@GuanLab

mTOR - HIPPO - Autophagy

Joined April 2014
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2Media
Hippo pathway in development and cancer ow.ly/JjhRS @TrendsMolecMed, a review by Guan @UCSanDiego.
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The importance of mentoring undergrads sciencemag.org/content/347/6…
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Great pub, @GuanLab RT Distinct mechanisms sense amino acids leucine and glutamine at the lysosome bit.ly/1AAQyqS #mTOCR1
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New article on the latest findings regarding the functions of YAP/TAZ beyond the Hippo pathway nature.com/nrc/journal/vaop/…
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Distinct mechanisms sense amino acids leucine and glutamine at the lysosome bit.ly/1AAQyqS #mTOCR1
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2 paper out online today: GNAQ/GNA11 mutations in Uveal Melanoma promote tumorigenesis by activating YAP ow.ly/xph8x
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1 paper by Guan, Zhang & co @UCSDHealth uses genetic & pharmacologic means to show that mutant Gq/11 activates YAP ow.ly/xpheO
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Mischel & co put "mTORC2 in the center of cancer metabolic reprogramming" in a Review @Trends_Endo_Met ow.ly/xcrti
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