Jacob Grainger retweeted
Here's the thing we're all re-learning in 2024:
To be VC-backed, you truly have to grow at insane rates
At least, Triple Triple Double Double (3x 3x 2x 2x)
Ideally, Triple Triple Triple Double Double
If that's not you, don't raise. Or stop raising. Or at least, be realistic.
Jacob Grainger retweeted
A lesson in dilution & entry prices:
Below are 2 sample startups. They're made up, but loosely based on real examples & completely feasible.
1) Company A raises a seed at a $10M valuation, raises an A for 20% dilution, then never raises again, eventually exiting for $1B.
Seed round MOIC = 80x (1B/10M * 80%)
2) Company B raises a hot seed at a $50M valuation, then 5 more rounds, totaling 80% dilution. It eventually exits for $10B, a decacorn!
Seed round MOIC = 40x (10B/50M * 20%)
In this case, a mere unicorn exit gives investors a 2x higher cash on cash return than a decacorn exit. Founders and early employees also make more $ from the former. Dilution matters. Entry price matters. Valuations alone can be misleading.
Jacob Grainger retweeted
As a long-time Seed investor @Work_Bench, I’ve seen so many founders fundraise without realizing the long-term impacts on the terms they agree to
There's no better time than YC demo day to shed some light on the various incentives & biases of different seed investors 🧵👇
Jacob Grainger retweeted
Venture Capital is F*cking hard.
With the risk free rate climbing and competition increasing it won't get any easier and a wash out is coming.
Here's some of the real math required to generate industry leading returns in this highly illiquid asset class.
Jacob Grainger retweeted
His panel, ‘Early-Stage Funds Fueling Canada’s Future’, will also feature @AllenLau of @twosmallfishvc, @IrfhanRawji of @relayventures and @JacobGGrainger of @PlugandPlayTC. If you’re at the Summit, check it out at 5 PM PST on the Main Stage!
#BKRCapital #VentureCapital
Jacob Grainger retweeted
A lot of panic re: SVB (you should see my phone/emails!). A bank run driven by panic is the real risk here, not the action of selling LT securities at loss
I have no inside information as I left SVB in 2012, but know enough about banking to piece together.
Quick 🧵
Canada’s immigration policy is a huge strength. 27% of the men on the @CanadaSoccerEN World Cup team weren’t born in Canada. As H1B visas expire due to tech industry layoffs Canada should capture that talent. Outside talent helps our country be world class. #FIFAWorldCup #layoffs
Jacob Grainger retweeted
There seem to be different measures of this: but an interesting sign that SF may be losing dominance for startup activity. cc @startupecon
yared.com/2022/09/san-franci…
The Power Law by @scmallaby is one of the best non-fiction books I’ve read in a long time. I’d highly recommend it to anyone interested in startups and VC.
Jacob Grainger retweeted
This is a powerful graphic out team created articulating the vision of Jasper Health. What is even more powerful is it comes from tons of feedback from our members. @jasperhealthinc
Jacob Grainger retweeted
1/ A year ago, there were a lot of healthcare tech companies valued on "top-line" revenue growth
That's no longer true.
So what's the right measure to value fast growing healthcare tech companies?
(thanks @BessemerVP @stephenkraus and @SofiaGuerraR)
Jacob Grainger retweeted
🚨New Second Opinion🚨
My list of 25 active pre-seed and seed investors in digital health.
* I wrote this for founders
* And for my own sanity, so I've got a cheatsheet to refer startups to awesome funds
* Plz submit your fund for the next update!
ovsecondopinion.substack.com…
Jacob Grainger retweeted
🩺 Over the next decade, healthcare tech-enabled services will be one of the most promising businesses to grow.
And we've uncovered key benchmarks on what’s “typical” and what “best in class” when building and scaling these kinds of companies.
More👇 bessemervp.team/3zvZRLI
Jacob Grainger retweeted
Three Scenarios. My latest Substack piece. I hope you enjoy it.
grahamsbenjamins.substack.co…
Jacob Grainger retweeted
Our ambition at Google Health is to improve the health of billions. My colleague Dr. Alan Karthikesalingam discusses how artificial intelligence (AI) will make a difference in healthcare buff.ly/3Qm8jUD
Jacob Grainger retweeted
Great perspective on what the broader market trends mean for digital health from @deenashakir on @YahooFinance today. “There’s a long history of regulatory constraints driving innovation.”
"Human health is recession proof," @Lux_Capital Partner @DeenaShakir says, adding: "We'll continue to get sick. We'll continue to have babies. We'll continue to have health care issues, and the pandemic really propelled a lot of the digital transformation into permanence."
Jacob Grainger retweeted
What is the future of health & biomedicine? Looking 10yrs back, and 10 forward.
My talk at #LifeItself is on @CNN, thanks to @DrSanjayGupta & @MarcHodosh
For a deeper dive read my piece here: linkedin.com/pulse/future-he…
#DigitalHealth #MedTech #MedTwitter
cnn.com/videos/health/2022/0…
Jacob Grainger retweeted
The healthcare industry is gearing up for a data interoperability overhaul. Read our latest for an overview of interoperability-focused digital health solutions + opportunities for innovators to unlock new business models and improve care delivery. rockhealth.com/insights/high…

























