@HayleyFrancies
 Cambridge, England
Joined July 2011
  • Tweets476
  • Following662
  • Followers437
4Media
Hayley Francies retweeted
Matthias Lutolf@TheLutolfLab13 Jun 2024
Imagine growing a miniature version of the human intestine in the lab to study gut biology in great detail and test medicines before clinical trials? We are happy to share our latest publication on bioengineered human mini-intestines: authors.elsevier.com/sd/arti… Let’s dive in!
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Hayley Francies retweeted
Open Targets@OpenTargets30 May 2024
What is the impact of modifying genes and proteins? 🧬 We're developing the #opensource Perturbation Catalogue to answer this, integrating harmonised and curated gene, variant, and expression data Are you a postdoc or full stack dev? Help us build this!
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Hayley Francies retweeted
Ben Lehner@BenLehner30 Apr 2024
Introducing the Domainome... Site saturation mutagenesis of 500 human protein domains reveals the contribution of protein destabilization to genetic disease by @ToniBeltran13 @CRGenomica @sangerinstitute @BGI_Genomics biorxiv.org/content/10.1101/…

Site saturation mutagenesis of 500 human protein domains reveals the contribution of protein...

Missense variants that change the amino acid sequences of proteins cause one third of human genetic diseases[1][1]. Tens of millions of missense variants exist in the current human population, with...

biorxiv.org
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Your weekly reminder that there is an amazing dual CRISPR perturbation dataset waiting for your excellent skills and enthusiasm! Join us! Deadline April 24th embl.org/jobs/position/EBI02…
Evangelia Petsalaki@e_petsalaki27 Mar 2024
Amazing #postdoc position alert in our group @emblebi! Funded by @OpenTargets , collaboration with the @Garnettlab @sangerinstitute and industry partners. We have produced the largest dataset to date of dual CRISPR perturbations (65K pairs, 45 cell lines, 2 tissue types) and are
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Hayley Francies retweeted
Fiona@fiona_fb311 Mar 2024
Another huuuuge dataset out of the @Garnettlab! Great work team. Very valuable resource for the community 😃 aacrjournals.org/cancerdisco…
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Hayley Francies retweeted
Simon Buczacki@SiBucz7 Mar 2024
New post-doctoral scientist position in our group. @OpenTargets funded project in collaboration with Sanger and BRIC (🇩🇰). Multiomic analysis of response to chemoradiotherapy in rectal cancer. jobs.ac.uk/job/DGK366/post-d…
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Hayley Francies retweeted
Garnett Lab@Garnettlab10 Oct 2023
Are you a wet-lab or computational scientist working on #cancer? Then the Cell Model Passports (CMP) from the @DepMapSanger @sangerinstitute is a resource you need to know about. cellmodelpassports.sanger.ac…
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Hayley Francies retweeted
Chris Tape@christophertape19 Sep 2023
We are recruiting for multiple positions @uclcancer — please share! 1. Postdoc We're looking for a creative and passionate postdoctoral fellow to study single-cell drug responses using autologous patient-derived microenvironment organoids. ucl.ac.uk/work-at-ucl/search…
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How is the current version different from the preprint, summarised in the following link? xitter.cf/isidrolauscher/status/…
Isidro Cortes-Ciriano@isidrolauscher24 Nov 2022
We are most happy to present SComatic, an algorithm for de novo detection of somatic mutations in high-throughput single-cell data, including single-cell RNAseq and ATAC-seq. Monumental effort led by @fran_muyas biorxiv.org/content/10.1101/… Thread 👇
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Hayley Francies retweeted
Matthias Lutolf@TheLutolfLab3 Jul 2023
We have several vacancies for junior group leaders @IHB_Research! Join us and conduct groundbreaking research in a unique institute that seamlessly integrates academic and pharmaceutical research in the vibrant city of Basel. Please RT if you know someone who should apply!
Institute of Human Biology@IHB_Research3 Jul 2023
We’re seeking Early Career Scientists to establish their own independent #research program, with competitive funding, across three key focal areas. Open to mature #scientists with PhD or Postdoctoral training in #HumanModelSystems. Apply to #TeamIHB here: bit.ly/3NyRjul
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Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens biorxiv.org/cgi/content/shor… #biorxiv_genomic
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Leaving @OpenTargets @sangerinstitute in June after 6 incredible years! Proud to have been part of OT & to have helped build OT Genetics. Looking for a passionate scientist to lead the multi-disciplinary genetics team & working at the interface of academia and industry.
Open Targets@OpenTargets4 May 2023
Lead our Genetic Analysis team! Drive the scientific development of OT Genetics: ➡️systematically aggregate and analyse the world’s genetic association data to better understand disease biology ➡️integrate data to link genes and diseases Apply by 31 May sanger.wd3.myworkdayjobs.com…
Graphic reads: Join the team! It features the Open Targets logo as well as pairs of cartoon characters working together or high-fiving.

ALT Graphic reads: Join the team! It features the Open Targets logo as well as pairs of cartoon characters working together or high-fiving.

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A few days left to apply! #postdoc position focused on decoding cancer genome complexity using #long-read sequencing methods - Details 👇 @nanopore @PacBio @emblebi
Isidro Cortes-Ciriano@isidrolauscher10 Mar 2023
Replying to @isidrolauscher
Please DM me for further info. Full details about the position and how to apply below. **RT and word of mouth most appreciated!** @embl @CR_UK embl.org/jobs/position/EBI02…
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Hayley Francies retweeted
Jesse Boehm@boehmjesse18 Apr 2023
Highly recommended! Learn about the Human Cancer Models Initiative (HCMI) at 2:30pm (NOW) in room W314A! This is the future of cancer models. Over 275 organoids from the network now available from @officialatcc, 500 more coming with releases monthly! #AACR23 #AACR2023
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A super awesome lab doing some pretty cool science! These positions are most definitely worth a look!
Garnett Lab@Garnettlab2 Apr 2023
Two funded #postdoc positions available to lead cool areas of research in the team. Details in the thread and see @Sangercareers website. The @sangerinstitute has an amazing PDF programme helping PDFs to deliver leading-edge research and prepare for future leadership roles.
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Join us for this exciting meeting ! Looking forward to all the great talks and discussions.
Human Technopole@humantechnopole14 Mar 2023
📢 Calling all scientists! Join us for the 1st European Cancer Dependency Map Symposium #EUDepMap with top researchers from @Humantechnopole @emblebi @sangerinstitute @ETH_en on cutting-edge research on cancer vulnerabilities and therapeutic targets. bit.ly/3TdGLU3
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We are recruiting! Exciting #postdoc position in my team to train on truly large-scale long-read data analysis (@nanopore @PacBio) in the context of #cancer (tumour profiling and liquid biopsy analysis)👇
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Hayley Francies retweeted
RabP@1RabP6 Mar 2023
The simply awesome @LouisePrinjha of course. The most inspiring woman and future author I know.
Bookaholic Bex@BexBookaholic6 Mar 2023
To celebrate #InternationalWomensDay I want you to nominate an inspiring woman to win a book of their choice up to £20 in value. To enter: ▪︎ follow me ▪︎ retweet this ▪︎ tag below your nominee UK only. Winner picked 12/3/23 at midnight. #BookTwitter #bookgiveaway
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It's always a bit exciting when the Tape lab drop a paper. This one is no exception! Congratulations @christophertape and team!
Chris Tape@christophertape16 Feb 2023
Very excited to share our new pre-print: ‘A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation’ led by @QinXiao1990 and @FerranC96. (1/11) biorxiv.org/content/10.1101/…
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Huge congratulations to Prof Matt Hurles (@mehurles ) who has been appointed as the new Director of @sangerinstitute! 🎊 Currently Head of the Human Genetics Programme, Matt will formally take up the Directorship later this year. Find out more⤵️ bit.ly/3Xq3T26
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