Official SoMe account of The International Journal of Surgical Pathology. Editor in Chief @Williamson_SR | Social Media Editor @MirunaPopescu13.
Joined September 2021
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📢IJSP will be significantly reducing acceptance of case reports.
💡To be considered, a case report must:
➡️focus on histopathology
➡️present new morphologies / new or unusual IHC results / novel molecular findings
Looking forward to your submission!
#PathTwitter
@Williamson_SR
Histologic features favoring CMV hepatitis in liver allograft biopsies with overlapping rejection-type injury
➡️Microgranulomas
➡️Neutrophilic microabscesses
Difficult topic, covered by IJSP. Read more here 👉🏼 tinyurl.com/5enfmwv3
#PathTwitter #GIPath #MedicalLiverPath
Do you report extranodal extension (ENE) in colorectal carcinoma?
This study in IJSP says you should! ENE is associated with increased nodal tumor burden & independently predicts shorter disease-free survival in CRC.
Check it out -> tinyurl.com/3dvphak6
#PathTwitter #GIPath
🤖 Made with AI
Int J Surg Pathol retweeted
#GUPath read of the day in IJSP ➡️ Expanding the histologic spectrum of TFEB-amplified RCC to include rhabdoid features, among others.
Check it out 👉🏼 tinyurl.com/ykpvuyrt
#PathTwitter #PathX
#Hemepath meets #Breastpath meets #BSTpath
Sclerosing extramedullary hematopoietic tumor (SEMHT) presenting in the breast. SEMHT is a rare manifestation of MPNs. The main dx clue are the atypical megakaryocytes (CD61+).
Read more in IJSP -> tinyurl.com/bdj7nhpv
#PathTwitter
#GUPath read of the day in IJSP ➡️ Expanding the histologic spectrum of TFEB-amplified RCC to include rhabdoid features, among others.
Check it out 👉🏼 tinyurl.com/ykpvuyrt
#PathTwitter #PathX
🤖 Made with AI
Int J Surg Pathol retweeted
Primary breast anaplastic large cell lymphoma is typically associated with the presence of an implant...
✅Correct, but...
🚨☝️🏼It may also rarely occur in the absence of an implant
Read the IJSP case report 📜of the day: tinyurl.com/437tjpa6
#Hemepath #breastpath #PathTwitter
Int J Surg Pathol retweeted
The many faces of a rare but important to recognize entity -- SMARCA4-deficient carcinomas of the stomach/GEJ
🚨Awareness of existence & appropriate IHC are 🔑
Shao-Jie Sheng et al. in IJSP -- clinicopathologic features of these tumors tinyurl.com/57cm6zj3
#GIPath #PathTwitter
Int J Surg Pathol retweeted
Who knew a simple histochemical stain could tell you so much about patterns of growth in non-mucinous adenocarcinoma? 😮
In this IJSP paper📜 tinyurl.com/3b8w5zsx, Zhou et al. show us how patterns of elastin stain help us in the DDx AIS vs. MIA vs. IA.
#PulmPath #PathTwitter
Int J Surg Pathol retweeted
Who finds subtyping vascular anomalies difficult 🔬?
In this Research Article in IJSP, Barwad et al. take an in-depth look at FAVA (Fibro-Adipose Vascular Anomaly) and its differentials 👉🏼tinyurl.com/4mvjx2z5
A worthwile read📜 in non-neoplastic #BSTPath
#PathTwitter #PathX
Int J Surg Pathol retweeted
🚨Neuroendocrine marker expression in mucosal melanomas of the H&N might represent an important diagnostic pitfall!
Shah et al. in IJSP (link: tinyurl.com/4227ejhn) show how synaptophysin alone might not be the best screening marker in the dx work-up.
#PathTwitter #ENTPath
ALT Synaptophysin.
Int J Surg Pathol retweeted
Lung mass, 79F, CK7+/CK20-/TTF1+/Napsin A+ -> primary lung adenoCA, right?
Well...the dangers of relying only on #IHCPath!
Check out this illustrative paper in IJSP (link: tinyurl.com/4a7taexa) by Alfonso-Rosa et al. describing an important pitfall!
#PathTwitter #Lungpath
Int J Surg Pathol retweeted
Adrenal cortical carcinoma arising from adrenal rests in ectopic locations --> read about this rare phenomenon in this Open Access IJSP Case Report by Alperen Onur İşler et al.👉🏼 tinyurl.com/5yrps9st
#PathTwitter #EndocrinePath #PathX
Int J Surg Pathol retweeted
There's still a LOT to learn about renal low-grade oncocytic tumors
IJSP read of the day: "Low-Grade Oncocytic Tumor (LOT): Clinicopathological, Morphological, Immunohistochemical and Cytogenetic Study of 17 Tumors" (Gutiérrez et al.): tinyurl.com/56z6w32f
#GUPath #PathTwitter
Int J Surg Pathol retweeted
Diffuse and strong INSM1+++ in sinonasal lymphoepithelial carcinoma😮 Morphology + EBV-ISH save the day.
🚨Important pitfall to be aware of --> Read this IJSP Case Report by Elsafy et al. tinyurl.com/bdfapyxb to learn more about this!
#PathTwitter #ENTPath
Int J Surg Pathol retweeted
Rare tumors find their way to IJSP --> what does #PathTwitter think about this primary uterine tumor in an older F👵🏼?
Here's a hint: desmin+++
Check out this Case Report by Ahmed et al. and see if you got it right! Link: tinyurl.com/5f7ndy6d
#PathX #gynpath #bstpath
Int J Surg Pathol retweeted
🚨📜🔬IJSP interesting case report of the day -->
EWSR1::FEV-rearranged prostatic Ewing sarcoma mimicking high-grade neuroendocrine carcinoma, showing AR and focal NKX3.1 positivity (link: tinyurl.com/yp2xkhzs)
Pathology is indeed challenging!
#PathTwitter #GUPath #BSTPath
Int J Surg Pathol retweeted
🚨Not all MDM2 amplified malignancies are well differentiated/dedifferentiated liposarcomas.
Read this IJSP paper 📜describing 3 cases of extrauterine müllerian adenosarcomas with sarcomatous overgrowth and MDM2 amplification
👉🏻tinyurl.com/yh4x5ppp
#PathTwitter #Gynpath
Int J Surg Pathol retweeted
IJSP reports SS18-SSX antibody is indeed highly specific for synovial sarcoma, as this study by Hariri et al. performed on 100 carcinomas & 5 melanomas shows.
Next generation #IHCPath is truly a helpful ancillary tool.
Read more here: tinyurl.com/539btrch
#PathTwitter #BSTPath
Int J Surg Pathol retweeted
Round cell sarcomas are a difficult area of #BSTPath IJSP comes to help🚨
In this excellent paper, Rekhi et al. present the clinicopathological features of 12 BCOR::CCNB3 sarcomas & beautifully review the existing literature.
Check it out here tinyurl.com/76ydyzaa
#PathTwitter
Int J Surg Pathol retweeted
PanCK is indeed consistently expressed in the majority of epithelial tumors, as this open access IJSP paper by Menz et al. shows (👉🏻tinyurl.com/2k53zxu4), but remember:
🚨PanCK can be negative in a subset of
➡️RCCs
➡️Adrenocortical Ca
➡️Neuroendocrine neoplasms
#PathTwitter
