isb_bonn retweeted
Was great to contribute to this story together with @JanGerhartz @dpienkowska9 Ina Dressel & Thomas Geiger from the lab. #CRBN #Interactome #GLUES @CellChemBiol @EnamineGermany @iDikic2 @merckgroup @ibetportugal @MPIbp
Animation credit @proxidrugs
Paper: authors.elsevier.com/sd/arti…
isb_bonn retweeted
We found a #VHH antibody that allosterically inhibits sialic acid binding by the #TRAP transporter #SBP VcSiaP.
Thanks to the team @PhilippHendr @MartinPeter91 @sc_binder @PAKoenig @SMenzel @ @GavinHThomas @GHagelueken
Read the full story here:
doi.org/10.1038/s42003-024-0…
isb_bonn retweeted
Had to get one for the lab. #Falcon your falcon! Printed by @gha14
Instructions:
thingiverse.com/thing:273887…
isb_bonn retweeted
We are hiring! Looking for a #postdoc to join the team in the Nowak Lab to focus on chemical biology in cells and recombinant systems. Excited about protein degradation, small molecule proximity? get in touch!
#TPD #InducedProximity #ChemicalBiology
nowak-lab.com/
isb_bonn retweeted
It was a lot of fun to writhe the preview perspective article: “A Double Whammy for KEAP1”.
Discover the bivalent mechanism affecting KEAP1 and their implications for future small molecules.
#FirstPaperFromTheLab #Science #KEAP1 #Biology #NewPublication
sciencedirect.com/science/ar…
isb_bonn retweeted
We are #hiring! We have an open #postdoctoral position in my group with the focus on structural biology #cryoEM and X-ray crystallography of new #E3 ligases as well as #molecularglue complexes. @UniBonn @IsbBonn
nowak-lab.com/ Please RT!
isb_bonn retweeted
Great to have Dominika Pieńkowska and Ina Dressel join the Nowak lab! Dominika started her Master's project with us and Ina joined as a lab manager.
BelatedTwitter welcome Dominika and Ina! @JanGerhartz #GoTeam #TPD #NewPI @UniBonn @UniklinikBonn @IsbBonn
nowak-lab.com/
isb_bonn retweeted
Targeted protein #degradation: from mechanisms to #clinic. New molecular mechanisms can rapidly be translated - we can learn so much from nature.
Great to be able to share this piece with @jonathanMtsai Ben Ebert and Eric Fischer @fischerlab1. #TPD nature.com/articles/s41580-0…
isb_bonn retweeted
NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! nowak-lab.com
isb_bonn retweeted
Excited about #TPD and #InducedProximity? So are we, and we are recruiting! #postdoc #technician
#NowakLab #Germany @UniBonn @UniklinikBonn @ImmunoSens Please DM or reach us on nowak-lab.com/
isb_bonn retweeted
New in JBC press: "Scientists' results provide the basis for a rational improvement of SR-4835 towards Cdk12 inhibition and a gain in selectivity over other transcription regulating CDKs."
Learn more:
jbc.org/article/S0021-9258(2…
ALT Figure 2. Crystal structure of Cdk12•SR-4835/CycK complex.
isb_bonn retweeted
📢 We are #hiring!
🥼 We’re looking for a #postdoc to work on an exciting, collaborative project between myself & @eickelatz at the @IIIBonn and @DZNE_en in Bonn, Germany!
#job @ImmunoSens @UniklinikBonn
karriereamukb.de/offer/postd…
isb_bonn retweeted
🤩Great to host Matthias Geyer from the University of Bonn as a guest speaker in the upcoming Gene Center Seminar. Welcome Matthias!🤗
He will give a seminar on his recent groundbreaking work on the structures of inflammasome complexes.
➡️ Lynen Lecture Hall 📅December 11 🕐1 pm
isb_bonn retweeted
Very excited to have Jan Gerhartz join the group in the Nowak Lab - @UniBonn @IsbBonn. Jan is a chemist by training, with London startup experience and structural biology in Hagelueken Lab @gha14. Welcome Jan!
nowak-lab.com/
isb_bonn retweeted
1 million.
That’s how many researchers have used the #AlphaFold protein structure database since it launched in partnership with @EMBL.
It covers over 200 million predictions, giving us a comprehensive view of the protein universe. See how it was created: dpmd.ai/3RlKTQK
isb_bonn retweeted
📣PhD Jobs: We are doing another round of interviews for available #phdpositions in our lab in January.
Please RT and spread the word to #RNA enthusiasts.
Contact and apply to: kleppek (at) uni-bonn (dot) de
#phdjobs
📢 Job(s) Alert 📢
There are 3 funded PhD positions in our new lab @UniBonn @UniklinikBonn, Germany, available with a focus on #RNA, #ribosome biology and innate #immunology. Please see the ad for more info.
Please do not hesitate to get in touch with me: [email protected]
isb_bonn retweeted
Don't miss this 👇 webinar
featuring #ImmunoSensation member Matthias Geyer of @Geyer_lab @UniklinikBonn
#inflammation #webinar #science #research #NLRs #inflammasome
Free Cell Press webinar, Targeting #inflammasomes for therapies, w/ speakers Matthias Geyer @UNBonn, Rebecca Coll @QUBelfast, @WWIEM_QUB, Michael McDermott @UniversityLeeds & @cellcellpress editor Cheri Sirois Dec 15, 10:00 am ET #CPWebinars hubs.li/Q01v1jwt0
isb_bonn retweeted
Free Cell Press webinar, Targeting #inflammasomes for therapies, w/ speakers Matthias Geyer @UNBonn, Rebecca Coll @QUBelfast, @WWIEM_QUB, Michael McDermott @UniversityLeeds & @cellcellpress editor Cheri Sirois Dec 15, 10:00 am ET #CPWebinars hubs.li/Q01v1jwt0
isb_bonn retweeted
🧬⏰Time for the next Episode of #SpotOnScience:
@NielsSchneberg1 of @IsbBonn at @UniklinikBonn introduces his @Nature #publication on Antiviral sensing by #CRISPR protease.
Watch Episode #4 now youtu.be/TrCQG2Q67pU
and follow us
#immunology #science #research #inflammation
isb_bonn retweeted
🧪🎥Next up in #SpotOnScience:
@JonasMocking of @IsbBonn at @UniklinikBonn introduces his #publication on how #NLRP1 variant M1184V stabilizes the FIIND Domain.
Watch Episode #3 now youtu.be/T3ElYzpd5X8
follow us & dont miss E#4
#immunology #science #research #inflammation