@InnoglyA

Innovation with Glycans: New Frontiers from Synthesis to New Biological Targets (ex COST action)

innogly.eu/
Joined April 2019
  • Tweets2.7K
  • Following1.2K
  • Followers1K
30Media
On the importance of dissemination and communication is Science. Glycans and Glycosciences: an intro for everyone innogly.eu/glycans-and-glyco… #glycotime
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FAM20B phosphorylates Xyl of the matriglycan primer disaccharide and dystroglycan has an unexpected xylose phosphatase function involved in regulating matriglycan extension. #glycotime science.org/doi/10.1126/scie…

Xylose phosphatase activity of dystroglycan self-regulates its receptor function

Dystroglycan (DG) is an extracellular matrix receptor crucial for tissue development and pathogen entry. DG harbors a long, complex glycan called matriglycan. Loss of matriglycan or reduction in its...

science.org
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INNOGLY COST Action retweeted
Nature Rev Immunol@NatRevImmunolMay 2
Freedom of scientific inquiry: reclaiming space for controversy dlvr.it/TSKgk2

Freedom of scientific inquiry: reclaiming space for controversy

Nature Reviews Immunology - No matter how small the possibility, or how inconvenient the topic, scientists must maintain the humility to acknowledge that we could be wrong. Our inability to remain...

nature.com
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Ticks and sugars #glycotime Alpha-Gal: The Sugar Humans Lost, and the Allergy That Found Us entomologytoday.org/2026/04/…

Alpha-Gal: The Sugar Humans Lost, and the Allergy That Found Us

A new review details the current state of scientific knowledge on alpha-gal syndrome, a severe allergy to red meat and other products containing alpha-gal sugars.

entomologytoday.org
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New online! Reverse vaccinology 3.0 dlvr.it/TRR35t
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Jonathan Kagan@jkagan1Mar 12
Want to know how cancer vaccines can keep you alive? Very pleased to join several luminaries in the field to offer a comprehensive review on this important topic. @harvardmed @BostonChildrens #cancer #vaccine nature.com/articles/s41591-0…

Clinical development of cancer vaccines

Nature Medicine - This Review highlights insights from recent clinical trials and discusses critical factors for optimizing cancer vaccines, with a focus on proxies for vaccine efficacy, neoantigen...

nature.com
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INNOGLY COST Action retweeted
Prof. Akiko Iwasaki
@VirusesImmunityFeb 16
Very proud of @Kwon_Dongil, @sachinbhag, and Stephen Ehrenzeller for putting together a new review - "Harnessing mucosal immunity for protective vaccines" published today @NatRevImmunol! Please use the link below to access this review 📖 rdcu.be/e4eEU
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Nature Rev Immunol@NatRevImmunolFeb 16
Harnessing mucosal immunity for protective vaccines dlvr.it/TQzxPG

Harnessing mucosal immunity for protective vaccines

Nature Reviews Immunology - Many clinically relevant pathogens enter the body through mucosal surfaces, yet conventional parenteral immunization is insufficient to elicit robust mucosal immunity....

nature.com
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Samuel Hume
@DrSamuelBHumeJan 4
5 clinical trials to watch in 2026 Ras inhibition in pancreatic cancer, new approaches for prevention of heart disease, Retatrutide vs. Tirzepatide for obesity, and a next-generation antibody in Alzheimer's disease Read it here: breakingground.substack.com/…
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Samuel Hume
@DrSamuelBHume21 Dec 2025
10 breakthroughs in medicine in 2025 Read it here: breakingground.substack.com/…
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Eric Topol
@EricTopol19 Dec 2025
Discovery of a new checkpoint of cancer cells, a pathway to block and enhance immunotherapy cell.com/cell-reports/fullte…
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Denis Wirtz@deniswirtz14 Dec 2025
Download our large database of funding opportunities for early-career faculty and researchers Download it here: research.jhu.edu/rdt/funding… 433 funding opportunities.
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Tony@MolinaroTony27 Nov 2025
great paper from the neapolitan Crew!!! Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide @di_flaviana @AlbaSilipo @FabrizioChiodo onlinelibrary.wiley.com/doi/…

Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopo...

The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by...

onlinelibrary.wiley.com
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INNOGLY COST Action retweeted
Tony@MolinaroTony27 Nov 2025
great paper stunning structures and biology @AlbaSilipo @di_flaviana Chemical Synthesis of Arabinogalactans from the Mycobacterium tuberculosis Cell Wall up to the 92‐mer and Structure–Conformation–Activity Relationship Studies onlinelibrary.wiley.com/doi/…

Chemical Synthesis of Arabinogalactans from the Mycobacterium tuberculosis Cell Wall up to the...

An arabinogalactan 92-mer from the Mycobacterium tuberculosis cell wall has been synthesized through an orthogonal one-pot glycosylation strategy based on glycosyl ortho-(1-phenylvinyl)benzoates,...

onlinelibrary.wiley.com
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Marcin Czerwinski@CzerwinsMarcin29 Nov 2025
Protein glycosylation: an emerging regulator of allergic diseases tinyurl.com/bdw7j958 #gtlycotime
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Dr. Catharine Young
@DrCatharineY17 Oct 2025
Just in case any one is wondering: Biomedical scientists spend an average of 12 years in training before reaching an independent position. That is more than most medical residences.
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Vijay Rathinam@RathinamVA18 Oct 2025
Sugar coats shield immunogenic RNA modification: A new function for RNA glycosylation: Molecular Cell cell.com/molecular-cell/full… @VinnieViruses
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Michael 英泉 Eisen
@mbeisen15 Oct 2025
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com/
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Jonathan Kagan@jkagan126 Sep 2025
meta-PAMPs: A new class of immunostimulatory molecules that control the ability of bacterial factors to operate as PAMPs. Jordan Jastrab reveals that wall teichoic acid (WTA) is a key regulator of inflammasomes and interferons during infection. biorxiv.org/content/10.1101/…

Wall teichoic acid is required for DNA-triggered innate immune receptor activation by Staphylococ...

Receptors that stimulate inflammation are commonly activated by ligands that are buried within microbial cells. The mechanisms that facilitate immunostimulatory ligand release from microbes during...

biorxiv.org
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Prof. Nikolai Slavov
@slavov_n25 Sep 2025
bioRxiv has a dedicated section for negative results. Use it. Share negative results. Your colleagues will appreciate it.
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Nature Rev Immunol@NatRevImmunol22 Sep 2025
Lessons from neoadjuvant immunotherapy in melanoma: understanding antitumour immunity and tumour escape bit.ly/3KbHowV
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