@IvanovLab

Research team studying myeloid cell diversity, functions and metabolism. @LP2M_lab

 Nice, France
Joined December 2024
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  • Following80
  • Followers51
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Ivanov lab retweeted
Ivanov lab@IvanovLab6 Dec 2024
Excited to share the lab's first preprint ! We previously observed CD226+ macrophages in brown fat that resemble CCR2- and IRF4-dependent peritoneal small Macs, but we didn't know anything about them... biorxiv.org/content/10.1101/…

CD226+ adipose tissue macrophages arise from MDP-derived monocytes and regulate lipid metabolism

Macrophages are innate immune cells present in all tissues, in which they participate in immune responses and maintenance of tissue homeostasis. They develop either from embryonic precursors or from...

biorxiv.org
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Happy to see our review on macrophages of the vascular system published in Nature Cardiovascular Research ! ⁦@GwenRandolph_⁩ ⁦@jichang_han⁩ @IvanovLab nature.com/articles/s44161-0…
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🚨preprint alert! Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages (LAMs) biorxiv.org/content/10.1101/…

Identification of conserved and tissue-restricted transcriptional profiles for lipid associated...

Macrophages are essential immune cells present in all tissues, and are vital for maintaining tissue homeostasis, immune surveillance, and immune responses. Considerable efforts have identified shared...

biorxiv.org
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Ivanov lab paper ! Very happy to see our story on monocyte glucose metabolism online in ⁦@NatureComms⁩ today. Inhibition of Glut1 depletes the majority of blood monocytes, yet atherosclerotic plaques still develop normally🧐 ⁦⁦@LP2M_Lab⁩ nature.com/articles/s41467-0…

Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis...

Nature Communications - Monocytes participate in plaque formation, and adapt to metabolic changes to alter their functions. Here the authors show, using genetic mouse models and functional...

nature.com
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Happy to see this story out! @LP2M_Lab @Univ_CotedAzur @CNRS_DR20 @Bastien_Dolfi @AlexGallerand Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes - Dolfi - European Journal of Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/…

Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes

Chronic stress and sex hormones influence innate and adaptive responses. Our study found that chronic psychosocial stress increases lymphocytes in both sexes, while myelopoiesis is increased in an...

onlinelibrary.wiley.com
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Glad to share our new study investigating the unknown diversity of adrenal glands macrophages. I would like to thanks all my team and collaborators for this incredible work ! cell.com/cell-reports/fullte…

Unravelling the sex-specific diversity and functions of adrenal gland macrophages

Dolfi et al. uncover the sex-specific heterogeneity of adrenal gland macrophages and their ontogeny, maintenance, tissue distribution, and role in local lipid homeostasis.

cell.com
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Out in Nat Comms! nature.com/articles/s41467-0… Great work by @AlexGallerand, @MarionAlya, Stoyan and many others. This one is very special, and I wanted to highlight all the amazing single-cell analysis done by @mfiruleva, allowing me to do more as a senior author for the first time

Brown adipose tissue monocytes support tissue expansion

Nature Communications - Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose...

nature.com
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