🎧 Behind the Breakthroughs Step into the minds shaping the future of medicine. Listen on your preferred platform: Apple → hubs.li/Q03CQZRK0 Spotify → hubs.li/Q03CQYNy0 IPM → hubs.li/Q03CQYph0 #PrecisionMedicine #BehindTheBreakthroughs #MedTech #Biotech

Hussam Al Kateb: Inside Mayo Clinic’s Molecular Diagnostic Revolution The Clinical Genomics Lab co-director discusses whole transcriptomics-based gene fusion diagnostics and evolving #cancergenomics innovation @mayocliniclabs #moleculardiagnostics hubs.li/Q04BTRRz0

Targeted Brain Ultrasound Could Help Relieve Schizophrenia Symptoms Low-intensity targeted #ultrasound could be an effective treatment for delusions in people with #schizophrenia or schizoaffective disorder @ShohamLab @nyugrossman #Alzheimersdisease hubs.li/Q04BTPdT0

New Molecular Target for Treating Type 2 Diabetes Identified Targeting the mitochondrial protein Miro1 could offer a new approach to treating insulin resistance in type 2 diabetes @LSU @NIH @BrownUniversity #diabetes #insulinresistance #mitochondria hubs.li/Q04BTL6K0

IMU Biosciences and UK Biobank to Create Large Immune Dataset The U.K. biotech IMU Biosciences will help create a large and detailed immune dataset for 80,000 people in the @uk_biobank @WatersCorp @UltimaGenomics #biobanks #immunecells #omics hubs.li/Q04BLGK30

Early Drivers of Autoimmune Kidney Damage Identified, Opening Door to Targeted Treatment New research reveals how autoimmune kidney inflammation develops and identifies an antibody-based strategy that may prevent lasting damage @UOsaka_en #genetics #omics hubs.li/Q04BLF420

GLP-1 Drugs Linked to Fewer Heart Complications and Infections After Surgery GLP-1 medications may reduce complications after surgery, with new research linking their use to fewer cardiovascular events and infections @UTHealthHouston #diabetes #GLP1 hubs.li/Q04BxXXY0

Breast Cancer Treatment Response Predictors Revealed Through Multi-Omics Analysis Researchers use #multiomics and spatial profiling to identify potential #biomarkers of treatment response and resistance in breast cancer @FudanUniversity #breastcancer hubs.li/Q04BxWdx0

Magnetic Millirobots Could Deliver Cancer Drugs Directly to Hard-to-Reach Tumors A modular robotic system uses magnetic guidance to deliver drugs precisely, with potential applications in oncology @JohnsHopkins #anticancerdrugs #AI #drugdelivery hubs.li/Q04BcbgM0

Single-Cell Profiling Exposes Hidden Diversity Within Pancreatic Tumors Clonal diversity in #pancreaticcancer cells reveals potential biomarkers and targets linked to aggressiveness and immune evasion @DespinaKalf @nyugrossman #transcriptomics #scRNAseq hubs.li/Q04Bc8F40

Advanced Omics Reveal 'Poor Outcome' Marker for Neuroblastoma A gene signature for those mesenchymal cells that make #neuroblastoma resistant to standard therapy has been revealed @DrAnandPatel14 @mikedyerlab @StJudeResearch #omics #genesignature hubs.li/Q04Bc7DV0

Trapping ecDNA in Micronuclei Improves Cancer Patient Survival Trapping extrachromosomal (ec)DNA in micronuclei during cell division weakens aggressive cancers with high levels of ecDNA in their cells @anton_gh @ChariteBerlin #DNAdamage #cancertherapy hubs.li/Q04Bc66W0

Whole-Genome Diagnostics Evolve with RNA and Pangenome Integration @AmbryGenetics' GenomeNext test uncovers rare diseases with more comprehensive sequencing, diverse genomic references, and ongoing reanalysis #genetictesting #WGS #DNA #rarediseases hubs.li/Q04BpK790

ADPKD Gene Therapy Development at Newly Launched Estuary Biotherapeutics As one of the world’s most common genetic diseases, developing treatments for ADPKD is both a daunting and important task #EstuaryBiotherapeutics #genetherapy #kidneydiseases #ADPKD hubs.li/Q04BpJZW0

Metabolomic Aging Clock Predicts Chronic Disease, Mortality Risk Researchers identify 56 age-associated metabolites to develop aging clocks linked to long-term health outcomes @sjtu1896 #metabolomics #agerelateddiseases #aging #chronicdisease hubs.li/Q04BgqZ30

CRISPR-Based Test Improves Detection of HIV and Other RNA Viruses An engineered CRISPR Cas13a enzyme can detect RNA with 100 times greater sensitivity than its original version @RiceUniversity #CRISPR #HIV #diagnostictools hubs.li/Q04Bgn-c0

Childhood Cancer Linked with Abnormal Antibodies Children who develop cancer have an unusually high number of #autoantibodies that affect cellular machinery involved in DNA repair @UiB #antibodyresponse #pediatriconcology #DNArepair hubs.li/Q04B8nv_0

Mechanical Pressure Triggers Cancer Cell Death, Revealing Potential New Defense Against Metastasis Mechanical confinement does more than challenge migrating #cancercells. It may help determine which cells survive @CAS__Science #apoptosis #metastasis hubs.li/Q04B7__g0

Lung and Mouth Bacteria Linked to Long COVID Severity and Symptoms “What we don’t know is whether these changes came before a COVID infection...” said @ProfJDChalmers, chair of respiratory research at the University of Dundee. hubs.li/Q04zZsf60

NAD-Boosting Supplement Does Not Slow Parkinson’s Disease To test whether increasing NAD translated into meaningful clinical improvements, researchers led by @chtzoulis at the @UiB and @haukeland_no conducted the NOPARK trial. hubs.li/Q04zPFj20

Enzyme Biomarker May Predict CDK4/6 Inhibitor Resistance in Breast Cancer Nuclear localization of fumarylacetoacetate hydrolase is associated with CDK4/6 inhibitor resistance in hormone receptor positive #breastcancer @tarumurmur @KanarekNaama #biomarker hubs.li/Q04zDc7q0