/5)
We’re also excited to feature a panel discussion moderated by @ArnaudDoucet1. Please fill in our question collection form here: forms.gle/yTgG5baCPMNPHWXC8 (3/5)
🚀Compute credit opportunity from our sponsor Mithril for the Gen² community: 1 org prize of $10K, 2 individual prizes of $1K. Preference for Gen² attendees, but open to all researchers. 🗓️Apply by Apr 21, 11:59 PM AoE: forms.gle/BhtKsWRUcQiL3o856



















