Our group at @IPMB_HD explores unknown roles of RNA modifications, new methods for live cell RNA imaging, photoswitchable biomolecules and the origin of life.

Heidelberg, Alemania
Joined July 2020
📢New PhD position available in our lab in collaboration with @JaeschkeLab developing new RNA modifications. We are looking for an organic chemist with an interest in life sciences. To apply : tinyurl.com/54fmm8bj @enscmchimiemtp @umontpellier @IBMM_Balard @ChemBioNAC PLS RT
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📢Please RT📢 I'm looking for PhD and PostDoc fellows interested in #ChemicalBiology, #RNA interactomes, #Fluorophores, super-resolution #Imaging & new technologies for Spatial Biology @UniHeidelberg @IPMB_HD in my group. #ERC funded Please apply! Info: sunbulgroup.com
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I am extremely excited and honored to receive #ERCCoG to investigate complex interaction networks of disease-related RNAs @UniHeidelberg @IPMB_HD Many thanks to @ERC_Research, my family, team, colleagues and mentors for their support.
📢 Results of the 2023 ERC Consolidator Grant competition are out. €627 million for 308 researchers. Who has been offered funding? What topics and questions will they investigate? Where will they conduct their research? 🇪🇺@HorizonEU #ERCCoG news 👉 europa.eu/!qvtkcH
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Amazing discovery that will lead to a new chapter in biochemistry textbooks. #RNA-#Protein conjugates in bacteria 🙀 Congratulations to @MaikSchauerte @HoeferLab @JaeschkeLab
We are very excited to announce that our new paper has been published in @Nature! Meet the new ‘RNAylation’ reaction: a viral ADP-ribosyltransferase (ART) is able to attach #RNA chains to E. coli proteins! Congratulations @JaeschkeLab @HoeferLab UrlaubLab nature.com/articles/s41586-0…
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RNA covalently links to proteins: today in @Nature! #RNAylation as new post-translational modification (or #Proteinylation as new post-transcriptional RNA modification!) by @HoeferLab, @JaeschkeLab, @MaikSchauerte. Important during #phage infection! nature.com/articles/s41586-0…
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Excited about our publication in @Nature, unveiling an innovative process: RNAylation leading to novel #protein-#RNA conjugates. Grateful for contributions and support from @HoeferLab, @JaeschkeLab, and Urlaub Lab!
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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A decisive response to those who find t4 phage boring and believe there's nothing left to explore! Check out this great paper that will prove you wrong! Congrats to the first author @MaikSchauerte! 🙌 Proud to have contributed to such an amazing project! 🤩 @HoeferLab 💪🏽
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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Very happy to see our paper about the #RNAylation out in @Nature! This demonstrates that #phage research can still enable exciting and novel discoveries! Special thanks to @HoeferLab, as well as @JaeschkeLab and UrlaubLab for contributions and support!
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Jaeschke Lab retweeted
We hear a lot about phage-defense mechanisms, but what about phage-offense mechanisms? Really fantastic work from @HoeferLab and @MaikSchauerte after a long review process.
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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Super excited to see my Master's thesis and all the amazing work done ever since published in Nature today! 💥 Congrats to @HoeferLab @JaeschkeLab and Urlaub Lab! #RNAylation
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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RNAylation !
We are very excited to announce that our new paper has been published in @Nature! Meet the new ‘RNAylation’ reaction: a viral ADP-ribosyltransferase (ART) is able to attach #RNA chains to E. coli proteins! Congratulations @JaeschkeLab @HoeferLab UrlaubLab nature.com/articles/s41586-0…
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Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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Happy to announce that our SpyRho fluorophore for super-resolution RNA imaging is now commercially available from @spirochrome . Give it a shot if you are in RNA business😉
📢New product launch! We introduce SpyRho 555 from @Murat__Sunbul lab. SpyRho 555 is a fluorogenic dye binding to RhoBAST aptamer for live or fixed cell RNA imaging. Works for STED and PAINT-like SMLM. spirochrome.com/product/spyr… biorxiv.org/content/10.1101/… #SPYprobes #STED #imaging
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Jaeschke Lab retweeted
📢New product launch! We introduce SpyRho 555 from @Murat__Sunbul lab. SpyRho 555 is a fluorogenic dye binding to RhoBAST aptamer for live or fixed cell RNA imaging. Works for STED and PAINT-like SMLM. spirochrome.com/product/spyr… biorxiv.org/content/10.1101/… #SPYprobes #STED #imaging
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Please RT! 📢I am looking for a PhD student📢 interested in Chemical Biology, #RNA, #Fluorophores, #Imaging & developing new technologies for spatial biology @UniHeidelberg @IPMB_HD in my group. Please apply! More info: sunbulgroup.com/phd-wanted
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Excited to share our latest work! Two-photon glutamate uncaging , in-vivo two-photon imaging and behavioural experiments revealed a dendritic channelopathy underlie cognitive deficits in epilepsy which can be target pharmacologically to enhance cognition. doi.org/10.1093/brain/awac45…
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