A microbial ecologist with over thirty years of experience on gut ecology. Nutrition, Microbiome and Health; Reference-free and Guild-based Microbiome Analysis.
Joined July 2015
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A core microbiome signature as an indicator of health sciencedirect.com/science/ar…
Your gut microbiome is a seesaw for health! 🦠 Fiber-rich diets tip it toward Foundation Guild dominance, promoting weight control and metabolic health. Junk food fuels Pathobionts, driving obesity. #TCGScience #GutHealth
The Two Competing Guilds (TCG) Model of Core Microbiome
🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology.
🔗 Watch the full interview: oaepublish.com/interviews/mr… #GutHealth #Obesity #MRR #HostMicrobe
Liping Zhao retweeted
🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology.
🔗 Watch the full interview: oaepublish.com/interviews/mr… #GutHealth #Obesity #MRR #HostMicrobe
Taxa should no longer be used as entry point analytical units for microbiome datasets. Genomes should be.
Liping Zhao retweeted
🎉Huge congratulations to our Editor-in-Chief, Dr. Jizhong Zhou, on being elected to the National Academy of Sciences! This prestigious honor recognizes his outstanding contributions to Microbial Ecology. We are proud and thrilled!
@theNASciences nasonline.org/news/2025-nas-…
Liping Zhao retweeted
Researchers, including CIFAR's @Gutzhao, have developed a new method to identify crucial gut microbes essential for health. 🦠
This discovery could lead to precision nutrition and personalized therapies for managing diabetes, IBD and more.
medicalxpress.com/news/2024-…
Liping Zhao retweeted
Immensely grateful to all experts who contributed this piece with their expertise and efforts! @nsegata @cibiocm @GiovanniCammar9 @h_sokol @fasnicar @Siew_C_Ng @Gutzhao @PaedsRH @RaesLab @HoldGeorgina @ChristianHvas @KorenLab @TheTunLab @MireiaVallesc @mcarmen_collado @epasolli
Meet Evo, the DNA-trained AI that creates genomes from scratch | Science | AAAS science.org/content/article/…
The third pillar of guild-based microbiome data analysis is interaction focused perspective. Co-abundance network analysis of high quality MAGs is used to identify potential guilds jci.org/articles/view/185395
The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. jci.org/articles/view/185395
The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. jci.org/articles/view/185395
Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. jci.org/articles/view/185395
Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. jci.org/articles/view/185395
What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! cell.com/cell/fulltext/S0092…
What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! cell.com/cell/fulltext/S0092…
Liping Zhao retweeted
🚨New Paper Alert🚨
Our new #microbiome research, co-led with @LiatShenhav, published today in @CellCellPress!
We show that #breastfeeding "paces" gut & nasal microbiome development to prevent #asthma in the @CHILDSTUDY.
#Tweetorial 🧵
cell.com/cell/fulltext/S0092…
This concept of stability of relationships as a marker of functional significance is central to understanding the microbiome as a complex adaptive system, where the resilience of microbial networks is directly linked to host health. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…
In essence, stability within guilds like FG and PG reflects an evolutionary adaptation, enabling the microbiome to sustain functions under environmental pressures that a less connected population could not. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…
Restoring and maintaining the TCG structure in the gut microbiome is therefore essential for it to function as a dynamic regulatory interface between the host and the environment. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…
It illustrates how dietary choices shift the balance toward either health or dysfunction, suggesting that restoring FG dominance through fiber-rich diets could recalibrate this balance, realigning it with the microbiome’s evolutionary purpose. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…
Thus, the stable competition between FG and PG is fundamental to the microbiome’s role as an adaptive nutrient sensor. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…
This imbalance exemplifies how the FG-PG competition, although adaptive, becomes maladaptive in today’s dietary landscape, where one guild is consistently favored. cell.com/cell/fulltext/S0092…
Are we ready to define a core microbiome signature as an indicator of health?
.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:
sciencedirect.com/science/ar…