Executive Director of the Molecular Cardiology Research Institute, Physician-Scientist, Eagles fan

Joined November 2018
Faculty, staff and trainees from our Molecular Cardiology Research Institute volunteered with Community Servings this week, helping prepare medically tailored meals for people living with heart failure, diabetes, kidney disease and other medical conditions. @irisjaffelab
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New from the @IrisJaffeLab! 🙌 Ponatinib, a potent anticancer therapy, activates #EndothelialCells and platelets, driving plaque inflammation and death from MI and stroke in mice, mirroring clinical cardiotoxicities in patients with cancer. | @CircAHA 🔗 bit.ly/4mrUhAz
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Members of our Molecular Cardiology Research Institute volunteered with @communityserv yesterday to prep medically tailored meals for people with heart failure, diabetes, kidney disease and HIV. Proud to support patients beyond the lab. #TuftsMedicine @irisjaffelab
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Happening now at #AACR25 @TuftsMedicine + @TuftsMedSchool's @IrisJaffeLab presents Cardio-Oncology: A Novel Platform for Investigation. Room E353C 10:15am - 11:45am CST. #CancerResearchSavesLives #TuftsMedicine
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The talk describes a new mechanism discovered in @IrisJaffeLab showing how drugs that treat certain leukemias also cause heart attacks + strokes in cancer survivors. This research sets the stage for new treatments to protect leukemia survivors from CV side effects #AACR25
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The definition of bridging the #bench-to-bedside divide: Iris Jaffe is the inaugural director of the Tufts University–Tufts Medicine Research Enterprise #transformative @TuftsUniversity @TuftsMedicine @IrisJaffeLab ow.ly/hVF450VFGcq
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#TuftsMedicine’s @NavinKapur4 presents at #THT2025 on Safety and Efficacy of the preCARDIA System to Mechanically Reduce Cardiac Preload for Acutely Decompensated Heart Failure. 📍 Ensemble A-B | Level 2 ⏰ 7:55 – 9:12 am #Cardiology @IrisJaffeLab
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Fantastic talk from Alec Stepanian Tufts MD PhD student at AHA Vascular Discovery Conference in Chicago showing his innovative mechanism for arterial thrombosis in cancer patients treated with Ponatinib. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦⁦@MTChinMDPhD⁩ ⁦
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Congratulations to the outstanding team from the Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center. They are demonstrating national leadership in cardiovascular science innovation and discovery at an American Heart Association conference this week. #BCVS23
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Outstanding talk from Tufts MC researcher and collaborator ⁦@NavinKapur4⁩ on VA ECMO mitochondrial dysfunction and mitigation by cardiolipin targeting #bcvs23 ⁦@TuftsMCResearch⁩ ⁦@ChinLabTufts⁩ ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsGSBS⁩
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MCRI Jaffe Lab retweeted
Congratulations to Gayani Perera for presenting her work at AHA BCVS meeting that was also recently published, on snRNAseq in A mouse model of Barth Syndrome ⁦@TuftsMCResearch⁩ @tuftsgsbs ⁦@TuftsMedSchool⁩ ⁦@BarthSyndrome⁩ ⁦@samia_aali⁩ ⁦@rahul_8485⁩
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Congrats to @BeyerLab in organizing this outstanding meeting in basic & translational #CardioOnc! @APSPhysiology @IrisJaffeLab @FeixiongCheng @JuneWRhee @avirupguha @DrTochiOkwuosa @ICOSociety @Nazish_Sayed @GrumbachLab @pwburridge @yurikim_mdphd – at San Francisco, CA
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MCRI Jaffe Lab retweeted
Congratulations to our @crlsfalcons Winter 2022/2023 All-Scholastics and All League Student Athletes. Great job. @cambridge_cpsd @cambridgechron @CRLStweets
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MCRI Jaffe Lab retweeted
Good Luck Seniors on your final regular season game! @cambridge_cpsd @CRLStweets @cambridgechron
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MCRI Jaffe Lab retweeted
Congrats to Matt Scott @mscott336 (and a shout-out to Lauren Biwer @drlaurenbiwer) for winning the best poster awards at the Vascular Cell GRC! Representing the Orr lab well. Wish I could have been there to cheer!
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A new #review discusses the sex-specific role of mineralocorticoid receptor across #cardiovascular risks & diseases, including #obesity, pulmonary #hypertension, & #kidney diseases: ow.ly/mo8U50MupTg #SexDifferences @nicolelorrainew @IrisJaffeLab @TuftsMedicalCtr
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We are hiring! The DuPont Lab is seeking a postdoc to join our team to work on NHLBI-funded studies of sex differences in arterial stiffness! Please share and RT! Reach out to me directly if you are interested or have questions. #postdocjobs #postdocposition #bostonjobs – at Boston, MA
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Great talk by Mary Wallingford @WallingfordLab to a full house! @ivbm2022 @TuftsMedicalCtr @TuftsMCResearch @IrisJaffeLab
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