We are a multi-Institute UK consortium that, together, house a full range of preclinical models for GBM target validation https://xitter.cf/t.co/4N7eTbM73Y

United Kingdom
Joined January 2022
This position paper highlights the need for better experimental models, but also *better access* to a *range* of different models, for brain tumour research. The most complex organ in the human body needs a multifaceted experimental approach to understand the diseases within it!
Pledges to increase brain tumour research funding in the UK have not improved outcomes, as was hoped. Our position paper opines why "Adult brain tumour research in 2024: Status, challenges and recommendations" doi.org/10.1111/nan.12979 @KarinPurshouse @allyrooney @jenkinsonmd
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We love models, but we also love finding out about all the hugely advanced technology we can apply to learn as much as possible from them! Investigation of GBM cell plasticity NEEDS single-cell multi-omics!
If you're interested in Spatially Resolved, Single-Cell Transcriptomics & Proteomics, join us @ 2pm, Worsley 9.60 or alternatively via TEAMs for the seminar “Nanostring: Multi-Omic, Spatial Profiling at Single-Cell Resolution to Unravel Complex Biology” Speaker: Dr.Bryan Serrels
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We are excited to announce Leeds Centre for Disease Models Annual Meeting on the 8th of March@Nexus to @UniversityLeeds community. 🗣️📯🥳 Please register here: 🧑‍💻eventbrite.co.uk/e/leeds-cen… (tickets are limited)
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Microrobots in the brain Vasculature!   We use microrobots and control them wirelessly in the brain vessels (even against the flow). We are just at the beginning of this exciting field. What kind of application do you imagine? biorxiv.org/content/10.1101/… #innovation #medtech
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Great to meet with colleagues this morning to discuss all things @GlioModel . So important to bring people together from across Institutes and Universities and disciplines. @NatiGomezRoman @StrathScience @Healthcarefut #Braintumour #Glioblastoma
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Exciting news! Funded brain tumour research and a chance to further show proof of concept to get GlioModel up and running. Well done Dr Jane Alder!
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Exciting news alert 🗣️📯: we are delighted to let you know that our 2023 disease models 🧫👁️🧠🫀🫁conference will be taking place on Wednesday the 8th of March at NEXUS. Please save the date and more details to follow soon ✍🏼
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Exciting to hear @LucyFStead discuss the power of collaborating on #glioma models across the UK with @GlioModel. #BTNW #BrainTumour
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State-of-the-art experimental models need state-of-the-art analysis techniques. Out today in JBM: 'SpheroidAnalyseR—an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates' @GliomaGenomics @Rhiannon_Barrow @LucyFStead polscientific.com/jbm/index.…
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We are looking for an enthusiastic PGR to join the Leeds Centre for Disease Models Executive Committee. If you are actively involved in cellular disease models and would like to help shape this research area and community at the University of Leeds, please get in touch!
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Really great to catch up with colleagues today in @GlioModel on zoom. Superb collective who are aiming to establish validated glioblastoma models to aid in all glioblastoma research. So excited for what is ahead! Thanks to @LucyFStead for organising
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Please note that @LeedsNeuroRTB is a brain tumour tissue bank open to ALL researchers. Just email [email protected] to apply. Huge thanks to @YorkshireBTC and @OscarsCharity for facilitating so much research
Why are so many types of brain tumour incurable? How can tissue banking help? @LucyFStead told the @hippocraticpost why tissue banks like @LeedsNeuroRTB funded by YBTC & @OscarsCharity are vital to helping us find a cure hippocraticpost.com/cancer/b…
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LOOK 👀 a special research topic in @FrontCellDevBio on GLIOMA: From Genetic to Cellular Heterogeneity 🧠🧬There's so much exciting research in this area right now. Submit your abstract by 24th Sept✏️ & manuscript by 23rd Nov🖊️More info here 👉 frontiersin.org/research-top… Pls RT
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Hugely informative and entertaining talk on organoid development and assays by latest GlioModel member @jamesapoulter who was also one of the organisers for this @DIMOLeeds Organoid workshop 👌👍👏
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A full house for the @DIMOLeeds Organoid Modelling workshop starting with @linda_lako from @UniofNewcastle on her state of the art retinal organoids. A full day of exciting talks and discussion ahead @UniversityLeeds @LeedsCancerRes @LIMRLeeds
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Dr @LucyFStead explains how the @GlioModel consortium is allowing collaboration for GBM researchers across the country
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We used the opportunity, whilst in Liverpool at #BNOS22, to visit GlioModel member Prof Harish Poptani's amazing imaging setup for preclical glioma models. We see so much opportunity for sharing of these kinds of resources in our consortium to expedite target validation in GBM!
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Amr Moursi explaining how the GBM on chip model, included in GlioModel, from University of Hull can track the release of cytokines from tissue in real time. Funded by @YorkshireBTC. #BNOS2022 @BNOSofficial
Organoids are facilitating a wealth of brain research. A great model to have in our collection
Replying to @Sergiu_P_Pasca
@Sergiu_P_Pasca and I detail methods for high-resolution imaging and sub-cellular tracking of migrating neurons & calcium imaging of network activity in human forebrain assembloids! @STARProtocols star-protocols.cell.com/prot…
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