@GriffithsJess94

Postdoctoral research fellow @EdinburghUni 🔬🧠

 Edinburgh, Scotland
Joined August 2020
  • Tweets30
  • Following207
  • Followers104
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Our review on synapse pathology in Alzheimer’s disease is out! We review studies that shed light on changes in synapse architecture, discuss mechanisms of pathology, and consider how synapse diversity may impact AD progression. authors.elsevier.com/sd/arti…
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Big week for the Jackson synaptics lab last week... 1st Imperial PhD thesis submitted, presented new data at Japan-UK neuroscience meeting and we have a new preprint out...a 🧵1/6
bioRxiv Neuroscience@biorxiv_neursci23 Jan 2025
A synaptic-astrocytic proteomic signature associated with synaptopathy in Alzheimer's Disease biorxiv.org/cgi/content/shor… #biorxiv_neursci
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A fab two days in York for the annual @UKDRI ECR synapse theme event. Great scientific talks and discussions and a little sightseeing too. @UKDRI_ECR
Four of us outside York cathedral.

ALT Four of us outside York cathedral.

Winners of the ECR prizes

ALT Winners of the ECR prizes

A picture of York walls

ALT A picture of York walls

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Our review on synaptic dysfunction in Alzheimer’s disease is now out! We summarise evidence for possible synaptic dysfunction in human AD and give an overview of some animal and cellular research that supports this focusing on ephys/functional datasets. frontiersin.org/articles/10.…

Frontiers | Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during...

The synapse has consistently been considered a vulnerable and critical target within Alzheimer’s disease, and synapse loss is, to date, one of the main biolo...

frontiersin.org
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This summarises a huge team effort at map-ad.org , the majority of whom are women #InternationalWomensDay
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Jessica Griffiths retweeted
Takeshi Kaizuka@TakeshiKaizuka27 Jan 2023
My second study at RIKEN and Kobe University has been posted on bioRxiv. DRACC1, a major postsynaptic protein, regulates the condensation of postsynaptic proteins via liquid-liquid phase separation biorxiv.org/content/10.1101/…

DRACC1, a major postsynaptic protein, regulates the condensation of postsynaptic proteins via...

Numerous proteome analyses have been conducted on the postsynaptic density (PSD), a protein condensate beneath the postsynaptic membrane of excitatory synapses. Each has identified several hundred to...

biorxiv.org
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Synapse community, what do you think are the current major questions we need to address surrounding synapse pathology in neurodegeneration? #synapse #neurodegeneration #moleculestocircuits #synapticplasticity #dementia
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Excited to share this latest AD preprint led by @esbrady93! Congratulations Erica and the rest of this wonderful team that I was lucky enough to learn from and work with😊
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Thrilled that map-ad.org featured in this. Lots of hard work highlighted by our amazing team😀at @ImperialBrains and including @LabStratton @n_willumsen @drcombiz @GriffithsJess94 @SWDBrainBank and across the @UKDRI
UK Dementia Research Institute
@UKDRI1 Dec 2021
With 2021 (nearly) drawing to a close, we wanted to pick out a few highlights for the Institute as we look forward to a new year in dementia research 🎉 #⃣1 - A reflection on 5 years of @UKDRI in our brand new interactive digital brochure #2021highlights discover.ukdri.ac.uk/

Discovering hope for dementia: On track to treatments

Explore how the UK Dementia Research Institute is rising to the challenge of dementia by bringing together bright minds, top tools and creative thinking. See how our groundbreaking discovery science...

discover.ukdri.ac.uk
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Exciting opportunity to work with Kevin Fox and me on 'Cortical feedback circuits for sensory integration and control of synaptic plasticity'! This MRC funded post-doc position is for nearly 5 years - 2 weeks to apply! @CUBiosciences @neurosciencecu krb-sjobs.brassring.com/TGne…
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Jessica Griffiths retweeted
SfN Journals@SfNJournals27 Sep 2021
#SnapshotsInNeuroscience from @sledziowskam & @GriffithsJess94: The midline topographical organization of the corpus callosum of a newborn mouse, stained as part of a detailed characterization of the PCDH19 knockout mouse. Read more on the #eNeuro Blog: blog.eneuro.org/2021/09/snap…
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Jessica Griffiths retweeted
Monika Sledziowska@sledziowskam19 Aug 2021
So cool to see the article from Isabel Martinez Garay lab on the homepage of eNeuro with a beautiful image of axonal tracts. eneuro.org/content/8/4/ENEUR… @SfNJournals #NeuroTwitter
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📢JOB ALERT📢 Exciting opportunity for a postdoc to join our team @EdinburghUni at the start of a new ERC-funded project, SYNAPTOME, to uncover the synapse diversity of individual neurons in the brain🧠 🗓️9th Sept ♻️Pls RT! elxw.fa.em3.oraclecloud.com/…
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Very exciting opportunity for an Advanced Research Fellow in #Informatics to join UK DRI at Imperial Lead a programme integrating biological data across the multiple "omes" for the UK DRI Multi-‘omics Atlas Project (MAP-AD) 🗓️ 17 May 👉 bit.ly/2SzbS11 ♻️Pls RT!
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We're thrilled to have you on board Jess! And so excited to start this project, it's going to be a lot of fun! 🧠🔬🎉
Jessica Griffiths@GriffithsJess9418 Feb 2021
I am delighted to announce that I will be starting a postdoc @UKDRI next month, joining the Multi-‘omics Atlas Project (map-ad.org) team! I will be working with the incredible @jojacksonhere and Prof Paul Matthews @ImperialBrains and Prof Seth Grant @EdinburghUni ...
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I am delighted to announce that I will be starting a postdoc @UKDRI next month, joining the Multi-‘omics Atlas Project (map-ad.org) team! I will be working with the incredible @jojacksonhere and Prof Paul Matthews @ImperialBrains and Prof Seth Grant @EdinburghUni ...
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… characterising the synaptomic changes in human AD🧠 The first half of this journey will be kicking off @EdinburghUni and the second half @ImperialBrains. Can’t wait to get started in Edinburgh!🏴󠁧󠁢󠁳󠁣󠁴󠁿
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Jessica Griffiths retweeted
Robert Beattie@BeattieScience6 Sep 2020
I’m amazed we live in a world where I can download and #3Dprint a lab grade slide scanning microscope in my home. The @OpenFlexure #microscope is an #OpenSource project from @UniofBath that has been adapted for field research, #STEM #education, and #outreach. @ISTAustria
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Jessica Griffiths retweeted
Jonathan Schott@jmschott2 Sep 2020
It has never been more vital for the government to honour its commitment to increase funding for dementia research — coverage @thetimes including a letter from @AlzResearchUK @alzheimerssoc and UK researchers @ProfJTOBrien @TSpiresJones @skohlhaas @FiCarragher
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Dedicating my first tweet to the very first preprint from the Martínez-Garay Lab! Proud to be a part of this paper and to have worked in this wonderful group for my PhD. Happy Friday everyone! ☺️
bioRxiv Neuroscience@biorxiv_neursci28 Aug 2020
Cellular and behavioral characterization of Pcdh19 mutant mice: subtle molecular changes, increased exploratory behavior and an ... biorxiv.org/cgi/content/shor… #biorxiv_neursci
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