@IMMUNOLAB

Immunologist studying the intersection of inflammation, host-microbe interactions, translational biology and cancer.

 Virginia Tech
vetmed.vt.edu/people/bios/allen-irving.asp
Joined June 2015
  • Tweets1.4K
  • Following1.9K
  • Followers1.7K
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Congratulations to @VTCeZAP affiliated faculty @IMMUNOLAB on receiving a 2.6 million award from The National Institutes of Health to investigate #pancreaticcancer. 👏 bit.ly/44beTUh
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Irving Coy Allen retweeted
Daniel J. Slade@TheSladeLab25 Jan 2023
The entire Jutras lab is always doing big things. Nice work!
VT Biochemistry@vtbiochem24 Jan 2023
The U.S. @HHSGov and @cohengive announced 10 Phase 1 winners in the @Lyme_X Diagnostics Prize (a competition to accelerate the development of #LymeDisease diagnostics and Brandon Jutras (@jutraslab) was one of the winners! Awesome work! Read more here 👇 lymexdiagnosticsprize.com/an…
A faculty member speaks in front of a small crowd in a laboratory.

ALT A faculty member speaks in front of a small crowd in a laboratory.

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Excited to share our latest study published in @MolPsychiatry linking SARS-CoV-2 to inflammasome activation in brain microglia (doi.org/10.1038/s41380-022-0…). Could COVID-19 be a future risk factor for neurodegenerative diseases like Parkinson’s? Our ongoing research aims to find out.

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Molecular Psychiatry - SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

nature.com
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Irving Coy Allen retweeted
John Lukens@LukensJohnR1 Mar 2022
Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury congrats to 2 of my favorite Hokies 🦃@IMMUNOLAB @LabTheus. frontiersin.org/article/10.3…
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Irving Coy Allen retweeted
Alicia Pickrell@PickrellLab25 Feb 2022
Congratulations @laurenfritsch96! Please check out our collaborative work with @immunolab and @LabTheus. Thank you for the joint effort of everyone involved:) Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury frontiersin.org/article/10.3…
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My heart is definitely singing with joy today 💕I couldn’t have asked for a better day communicating sci with some other stellar female scientists (@HannahIvester) and inspiring children that their future in science is as big as they dream. I even won 1st place 🥇 @IMMUNOLAB
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Irving Coy Allen retweeted
The Manresa lab@mario_manresa13 Dec 2021
I am thrilled to share my latest research article in eosinophilic esophagitis published in Mucosal Immunology. This is a follow-up from our previous publication in Gastroenterology. Description in the thread below and all info on the attached link. rdcu.be/cC8M7
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This is pretty freaking awesome - mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent science.org/doi/10.1126/scit…

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

An Ixodes scapularis saliva mRNA vaccine induces tick resistance and prevents Borrelia burgdorferi infection in guinea pigs.

science.org
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Awesome Work - Self-guarding of MORC3 enables virulence factor-triggered immunity | Nature nature.com/articles/s41586-0…
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Irving Coy Allen retweeted
Martin Picard
@MitoPsychoBio25 Oct 2021
The importance of stupidity in scientific research. Great piece especially for graduate students and trainees. cob.silverchair-cdn.com/cob/…
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Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated etiology of autoimmune risk loci science.org/doi/10.1126/scii…

Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated...

Single-cell ATAC sequencing maps the cell type–specific regulatory potential of transcription factors and autoimmune disease risk loci.

science.org
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Irving Coy Allen retweeted
Dr. Kim O’Sullivan@Kim_M_OS11 Oct 2021
Awesome guest speaker for this weeks @MonashCID seminar-we have Prof. Kate Schroder presenting on all things inflammasome. Join us tomorrow at 12pm Melbourne time. Non-CID members can DM for zoom link! @inflammasomelab @SCSMonash @Monash_FMNHS @CiiiD_Hudson
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Early exposure to house dust mite can induce tolerance and prevent allergic asthma, but requires H202 to regulate dendritic cells. Read more from Huijuan Yuan @yuan_huijuan, Anuradha Ray and colleagues at the University of Pittsburgh @PACCM nature.com/articles/s41385-0… #mitochondria
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Attention Everyone!! The Journal of Leukocyte Biology is seeking the next great Editor in Chief. The Journal requires a visionary leader and advocate to advance the publication and to ensure its relevance for years to come. For more information visit us bit.ly/3AWttRH
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Don't forget Inflammazoom is returning on Monday at 9am GMT with a great line up of speakers: Si Ming Man and @_kaiwenchen.........
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RIP to gut homeostasis? Loss of #RIPK1 in dendritic cells increases spontaneous colonic inflammation which in turn limits DSS colitis: nature.com/articles/s41385-0… #OpenAccess #IBD
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In this fantastic pair of papers, @JRiveraNievesL1 and colleagues, demonstrate the importance of homing and localization of plasma cells in the murine intestinal lamina propria for luminal IgA delivery. #FridayReads #OpenAccess
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Cells of the human intestinal tract mapped across space and time | Nature nature.com/articles/s41586-0…
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Brown adipose tissue monocytes support tissue expansion | Nature Communications nature.com/articles/s41467-0…

Brown adipose tissue monocytes support tissue expansion

Nature Communications - Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose...

nature.com
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